(Q36602626)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16998535%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

review article

1 reference

title

Transcriptional regulation by insulin: from the receptor to the gene (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16998535%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16998535%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Barry I Posner

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16998535%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

publication date

1 July 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16998535%20AND%20SRC:MED&resulttype=core&format=json

Canadian Journal of Physiology and Pharmacology

30 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16998535%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

84

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16998535%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

713-724

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16998535%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16998535%20AND%20SRC:MED&resulttype=core&format=json

Assessment of the roles of mitogen-activated protein kinase, phosphatidylinositol 3-kinase, protein kinase B, and protein kinase C in insulin inhibition of cAMP-induced phosphoenolpyruvate carboxykinase gene transcription

30 December 2019

cites work

1 reference

Identification of a core motif that is recognized by three members of the HMG class of transcriptional regulators: IRE-ABP, SRY, and TCF-1 alpha

21 January 2018

1 reference

Regulation of microsomal triglyceride transfer protein gene by insulin in HepG2 cells: roles of MAPKerk and MAPKp38.

21 January 2018

1 reference

Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence

21 January 2018

1 reference

Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes.

21 January 2018

1 reference

Phosphatidylinositol 3'-kinase and p70s6k are required for insulin but not bisperoxovanadium 1,10-phenanthroline (bpV(phen)) inhibition of insulin-like growth factor binding protein gene expression. Evidence for MEK-independent activation of mitogen

21 January 2018

1 reference

Transcriptional regulation of plasminogen activator inhibitor type 1 gene by insulin: insights into the signaling pathway

21 January 2018

1 reference

Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1.

21 January 2018

1 reference

FoxO proteins in insulin action and metabolism

21 January 2018

1 reference

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

21 January 2018

1 reference

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

21 January 2018

1 reference

Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells

21 January 2018

1 reference

Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways

21 January 2018

1 reference

SREBP-1c and Sp1 interact to regulate transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in the liver

21 January 2018

1 reference

Factors that control the tissue-specific transcription of the gene for phosphoenolpyruvate carboxykinase-C

21 January 2018

1 reference

Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver.

21 January 2018

1 reference

Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR.

21 January 2018

1 reference

Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

21 January 2018

1 reference

Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver

21 January 2018

1 reference

Central role for phosphatidylinositide 3-kinase in the repression of glucose-6-phosphatase gene transcription by insulin.

21 January 2018

1 reference

Insulin inhibits hepatocellular glucose production by utilizing liver-enriched transcriptional inhibitory protein to disrupt the association of CREB-binding protein and RNA polymerase II with the phosphoenolpyruvate carboxykinase gene promoter

21 January 2018

1 reference

SREBP transcription factors: master regulators of lipid homeostasis

21 January 2018

1 reference

Glycogen synthase kinase-3 regulates IGFBP-1 gene transcription through the thymine-rich insulin response element

21 January 2018

1 reference

Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt

21 January 2018

1 reference

ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose

21 January 2018

1 reference

Transcriptional regulation of fatty acid synthase gene and ATP citrate-lyase gene by Sp1 and Sp3 in rat hepatocytes(1).

21 January 2018

1 reference

Transcriptional regulation of insulin receptor gene promoter in rat hepatocytes

21 January 2018

1 reference

Insulin response sequence-dependent and -independent mechanisms mediate effects of insulin on glucocorticoid-stimulated insulin-like growth factor binding protein-1 promoter activity

21 January 2018

1 reference

A nucleoprotein complex containing CCAAT/enhancer-binding protein beta interacts with an insulin response sequence in the insulin-like growth factor-binding protein-1 gene and contributes to insulin-regulated gene expression

21 January 2018

1 reference

Functional analysis of glucocorticoid and insulin response sequences in the rat insulin-like growth factor-binding protein-1 promoter

21 January 2018

1 reference

Insulin regulation of fatty acid synthase gene transcription: roles of USF and SREBP-1c.

21 January 2018

1 reference

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

21 January 2018

1 reference

Insulin suppresses transactivation by CAAT/enhancer-binding proteins beta (C/EBPbeta). Signaling to p300/CREB-binding protein by protein kinase B disrupts interaction with the major activation domain of C/EBPbeta

21 January 2018

1 reference

The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids

21 January 2018

1 reference

Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility

21 January 2018

1 reference

Insulin-induced egr-1 and c-fos expression in 32D cells requires insulin receptor, Shc, and mitogen-activated protein kinase, but not insulin receptor substrate-1 and phosphatidylinositol 3-kinase activation

21 January 2018

1 reference

Modulation of carbohydrate response element-binding protein gene expression in 3T3-L1 adipocytes and rat adipose tissue.

