(Q34306714)

1 August 2017

title

Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin (English)

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1 August 2017

main subject

Plasmodium falciparum

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11 September 2018

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ChEBI release 2020-05-28

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Stephan Meister

9

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Elizabeth Winzeler

object named as

Elizabeth A Winzeler

25

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author name string

Dominic Hoepfner

1

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1 August 2017

Case W McNamara

2

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1 August 2017

Chek Shik Lim

3

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1 August 2017

Christian Studer

4

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1 August 2017

Ralph Riedl

5

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1 August 2017

Thomas Aust

6

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1 August 2017

Susan L McCormack

7

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1 August 2017

David M Plouffe

8

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1 August 2017

Sven Schuierer

10

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1 August 2017

Uwe Plikat

11

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1 August 2017

Nicole Hartmann

12

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1 August 2017

Frank Staedtler

13

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1 August 2017

Simona Cotesta

14

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1 August 2017

Esther K Schmitt

15

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1 August 2017

Frank Petersen

16

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1 August 2017

Frantisek Supek

17

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1 August 2017

Richard J Glynne

18

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1 August 2017

John A Tallarico

19

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1 August 2017

Jeffrey A Porter

20

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1 August 2017

Mark C Fishman

21

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1 August 2017

Christophe Bodenreider

22

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1 August 2017

Thierry T Diagana

23

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1 August 2017

N Rao Movva

24

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1 August 2017

publication date

1 June 2012

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1 August 2017

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1 August 2017

volume

11

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1 August 2017

issue

6

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1 August 2017

page(s)

654-663

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Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

1 August 2017

cites work

1 reference

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6 July 2018

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6 July 2018

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6 July 2018

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Selective inhibitors of methionyl-tRNA synthetase have potent activity against Trypanosoma brucei Infection in Mice

6 July 2018

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Validation of isoleucine utilization targets in Plasmodium falciparum

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum

6 July 2018

1 reference

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Two crystal structures of lysyl-tRNA synthetase from Bacillus stearothermophilus in complex with lysyladenylate-like compounds: insights into the irreversible formation of the enzyme-bound adenylate of L-lysine hydroxamate

6 July 2018

1 reference

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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

6 July 2018

1 reference

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Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility

6 July 2018

1 reference

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Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation

6 July 2018

1 reference

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An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site

6 July 2018

1 reference

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In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin

6 July 2018

1 reference

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Biochemical and genetic analysis of the yeast proteome with a movable ORF collection

6 July 2018

1 reference

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Prospects for aminoacyl-tRNA synthetase inhibitors as new antimicrobial agents

6 July 2018

1 reference

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Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response

6 July 2018

1 reference

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Functional profiling of the Saccharomyces cerevisiae genome

6 July 2018

1 reference

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Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.

6 July 2018

1 reference

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Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391680

Genomic profiling of drug sensitivities via induced haploinsufficiency.

6 July 2018

1 reference

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Interaction of pseudomonic acid A with Escherichia coli B isoleucyl-tRNA synthetase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391680

Cladosporin, a new antifungal metabolite from Cladosporium cladosporioides.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391680

The yeast lysyl-tRNA synthetase gene. Evidence for general amino acid control of its expression and domain structure of the encoded protein

6 July 2018

1 reference

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Inflammation-associated gene transcription and expression in mouse lungs induced by low molecular weight compounds from fungi from the built environment

6 July 2018

1 reference

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Genome-wide analysis of barcoded Saccharomyces cerevisiae gene-deletion mutants in pooled cultures.

28 October 2018

1 reference

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The effects of anti-bacterials on the malaria parasite Plasmodium falciparum.

28 October 2018

1 reference

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Metabolic products of microorganisms. 184. On the mode of action of cladosporin

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22704625

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CHOM.2012.04.015

1 reference

1 August 2017

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1 August 2017

1 reference