(Q34315365)

1 August 2017

Inhibition of cancer cell proliferation by PPARγ is mediated by a metabolic switch that increases reactive oxygen species levels (English)

1 reference

1 August 2017

reactive oxygen species

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Zeping Hu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Ralf Kittler

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

11

Ralph J DeBerardinis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

4

Jessica Sudderth

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Nishi Srivastava

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Rahul K Kollipara

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Hien Nguyen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Shan Wang

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Caroline G Humphries

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Ryan Carstens

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Kenneth E Huffman

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

publication date

25 September 2014

1 reference

1 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

650-661

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

4 June 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4191999

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Glutamine and cancer: cell biology, physiology, and clinical opportunities

1 reference

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Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice

6 July 2018

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A comprehensive nuclear receptor network for breast cancer cells

6 July 2018

1 reference

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PPARγ isoforms differentially regulate metabolic networks to mediate mouse prostatic epithelial differentiation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Research resource: Diagnostic and therapeutic potential of nuclear receptor expression in lung cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells

6 July 2018

1 reference

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Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Otto Warburg's contributions to current concepts of cancer metabolism

6 July 2018

1 reference

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Hallmarks of Cancer: The Next Generation

6 July 2018

1 reference

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Regulation of cancer cell metabolism

6 July 2018

1 reference

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Enrichment map: a network-based method for gene-set enrichment visualization and interpretation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Identification of small molecule inhibitors of pyruvate kinase M2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Genomic antagonism between retinoic acid and estrogen signaling in breast cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

The Randle cycle revisited: a new head for an old hat.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Understanding the Warburg effect: the metabolic requirements of cell proliferation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

PPARgamma and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

6 July 2018

1 reference

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Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin.

6 July 2018

1 reference

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Cancer cell metabolism: Warburg and beyond

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

MEME: discovering and analyzing DNA and protein sequence motifs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Active Localization of the Retinoblastoma Protein in Chromatin and Its Response to S Phase DNA Damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

On the Origin of Cancer Cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Toucan: deciphering the cis-regulatory logic of coregulated genes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Peroxisome proliferator-activated receptor gamma and cancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Peroxisome proliferator-activated receptor gamma and metabolic disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Low-temperature carbon utilization is regulated by novel gene activity in the heart of a hibernating mammal

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191999

The nuclear receptor PPARgamma - bigger than fat

6 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25264247

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Targeted upregulation of pyruvate dehydrogenase kinase (PDK)-4 in slow-twitch skeletal muscle underlies the stable modification of the regulatory characteristics of PDK induced by high-fat feeding

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25264247

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2014.08.003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25264247%20AND%20SRC:MED&resulttype=core&format=json