(Q34296810)

1 August 2017

title

Development of artemisinin compounds for cancer treatment (English)

1 reference

1 August 2017

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Henry C Lai

1

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1 August 2017

Narendra P Singh

series ordinal

2

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1 August 2017

Tomikazu Sasaki

series ordinal

3

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1 August 2017

publication date

31 August 2012

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Investigational New Drugs

1 August 2017

published in

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1 August 2017

volume

31

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1 August 2017

issue

1

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1 August 2017

page(s)

230-246

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Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells

21 January 2018

1 reference

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Cytotoxicity of artemisinin-related endoperoxides to Ehrlich ascites tumor cells.

21 January 2018

1 reference

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In vitro evaluation of the cytotoxic and genotoxic effects of artemether, an antimalarial drug, in a gastric cancer cell line (PG100).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Experimental Therapy of Hepatoma with Artemisinin and Its Derivatives: In vitro and In vivo Activity, Chemosensitization, and Mechanisms of Action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin is an inhibitor of ovarian cancer cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Antiproliferative effects of artemisinin on human breast cancer cells requires the downregulated expression of the E2F1 transcription factor and loss of E2F1-target cell cycle genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artesunate induces ROS-mediated apoptosis in doxorubicin-resistant T leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin Induces Apoptosis by a Bak-Dependent Intrinsic Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artesunate reduces chicken chorioallantoic membrane neovascularisation and exhibits antiangiogenic and apoptotic activity on human microvascular dermal endothelial cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin downregulates vascular endothelial growth factor expression and induces apoptosis in chronic myeloid leukemia K562 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin accelerates c-MYC oncoprotein degradation and induces apoptosis in c-MYC-overexpressing tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Single-cell analysis of dihydroartemisinin–induced apoptosis through reactive oxygen species–mediated caspase-8 activation and mitochondrial pathway in ASTC-a-1 cells using fluorescence imaging techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

The JNK inhibitor SP600125 enhances dihydroartemisinin-induced apoptosis by accelerating Bax translocation into mitochondria in human lung adenocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Calcium and survivin are involved in the induction of apoptosis by dihydroartemisinin in human lung cancer SPC-A-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Effects of artemisinin and its derivatives on growth inhibition and apoptosis of oral cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin inactivates NF-kappaB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artesunate inhibits growth and induces apoptosis in human osteosarcoma HOS cell line in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Growth inhibitory effects of dihydroartemisinin on pancreatic cancer cells: involvement of cell cycle arrest and inactivation of nuclear factor-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Down-regulation of BMI-1 cooperates with artemisinin on growth inhibition of nasopharyngeal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artesunate enhances radiosensitivity of human non-small cell lung cancer A549 cells via increasing NO production to induce cell cycle arrest at G2/M phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Effect of oral coadministration of artesunate with ferrous sulfate on rat liver mitochondrial membrane permeability transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Yeast model uncovers dual roles of mitochondria in action of artemisinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Heme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Heme synthesis increases artemisinin-induced radical formation and cytotoxicity that can be suppressed by superoxide scavengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin is cytotoxic to papillomavirus-expressing epithelial cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin enhances radiosensitivity of human glioma cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Oxidative stress response of tumor cells: microarray-based comparison between artemisinins and anthracyclines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artemisinin inhibits inducible nitric oxide synthase and nuclear factor NF-kB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKCalpha/Raf/MAPKs and NF-kappaB/AP-1-dependent mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin inhibits angiogenesis in pancreatic cancer by targeting the NF-κB pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Inhibitory effects of artesunate on angiogenesis and on expressions of vascular endothelial growth factor and VEGF receptor KDR/flk-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1α in human rheumatoid arthritis fibroblast-like synoviocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artemisinin inhibits tumor lymphangiogenesis by suppression of vascular endothelial growth factor C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin inhibits angiogenesis induced by multiple myeloma RPMI8226 cells under hypoxic conditions via downregulation of vascular endothelial growth factor expression and suppression of vascular endothelial growth factor secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin exerts cytotoxic effects and inhibits hypoxia inducible factor-1alpha activation in C6 glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dexamethasone reduced invasiveness of human malignant glioblastoma cells through a MAPK phosphatase-1 (MKP-1) dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

SM905, an artemisinin derivative, inhibited NO and pro-inflammatory cytokine production by suppressing MAPK and NF-kappaB pathways in RAW 264.7 macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Pharmacogenomic identification of c-Myc/Max-regulated genes associated with cytotoxicity of artesunate towards human colon, ovarian and lung cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

