(Q39888577)

English

Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells

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1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells (English)

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

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author name string

Andrew S Rosenthal

1

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Xiaochun Chen

2

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Jun O Liu

3

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Diana C West

4

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Paul J Hergenrother

5

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Theresa A Shapiro

6

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Gary H Posner

7

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Europe PubMed Central

PMC publication ID

15 September 2017

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publication date

1 February 2009

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Europe PubMed Central

PMC publication ID

15 September 2017

Journal of Medicinal Chemistry

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Europe PubMed Central

PMC publication ID

15 September 2017

52

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Europe PubMed Central

PMC publication ID

15 September 2017

4

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

1198-1203

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

Drug discovery for malaria: a very challenging and timely endeavor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Efficacy and safety of dihydroartemisinin-piperaquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Malaria-infected mice are cured by a single dose of novel artemisinin derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Fluoroartemisinins: metabolically more stable antimalarial artemisinin derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Inhibitors of Plasmodium falciparum methionine aminopeptidase 1b possess antimalarial activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

From artemisinin to new artemisinin antimalarials: biosynthesis, extraction, old and new derivatives, stereochemistry and medicinal chemistry requirements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Second generation, orally active, antimalarial, artemisinin-derived trioxane dimers with high stability, efficacy, and anticancer activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Artemisinin-based combinations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Targeted treatment of cancer with artemisinin and artemisinin-tagged iron-carrying compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Mechanistic perspectives for 1,2,4-trioxanes in anti-cancer therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

The global distribution of clinical episodes of Plasmodium falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Conquering the intolerable burden of malaria: what's new, what's needed: a summary.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Identification of an antimalarial synthetic trioxolane drug development candidate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Synthetic peroxides as antimalarials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

A medicinal chemistry perspective on artemisinin and related endoperoxides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Recent advances in artemisinin and its derivatives as antimalarial and antitumor agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Medical need, scientific opportunity and the drive for antimalarial drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Transferrin receptors in human tissues: their distribution and possible clinical relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

(-) methyl n-tetradeca-trans-2,4,5-trienoate, an allenic ester produced by the male dried bean beetle, Acanthoscelides obtectus (Say).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

Qinghaosu (artemisinin): an antimalarial drug from China

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

22 September 2017

C-16 artemisinin derivatives and their antimalarial and cytotoxic activities: syntheses of artemisinin monomers, dimers, trimers, and tetramers by nucleophilic additions to artemisitene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

25 September 2017

Biological mechanisms of action of novel C-10 non-acetal trioxane dimers in prostate cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

25 September 2017

A short synthesis and biological evaluation of potent and nontoxic antimalarial bridged bicyclic beta-sulfonyl-endoperoxides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

15 June 2018

A randomized trial of artesunate-mefloquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

20 August 2018

Dihydroartemisinin induces apoptosis in human leukemia cells HL60 via downregulation of transferrin receptor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

20 August 2018

Malaria-infected mice are cured by oral administration of new artemisinin derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

20 August 2018

Sulforhodamine B colorimetric assay for cytotoxicity screening.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

20 August 2018

High efficacy of two artemisinin-based combinations (artesunate + amodiaquine and artemether + lumefantrine) in Caala, Central Angola

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

20 August 2018

Artemisone--a highly active antimalarial drug of the artemisinin class

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

20 August 2018

Synthetic peroxides as antimalarials.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

20 August 2018

Liposomal doxorubicin for the treatment of hormone-refractory prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

20 August 2018

Artesunate combinations for treatment of malaria: meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

20 August 2018

Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

20 August 2018

Cytotoxic effects of 27 anticancer drugs in HeLa and MDR1-overexpressing derivative cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2698029

20 August 2018

Antimalarial sulfide, sulfone, and sulfonamide trioxanes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19186946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor activity of novel deoxoartemisinin monomers, dimers, and trimer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19186946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimalarial cyclic peroxy ketals

1 reference

https://pubmed.ncbi.nlm.nih.gov/19186946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM801484V

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 September 2017

ResearchGate publication ID

0 references

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