(Q34298024)

25071152

1 August 2017

title

p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition (English)

1 reference

1 August 2017

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Jesse Hudson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Jacqueline R Ha

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Valerie Sabourin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Ryuhjin Ahn

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Rachel La Selva

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Lauren Podmore

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Jennifer Knight

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Laura Forrest

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Nicole Beauchemin

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Michael Hallett

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Morag Park

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Josie Ursini-Siegel

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

English

0 references

publication date

28 July 2014

1 reference

25071152

Molecular and Cellular Biology

1 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

3689-3701

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

31 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4187732/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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1 reference

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p66Shc regulates vesicle-mediated secretion in mast cells by affecting F-actin dynamics.

6 July 2018

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The ShcA PTB domain functions as a biological sensor of phosphotyrosine signaling during breast cancer progression

6 July 2018

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Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer

6 July 2018

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6 July 2018

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6 July 2018

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Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity

6 July 2018

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6 July 2018

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Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response

6 July 2018

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Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer

6 July 2018

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Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

The causes of cancer revisited: "mitochondrial malignancy" and ROS-induced oncogenic transformation - why mitochondria are targets for cancer therapy

6 July 2018

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Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis

6 July 2018

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NF-kappaB and cancer: how intimate is this relationship

6 July 2018

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Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer

6 July 2018

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Supervised risk predictor of breast cancer based on intrinsic subtypes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Activation of the lifespan regulator p66Shc through reversible disulfide bond formation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Signaling through ShcA is required for transforming growth factor beta- and Neu/ErbB-2-induced breast cancer cell motility and invasion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

ShcA signalling is essential for tumour progression in mouse models of human breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

NF-kappaB and epithelial to mesenchymal transition of cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

6 July 2018

1 reference

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biological significance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

The transcriptional repressor Snail promotes mammary tumor recurrence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Basal cytokeratins and their relationship to the cellular origin and functional classification of breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

affy--analysis of Affymetrix GeneChip data at the probe level

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

p66Shc protein is upregulated by steroid hormones in hormone-sensitive cancer cells and in primary prostate carcinomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Increased Malignancy of Neu-Induced Mammary Tumors Overexpressing Active Transforming Growth Factor β1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Shc proteins are strong, independent prognostic markers for both node-negative and node-positive primary breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

A gene-expression signature as a predictor of survival in breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Molecular portraits of human breast tumours

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Elevated levels of p66 Shc are found in breast cancer cell lines and primary tumors with high metastatic potential

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

The p66shc adaptor protein controls oxidative stress response and life span in mammals

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

The ShcA SH2 domain engages a 14-3-3/PI3'K signaling complex and promotes breast cancer cell survival.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Snail and slug play distinct roles during breast carcinoma progression.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4187732

Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25071152

12 December 2020

inferred from PubMed ID database lookup

Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25071152

12 December 2020

inferred from PubMed ID database lookup

p66 Shc tumor levels show a strong prognostic correlation with disease outcome in stage IIA colon cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25071152

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/MCB.00341-14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

25071152

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25071152%20AND%20SRC:MED&resulttype=core&format=json