The role of downstream signaling pathways of the epidermal growth factor receptor for Artesunate's activity in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Inhibition of human cancer cell line growth and human umbilical vein endothelial cell angiogenesis by artemisinin derivatives in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Antimalarial dihydroartemisinin also inhibits angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artesunate inhibiting angiogenesis induced by human myeloma RPMI8226 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Differential effects on angiogenesis of two antimalarial compounds, dihydroartemisinin and artemisone: implications for embryotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Antiangiogenic activity of deoxoartemisinin derivatives on chorioallantoic membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Growth inhibition activity of thioacetal artemisinin derivatives against human umbilical vein endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Synthesis and antiangiogenic activity of thioacetal artemisinin derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Synthesis and antiangiogenic activity of exo-olefinated deoxoartemisinin derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Concise synthesis and antiangiogenic activity of artemisinin-glycolipid hybrids on chorioallantoic membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

The Antimalaria Agent Artemisinin Exerts Antiangiogenic Effects in Mouse Embryonic Stem Cell-Derived Embryoid Bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Inhibitive effect of artemether on tumor growth and angiogenesis in the rat C6 orthotopic brain gliomas model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

SM934 treated lupus-prone NZB × NZW F1 mice by enhancing macrophage interleukin-10 production and suppressing pathogenic T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artesunate activates Nrf2 pathway-driven anti-inflammatory potential through ERK signaling in microglial BV2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Anti-inflammatory and immunomodulatory mechanisms of artemisinin on contact hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

The new water-soluble artemisinin derivative SM905 ameliorates collagen-induced arthritis by suppression of inflammatory and Th17 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artemisinin reduces human melanoma cell migration by down-regulating alpha V beta 3 integrin and reducing metalloproteinase 2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artemisinin inhibits in vitro and in vivo invasion and metastasis of human hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin improves the efficiency of chemotherapeutics in lung carcinomas in vivo and inhibits murine Lewis lung carcinoma cell line growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Case report of a pituitary macroadenoma treated with artemether

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Synthesis and antimalarial activity of (+)-deoxoartemisinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Antimalarial and antitumor evaluation of novel C-10 non-acetal dimers of 10beta-(2-hydroxyethyl)deoxoartemisinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

New chemical and biological aspects of artemisinin-derived trioxane dimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Synthesis of 10-substituted triazolyl artemisinins possessing anticancer activity via Huisgen 1,3-dipolar cylcoaddition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Synthesis and anticancer activity of novel amide derivatives of non-acetal deoxoartemisinin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Discovery of artemisinin-glycolipid hybrids as anti-oral cancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

If artemisinin drugs fail, what's plan B?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Developmental and reproductive toxicity studies on artemisone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Tehranolide molecule modulates the immune response, reduce regulatory T cell and inhibits tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Immunosuppressive activity of a molecule isolated from Artemisia annua on DTH responses compared with cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin can inhibit calmodulin, calmodulin-dependent phosphodiesterase activity and stimulate cellular immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin shift the immune response towards Th1, inhibit the tumor growth in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

A comparison of low-dose cyclophosphamide treatment with artemisinin treatment in reducing the number of regulatory T cells in murine breast cancer model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Tehranolide inhibits proliferation of MCF-7 human breast cancer cells by inducing G0/G1 arrest and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Synthesis of a series of novel dihydroartemisinin derivatives containing a substituted chalcone with greater cytotoxic effects in leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Anti-tumor activity of new artemisinin-chalcone hybrids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

The application of tandem aza-wittig reaction to synthesize artemisinin-guanidine hybrids and their anti-tumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Biological mechanisms of action of novel C-10 non-acetal trioxane dimers in prostate cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Second generation, orally active, antimalarial, artemisinin-derived trioxane dimers with high stability, efficacy, and anticancer activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Cytotoxicity of artesunic acid homo- and heterodimer molecules toward sensitive and multidrug-resistant CCRF-CEM leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

An artemisinin-derived dimer has highly potent anti-cytomegalovirus (CMV) and anti-cancer activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Antiprotozoal, anticancer and antimicrobial activities of dihydroartemisinin acetal dimers and monomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Anticancer and antimalarial efficacy and safety of artemisinin-derived trioxane dimers in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Stereochemistry-dependent cytotoxicity of some artemisinin derivatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Synthesis and biological evaluation of extraordinarily potent C-10 carba artemisinin dimers against P. falciparum malaria parasites and HL-60 cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Synthesis and antimalarial activity of sixteen dispiro-1,2,4, 5-tetraoxanes: alkyl-substituted 7,8,15,16-tetraoxadispiro[5.2.5. 2]hexadecanes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Deoxycholic acid-derived tetraoxane antimalarials and antiproliferatives(1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Chemical stability of the peroxide bond enables diversified synthesis of potent tetraoxane antimalarials