21 January 2018

1 reference

Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection

21 January 2018

1 reference

Dual role for mitogen-activated protein kinase (Erk) in insulin-dependent regulation of Fra-1 (fos-related antigen-1) transcription and phosphorylation

21 January 2018

1 reference

SREBPs suppress IRS-2-mediated insulin signalling in the liver.

21 January 2018

1 reference

Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene

21 January 2018

1 reference

Mitogenic properties of insulin and insulin analogues mediated by the insulin receptor

21 January 2018

1 reference

Conserved amino acids within CCAAT enhancer-binding proteins (C/EBP(alpha) and beta) regulate phosphoenolpyruvate carboxykinase (PEPCK) gene expression

21 January 2018

1 reference

Insulin-responsive nuclear proteins facilitate Sp1 interactions with the insulin-like growth factor-I gene

21 January 2018

1 reference

Insulin-regulated expression of Egr-1 and Krox20: dependence on ERK1/2 and interaction with p38 and PI3-kinase pathways

21 January 2018

1 reference

Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways

21 January 2018

1 reference

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

21 January 2018

1 reference

Regulatory role of glycogen synthase kinase 3 for transcriptional activity of ADD1/SREBP1c

21 January 2018

1 reference

Insulin regulation of mitogen-activated protein kinase kinase (MEK), mitogen-activated protein kinase and casein kinase in the cell nucleus: a possible role in the regulation of gene expression

21 January 2018

1 reference

Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding Protein-2 at serine residues 432 and 455 in vivo.

21 January 2018

1 reference

Protein kinase B-alpha inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors

21 January 2018

1 reference

Control of the synthesis of fatty-acid synthetase in rat liver by insulin, glucagon, and adenosine 3':5' cyclic monophosphate

21 January 2018

1 reference

Insulin induction of apolipoprotein AI, role of Sp1.

21 January 2018

1 reference

Occupancy and function of the -150 sterol regulatory element and -65 E-box in nutritional regulation of the fatty acid synthase gene in living animals

21 January 2018

1 reference

Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c

21 January 2018

1 reference

Activation of protein kinase B/Akt is sufficient to repress the glucocorticoid and cAMP induction of phosphoenolpyruvate carboxykinase gene.

21 January 2018

1 reference

Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphatase and phosphoenolypyruvate carboxykinase gene expression

21 January 2018

1 reference

Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase.

21 January 2018

1 reference

O-glycosylation of Sp1 and transcriptional regulation of the calmodulin gene by insulin and glucagon

21 January 2018

1 reference

Analysis of the genes involved in the insulin transmembrane mitogenic signal in Chinese hamster ovary cells, CHO-K1, utilizing insulin-independent mutants

21 January 2018

1 reference

Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes

21 January 2018

1 reference

Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

21 January 2018

1 reference

Effects of glucose and insulin on rat apolipoprotein A-I gene expression.

21 January 2018

1 reference

Down-regulation of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by insulin: the role of the forkhead transcription factor FKHRL1

21 January 2018

1 reference

Insulin regulation of sterol regulatory element-binding protein-1 expression in L-6 muscle cells and 3T3 L1 adipocytes

21 January 2018

1 reference

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway.

21 January 2018

1 reference

DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells

21 January 2018

1 reference

Multiple liver-enriched trans-acting factors interact with the glucocorticoid- (GRU) and cAMP-(CRU) responsive units within the h-IGFBP-1 promoter

21 January 2018

1 reference

Topology of SREBP cleavage-activating protein, a polytopic membrane protein with a sterol-sensing domain.

21 January 2018

1 reference

Two 14-3-3 binding motifs are required for stable association of Forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding.

