(Q34299026)

English

Transcriptional repressor E4-binding protein 4 (E4BP4) regulates metabolic hormone fibroblast growth factor 21 (FGF21) during circadian cycles and feeding.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20851878%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Transcriptional repressor E4-binding protein 4 (E4BP4) regulates metabolic hormone fibroblast growth factor 21 (FGF21) during circadian cycles and feeding (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20851878%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

circadian rhythm

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3

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14 February 2020

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Xin Tong

1

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14 February 2020

Marina Muchnik

2

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14 February 2020

Manish Patel

4

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14 February 2020

Nan Wu

5

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14 February 2020

Shree Joshi

6

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14 February 2020

Liangyou Rui

7

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14 February 2020

Mitchell A Lazar

8

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14 February 2020

Lei Yin

9

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14 February 2020

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17 September 2010

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14 February 2020

Journal of Biological Chemistry

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14 February 2020

285

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20851878%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

47

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20851878%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

36401-36409

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20851878%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Chronotherapy and the molecular clock: Clinical implications in oncology.

1 reference

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6 July 2018

E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha

1 reference

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6 July 2018

Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease

1 reference

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6 July 2018

Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding

1 reference

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6 July 2018

Regulation of FGF21 expression and secretion by retinoic acid receptor-related orphan receptor alpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

The mammalian circadian timing system: organization and coordination of central and peripheral clocks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

A promoter in the novel exon of hPPARgamma directs the circadian expression of PPARgamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine.

1 reference

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6 July 2018

IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

The role of clock genes in pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

The crosstalk between physiology and circadian clock proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Fibroblast growth factor 21: from pharmacology to physiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Peripheral oscillators: the driving force for food-anticipatory activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

FGFs and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Expression profile of mRNAs encoding core circadian regulatory proteins in human subcutaneous adipose tissue: correlation with age and body mass index

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

The role of fibroblast growth factor 21 (FGF21) on energy balance, glucose and lipid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Circulating fibroblast growth factor-21 is elevated in impaired glucose tolerance and type 2 diabetes and correlates with muscle and hepatic insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Harmonics of circadian gene transcription in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

FGF21: a novel prospect for the treatment of metabolic diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

The 2008 Pittendrigh/Aschoff lecture: peripheral phase coordination in the mammalian circadian timing system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

The molecular mechanism regulating the autonomous circadian expression of Topoisomerase I in NIH3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Analysis and synthesis of high-amplitude Cis-elements in the mammalian circadian clock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

The genetics of mammalian circadian order and disorder: implications for physiology and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

The meter of metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

How insulin receptor substrate proteins regulate the metabolic capacity of the liver--implications for health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Identification of negative transcriptional factor E4BP4-binding site in the mouse circadian-regulated gene Mdr2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Molecular basis for rhythmic expression of CYP3A4 in serum-shocked HepG2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Insulin-like signaling, nutrient homeostasis, and life span

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Role of ChREBP in hepatic steatosis and insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

"Feeding time" for the brain: a matter of clocks.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

PPARalpha is a key regulator of hepatic FGF21.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

ChREBP, a transcriptional regulator of glucose and lipid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

SREBP-1c and TFE3, energy transcription factors that regulate hepatic insulin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

The negative transcription factor E4BP4 is associated with circadian clock protein PERIOD2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Transcriptional regulation by insulin: from the receptor to the gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Review: The role of insulin resistance in nonalcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

FGF-21 as a novel metabolic regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

System-level identification of transcriptional circuits underlying mammalian circadian clocks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

It's all in the timing: many clocks, many outputs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Protein kinase B-alpha inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Genome-wide expression analysis of mouse liver reveals CLOCK-regulated circadian output genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Synchronization of the molecular clockwork by light- and food-related cues in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

VRILLE feeds back to control circadian transcription of Clock in the Drosophila circadian oscillator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Role of Akt/protein kinase B in metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

E4BP4/NFIL3, a PAR-related bZIP factor with many roles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Coordinated transcription of key pathways in the mouse by the circadian clock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Mop3 is an essential component of the master circadian pacemaker in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Transcriptional regulation of fatty acid synthase gene and ATP citrate-lyase gene by Sp1 and Sp3 in rat hepatocytes(1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Protein-protein interaction between the transcriptional repressor E4BP4 and the TBP-binding protein Dr1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Transcriptional repression by the human bZIP factor E4BP4: definition of a minimal repression domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

6 July 2018

Characterization of Peripheral Circadian Clocks in Adipose Tissues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172866

21 January 2018

Circadian clock-controlled intestinal expression of the multidrug-resistance gene mdr1a in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172866

21 January 2018

Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172866

21 January 2018

Circadian expression of FGF21 is induced by PPARalpha activation in the mouse liver.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172866

21 January 2018

Increased serum FGF21 levels in patients with nonalcoholic fatty liver disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172866

21 January 2018

Distinct association of serum FGF21 or adiponectin levels with clinical parameters in patients with type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172866

21 January 2018

Physiological modulation of circulating FGF21: relevance of free fatty acids and insulin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172866

21 January 2018

Clock gene expression in peripheral leucocytes of patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172866

21 January 2018

Effect of streptozotocin-induced diabetes on daily expression of per2 and dbp in the heart and liver and melatonin rhythm in the pineal gland of Wistar rat.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172866

21 January 2018

Negative control of circadian clock regulator E4BP4 by casein kinase Iepsilon-mediated phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.172866

21 January 2018

Promoter analysis of Mammalian clock controlled genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

28 October 2018

Central and peripheral circadian oscillators in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

28 October 2018

Genome-wide expression analysis in Drosophila reveals genes controlling circadian behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978569

28 October 2018

Abnormal expressions of circadian-clock and circadian clock-controlled genes in the livers and kidneys of long-term, high-fat-diet-treated mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20851878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide expression analysis reveals 100 adrenal gland-dependent circadian genes in the mouse liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/20851878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Profile of rhythmic gene expression in the livers of obese diabetic KK-A(y) mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20851878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.172866

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20851878%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20851878%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20851878%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

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