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

An alignment independent 3D QSAR study of the antiproliferative activity of 1,2,4,5-tetraoxanes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Different behavior of artemisinin and tetraoxane in the oxidative degradation of phospholipid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Synthesis and in vitro antimalarial activity of tetraoxane-amine/amide conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Medicinal chemistry perspectives of trioxanes and tetraoxanes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Comparison of transferrin receptors, iron content and isoferritin profile in normal and malignant human breast cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Expression of glycosylated and nonglycosylated human transferrin in mammalian cells. Characterization of the recombinant proteins with comparison to three commercially available transferrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Effects of artemisinin-tagged holotransferrin on cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Synthesis and anti-cancer activity of covalent conjugates of artemisinin and a transferrin-receptor targeting peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Targeted treatment of cancer with artemisinin and artemisinin-tagged iron-carrying compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Design, synthesis, and study of a mycobactin-artemisinin conjugate that has selective and potent activity against tuberculosis and malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Combination treatment of glioblastoma multiforme cell lines with the anti-malarial artesunate and the epidermal growth factor receptor tyrosine kinase inhibitor OSI-774.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1alpha and P-glycoprotein overexpression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Inhibition of glutathione S-transferases by antimalarial drugs possible implications for circumventing anticancer drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Molecular modes of action of artesunate in tumor cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Modulation of multidrug resistance by artemisinin, artesunate and dihydroartemisinin in K562/adr and GLC4/adr resistant cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Oral artemisinin prevents and delays the development of 7,12-dimethylbenz[a]anthracene (DMBA)-induced breast cancer in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Stability of artemisinin in aqueous environments: impact on its cytotoxic action to Ehrlich ascites tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Characterization of dihydroartemisinin-resistant colon carcinoma HCT116/R cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin-induced inhibition of proliferation in BEL-7402 cells: an analysis of the mitochondrial proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Activity of drugs from traditional Chinese medicine toward sensitive and MDR1- or MRP1-overexpressing multidrug-resistant human CCRF-CEM leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin induces apoptosis in human leukemia cells HL60 via downregulation of transferrin receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Stage-based treatment of gouty arthritis by combination therapy of traditional Chinese and Western medicines: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Transferrin overcomes drug resistance to artemisinin in human small-cell lung carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Biological activity of dihydroartemisinin in canine osteosarcoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Dihydroartemisinin inhibits growth of pancreatic cancer cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artesunate induces oncosis-like cell death in vitro and has antitumor activity against pancreatic cancer xenografts in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

The effects of artesunate on the expression of EGFR and ABCG2 in A549 human lung cancer cells and a xenograft model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Artemisinin can inhibit the calmodulin-mediated activation of phosphodiesterase in comparison with Cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

NMR Studies on Novel Antitumor Drug Candidates, Deoxoartemisinin and Carboxypropyldeoxoartemisinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Antimalarial, antimycobacterial and antiproliferative activity of phenyl substituted mixed tetraoxanes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Synthesis and Cytotoxicity Studies of Artemisinin Derivatives Containing Lipophilic Alkyl Carbon Chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9873-Z

Anti-malarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappaB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes

21 January 2018

1 reference

12 December 2020

Artemisinin induces apoptosis in human cancer cells.

1 reference

12 December 2020

Dihydroartemisinin down-regulates the expression of transferrin receptor in myeloid leukemia cells

1 reference

12 December 2020

Activity of novel plant extracts against medullary thyroid carcinoma cells

1 reference

12 December 2020

Artesunate combined with vinorelbine plus cisplatin in treatment of advanced non-small cell lung cancer: a randomized controlled trial

1 reference

12 December 2020

Artesunate inhibits angiogenesis and downregulates vascular endothelial growth factor expression in chronic myeloid leukemia K562 cells

1 reference

12 December 2020

Artemisinin-transferrin conjugate retards growth of breast tumors in the rat.

1 reference

12 December 2020

New artesunic acid homodimers: Potent reversal agents of multidrug resistance in leukemia cells

1 reference

12 December 2020

Artemisinin-derived sesquiterpene lactones as potential antitumour compounds: cytotoxic action against bone marrow and tumour cells

1 reference

12 December 2020

First study of oral Artenimol-R in advanced cervical cancer: clinical benefit, tolerability and tumor markers.