21 January 2018

1 reference

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

21 January 2018

1 reference

Identification of insulin-responsive regions in the HMG-CoA reductase promoter

21 January 2018

1 reference

Insulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activity

21 January 2018

1 reference

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

21 January 2018

1 reference

Hormonal regulation of cystathionine beta-synthase expression in liver

21 January 2018

1 reference

Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

21 January 2018

1 reference

Analysis of the role of protein kinase B (cAKT) in insulin-dependent induction of glucokinase and sterol regulatory element-binding protein 1 (SREBP1) mRNAs in hepatocytes

21 January 2018

1 reference

MAP kinases Erk1/2 phosphorylate sterol regulatory element-binding protein (SREBP)-1a at serine 117 in vitro

21 January 2018

1 reference

Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells

21 January 2018

1 reference

Role of Sp1 in insulin regulation of gene expression

21 January 2018

1 reference

Sterol regulatory element-binding protein negatively regulates microsomal triglyceride transfer protein gene transcription

21 January 2018

1 reference

Stat 5B, activated by insulin in a Jak-independent fashion, plays a role in glucokinase gene transcription

21 January 2018

1 reference

Hepatic nuclear factor 3 and nuclear factor 1 regulate 5-aminolevulinate synthase gene expression and are involved in insulin repression.

21 January 2018

1 reference

Regulation of glucose-6-phosphatase gene expression by protein kinase Balpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity

21 January 2018

1 reference

Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

21 January 2018

1 reference

Potential mechanism(s) involved in the regulation of glycogen synthesis by insulin.

21 January 2018

1 reference

A phorbol ester-insensitive AP-1 motif mediates the stimulatory effect of insulin on rat malic enzyme gene transcription.

21 January 2018

1 reference

Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity.

21 January 2018

1 reference

Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2

21 January 2018

1 reference

Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B

21 January 2018

1 reference

Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity

21 January 2018

1 reference

Mammalian Krüppel-like transcription factors: more than just a pretty finger

21 January 2018

1 reference

The three insulin response sequences in the glucose-6-phosphatase catalytic subunit gene promoter are functionally distinct

21 January 2018

1 reference

Insulin-response element-binding protein 1: a novel Akt substrate involved in transcriptional action of insulin

21 January 2018

1 reference

A Forkhead/winged helix-related transcription factor mediates insulin-increased plasminogen activator inhibitor-1 gene transcription.

21 January 2018

1 reference

Insulin regulation of glucose-6-phosphate dehydrogenase gene expression is rapamycin-sensitive and requires phosphatidylinositol 3-kinase.

21 January 2018

1 reference

Upstream stimulatory factors bind to insulin response sequence of the fatty acid synthase promoter. USF1 is regulated

21 January 2018

1 reference

Insulin stimulation of the fatty acid synthase promoter is mediated by the phosphatidylinositol 3-kinase pathway. Involvement of protein kinase B/Akt

21 January 2018

1 reference

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

21 January 2018

1 reference

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

21 January 2018

1 reference

Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis

21 January 2018

1 reference

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

21 January 2018

1 reference

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

21 January 2018

1 reference

Gene- and activation-specific mechanisms for insulin inhibition of basal and glucocorticoid-induced insulin-like growth factor binding protein-1 and phosphoenolpyruvate carboxykinase transcription. Roles of forkhead and insulin response sequences

21 January 2018

1 reference

The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulin

21 January 2018

1 reference

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

21 January 2018

1 reference

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

21 January 2018

1 reference

Insulin inhibits transcription of IRS-2 gene in rat liver through an insulin response element (IRE) that resembles IREs of other insulin-repressed genes

21 January 2018

1 reference

Activation of apolipoprotein AI gene expression by protein kinase A and kinase C through transcription factor, Sp1.

21 January 2018

1 reference

Epidermal growth factor induction of apolipoprotein A-I is mediated by the Ras-MAP kinase cascade and Sp1.

21 January 2018

1 reference

The role of PI 3-kinase in insulin action

21 January 2018

1 reference

Phosphatidylinositol 3-Kinase, but Not p70/p85 Ribosomal S6 Protein Kinase, Is Required for the Regulation of Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression by Insulin

21 January 2018

1 reference

Activation of the Ras Mitogen-activated Protein Kinase-Ribosomal Protein Kinase Pathway Is Not Required for the Repression of Phosphoenolpyruvate Carboxykinase Gene Transcription by Insulin

21 January 2018

1 reference

Inhibition of transcription of the phosphoenolpyruvate carboxykinase gene by insulin

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1139/Y05-152

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16998535%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference