(Q34288026)

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Device-based local delivery of siRNA against mammalian target of rapamycin (mTOR) in a murine subcutaneous implant model to inhibit fibrous encapsulation

scientific article published on August 19, 2010

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Europe PubMed Central

PubMed publication ID

1 August 2017

Device-based local delivery of siRNA against mammalian target of rapamycin (mTOR) in a murine subcutaneous implant model to inhibit fibrous encapsulation (English)

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1 August 2017

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RNA interference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20727922

20 June 2024

David W Grainger

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David W. Grainger

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20 June 2024

author name string

Hironobu Takahashi

1

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1 August 2017

Yuwei Wang

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1 August 2017

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19 August 2010

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1 August 2017

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20 June 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20727922/?tool=EBI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20727922

20 June 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20727922/pdf/?tool=EBI

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20727922

20 June 2024

https://europepmc.org/articles/PMC2975752

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20727922

20 June 2024

https://europepmc.org/articles/PMC2975752?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20727922

20 June 2024

https://doi.org/10.1016/j.jconrel.2010.08.019

online access status

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20727922

20 June 2024

https://api.elsevier.com/content/article/PII:S0168365910006747?httpAccept=text/xml

1 reference

10.1016/J.JCONREL.2010.08.019

https://api.crossref.org/works/10.1016/J.JCONREL.2010.08.019

20 June 2024

https://api.elsevier.com/content/article/PII:S0168365910006747?httpAccept=text/plain

1 reference

10.1016/J.JCONREL.2010.08.019

https://api.crossref.org/works/10.1016/J.JCONREL.2010.08.019

20 June 2024

Journal of Controlled Release

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Europe PubMed Central

PubMed publication ID

1 August 2017

147

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Europe PubMed Central

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1 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

400-407

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Polymeric nanoparticles for siRNA delivery and gene silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Hyaluronic acid-polyethyleneimine conjugate for target specific intracellular delivery of siRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Foreign body reaction to biomaterials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Interfering with disease: a progress report on siRNA-based therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

RNAi therapeutics: principles, prospects and challenges

1 reference

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6 July 2018

The phagosome: compartment with a license to kill

1 reference

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6 July 2018

Vascular endothelial growth factor and dexamethasone release from nonfouling sensor coatings affect the foreign body response

1 reference

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6 July 2018

Delivery systems for the direct application of siRNAs to induce RNA interference (RNAi) in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Modulation of collagen and MMP-1 gene expression in fibroblasts by the immunosuppressive drug rapamycin. A direct role as an antifibrotic agent?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Current status of polymeric gene delivery systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Drug/device combinations for local drug therapies and infection prophylaxis

1 reference

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6 July 2018

Inflammatory cells during wound repair: the good, the bad and the ugly

1 reference

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6 July 2018

An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons

1 reference

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6 July 2018

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

1 reference

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6 July 2018

Rapamycin: an anti-cancer immunosuppressant?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

RNA silencing and genome regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation

1 reference

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6 July 2018

Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

RNA interference targeting transforming growth factor-beta type II receptor suppresses ocular inflammation and fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Unlocking the potential of the human genome with RNA interference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

siRNA for gene silencing: a route to drug target discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Mammalian target of rapamycin positively regulates collagen type I production via a phosphatidylinositol 3-kinase-independent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Oligonucleotide‐Based Knockdown Technologies: Antisense Versus RNA Interference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Sirolimus eluting stent: a new era in interventional cardiology?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Compromised production of extracellular matrix in mice lacking secreted protein, acidic and rich in cysteine (SPARC) leads to a reduced foreign body reaction to implanted biomaterials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Novel branched poly(ethylenimine)-cholesterol water-soluble lipopolymers for gene delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Altered extracellular matrix remodeling and angiogenesis in sponge granulomas of thrombospondin 2-null mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Influence of alternatively and classically activated macrophages on fibrogenic activities of human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

6 July 2018

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

1 reference

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6 July 2018

Mechanism of action of the immunosuppressant rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975752

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Therapeutic silencing of an endogenous gene by siRNA cream in an arthritis model mouse

1 reference

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28 October 2018

Biodegradation of poly(anhydride-esters) into non-steroidal anti-inflammatory drugs and their effect on Pseudomonas aeruginosa biofilms in vitro and on the foreign-body response in vivo

1 reference

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Enhanced anti-fibrotic activity of plasmid DNA expressing small interference RNA for TGF-beta type II receptor for a mouse model of obstructive nephropathy by cationized gelatin prepared from different amine compounds

1 reference

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Local release of dexamethasone from polymer millirods effectively prevents fibrosis after radiofrequency ablation.

1 reference

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1 reference

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1 reference

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Network formation and degradation behavior of hydrogels formed by Michael-type addition reactions

1 reference

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Sustained polymeric delivery of gene silencing antisense ODNs, siRNA, DNAzymes and ribozymes: in vitro and in vivo studies.

1 reference

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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

1 reference

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Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice

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Cationic liposome-mediated delivery of siRNAs in adult mice

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Use of adeno-associated viral vector for delivery of small interfering RNA.

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The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats.

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Inhibition of mTOR reduces chronic pressure-overload cardiac hypertrophy and fibrosis

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In vitro stimulation of fibroblast activity by factors generated from human monocytes activated by biomedical polymers

1 reference

https://pubmed.ncbi.nlm.nih.gov/20727922

12 December 2020

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inferred from PubMed ID database lookup

The antifibrotic effect of TGF-beta1 siRNAs in murine model of liver cirrhosis

1 reference

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inferred from PubMed ID database lookup

Gene silencing by systemic delivery of synthetic siRNAs in adult mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20727922

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Rapamycin attenuates unilateral ureteral obstruction-induced renal fibrosis

1 reference

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1 reference

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Use of lentiviral vectors for delivery of small interfering RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/20727922

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Low-dose oral rapamycin treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20727922

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Reducing capsular thickness and enhancing angiogenesis around implant drug release systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/20727922

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JCONREL.2010.08.019

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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