1 reference

12 December 2020

Artemisinin: an alternative treatment for oral squamous cell carcinoma

1 reference

12 December 2020

Interruption of the MEK/ERK signaling cascade promotes dihydroartemisinin-induced apoptosis in vitro and in vivo

1 reference

12 December 2020

Artesunate suppresses human endometrial carcinoma RL95-2 cell proliferation by inducing cell apoptosis

1 reference

12 December 2020

Antitumor activity of novel deoxoartemisinin monomers, dimers, and trimer

1 reference

12 December 2020

Dispiro-1,2,4,5-tetraoxanes: a new class of antimalarial peroxides

1 reference

12 December 2020

Amplification activation loop between caspase-8 and -9 dominates artemisinin-induced apoptosis of ASTC-a-1 cells

1 reference

12 December 2020

Inhibitory effects of artesunate on angiogenesis

1 reference

12 December 2020

Dihydroartemisinin inhibits the expression of vascular endothelial growth factor in K562 cells

1 reference

12 December 2020

Tehranolide could shift the immune response towards Th1 and modulate the intra-tumor infiltrated T regulatory cells

1 reference

12 December 2020

The anti-malarial artesunate is also active against cancer

1 reference

12 December 2020

Antitumor and immunomodulatory properties of artemether and its ability to reduce CD4+ CD25+ FoxP3+ T reg cells in vivo

1 reference

12 December 2020

The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells

1 reference

12 December 2020

Artesunate in the treatment of metastatic uveal melanoma--first experiences

1 reference

12 December 2020

1 reference

12 December 2020

Dihydroartiminisin inhibits the growth and metastasis of epithelial ovarian cancer

1 reference

12 December 2020

Structure determination of two oligomannoside-type glycopeptides obtained from bovine lactotransferrin, by 500 MHz 1H-NMR spectroscopy

1 reference

12 December 2020

Effects of dihydroartiminisin on proliferation and phosphorylation of mitogen-activated protein kinase in epithelial ovarian cancer cell lines

1 reference

12 December 2020

Artesunate induces prostate cancer cell line PC-3 differentiation and cell cycle arrest

1 reference

12 December 2020

Differential sensitivity of colorectal cancer cell lines to artesunate is associated with expression of beta-catenin and E-cadherin

1 reference

12 December 2020

Dihydroartemisinin induces endoplasmic reticulum stress-mediated apoptosis in HepG2 human hepatoma cells

1 reference

12 December 2020

Oral administration of dihydroartemisinin and ferrous sulfate retarded implanted fibrosarcoma growth in the rat.

1 reference

12 December 2020

Effects of artemisinin dimers on rat breast cancer cells in vitro and in vivo.

1 reference

12 December 2020

Study on anticancer effect of dihydroartemisinin on pancreatic cancer

1 reference

12 December 2020

Artesunate induces G0/G1 cell cycle arrest and iron-mediated mitochondrial apoptosis in A431 human epidermoid carcinoma cells

1 reference

12 December 2020

Dihydroartemisinin exhibits antitumor activity toward hepatocellular carcinoma in vitro and in vivo.

1 reference

12 December 2020

[Effects of dihydroartiminisin on the adhesion, migration, and invasion of epithelial ovarian cancer cells].

1 reference

12 December 2020

Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins.

1 reference

12 December 2020

Iron homeostasis: insights from genetics and animal models

1 reference

12 December 2020

Effects of artesunate on cytokinesis and G₂/M cell cycle progression of tumour cells and budding yeast.

1 reference

12 December 2020

Combination treatment of malignant B cells using the anti-CD20 antibody rituximab and the anti-malarial artesunate

1 reference

12 December 2020

Artesunate attenuates the growth of human colorectal carcinoma and inhibits hyperactive Wnt/beta-catenin pathway

1 reference

12 December 2020

Artesunate enhances TRAIL-induced apoptosis in human cervical carcinoma cells through inhibition of the NF-κB and PI3K/Akt signaling pathways.

1 reference

12 December 2020

Experimental study of the function and mechanism combining dihydroartemisinin and gemcitabine in treating pancreatic cancer

1 reference

12 December 2020

Induction of apoptosis and inhibition of cell migration and tube-like formation by dihydroartemisinin in murine lymphatic endothelial cells

1 reference

12 December 2020

The anti-malarial artemisinin inhibits pro-inflammatory cytokines via the NF-κB canonical signaling pathway in PMA-induced THP-1 monocytes

1 reference

12 December 2020

Dihydroartemisinin potentiates the cytotoxic effect of temozolomide in rat C6 glioma cells

1 reference

12 December 2020

Role of antioxidant genes for the activity of artesunate against tumor cells.

1 reference

12 December 2020

Iron, free radicals and cancer

1 reference

12 December 2020

The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis

1 reference

12 December 2020

10.1007/S10637-012-9873-Z

Identifiers

DOI

1 reference

Dimensions Publication ID

1 August 2017

1037244783

0 references

1 reference