(Q34293391)

English

Phase 1/2 study to assess the safety, efficacy, and pharmacokinetics of barasertib (AZD1152) in patients with advanced acute myeloid leukemia

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scholarly article

1 reference

Europe PubMed Central

1 August 2017

Phase 1/2 study to assess the safety, efficacy, and pharmacokinetics of barasertib (AZD1152) in patients with advanced acute myeloid leukemia (English)

1 reference

Europe PubMed Central

1 August 2017

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1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

object named as

Norbert Ifrah

6

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object named as

Sergio Amadori

8

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Hagop Kantarjian

17

object named as

Hagop Kantarjian

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Europe PubMed Central

1 August 2017

15

object named as

Stefan Faderl

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Europe PubMed Central

1 August 2017

Giovanni Martinelli

7

object named as

Giovanni Martinelli

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Europe PubMed Central

1 August 2017

16

object named as

Elias Jabbour

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Europe PubMed Central

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1

object named as

Bob Löwenberg

1 reference

Europe PubMed Central

1 August 2017

Pieter Sonneveld

10

object named as

Pieter Sonneveld

1 reference

Europe PubMed Central

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2

object named as

Petra Muus

1 reference

Europe PubMed Central

1 August 2017

Gert J Ossenkoppele

3

object named as

Gert Ossenkoppele

1 reference

Europe PubMed Central

1 August 2017

Paul K Stockman

13

object named as

Paul Stockman

1 reference

Europe PubMed Central

1 August 2017

Philippe Rousselot

4

object named as

Philippe Rousselot

1 reference

Europe PubMed Central

1 August 2017

author name string

Jean-Yves Cahn

5

1 reference

Europe PubMed Central

1 August 2017

Ellin Berman

9

1 reference

Europe PubMed Central

1 August 2017

Mojca Jongen-Lavrencic

11

1 reference

Europe PubMed Central

1 August 2017

Sophie Rigaudeau

12

1 reference

Europe PubMed Central

1 August 2017

Alison Goudie

14

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Europe PubMed Central

1 August 2017

language of work or name

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publication date

5 October 2011

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Europe PubMed Central

1 August 2017

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Europe PubMed Central

1 August 2017

118

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Europe PubMed Central

1 August 2017

6030-6036

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Europe PubMed Central

1 August 2017

23

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Europe PubMed Central

1 August 2017

Therapeutic advances in acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Clinical evaluation of AZD1152, an i.v. inhibitor of Aurora B kinase, in patients with solid malignant tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Independent prognostic factors for AML outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

A phase I dose-escalation study of danusertib (PHA-739358) administered as a 24-hour infusion with and without granulocyte colony-stimulating factor in a 14-day cycle in patients with advanced solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Analysis of Aurora B kinase in non-Hodgkin lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

AZD1152 rapidly and negatively affects the growth and survival of human acute myeloid leukemia cells in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Modeling the temporal evolution of the spindle assembly checkpoint and role of Aurora B kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Acute myeloid leukemia and myelodysplastic syndromes in older patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Aurora kinases: shining lights on the therapeutic horizon?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Aurora kinases link chromosome segregation and cell division to cancer susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Acute myeloid leukemia and acute promyelocytic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Two-sided confidence intervals for the single proportion: comparison of seven methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

6 July 2018

Aurora kinase inhibitor AZD1152 negatively affects the growth and survival of HTLV-1-infected T lymphocytes in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

28 October 2018

Phase I pharmacokinetic and pharmacodynamic study of the aurora kinase inhibitor danusertib in patients with advanced or metastatic solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

28 October 2018

Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4186639

28 October 2018

Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21976672

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2011-07-366930

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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0 references

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