(Q34328532)

1 August 2017

title

Bcl-xL overexpression blocks bax-mediated mitochondrial contact site formation and apoptosis in rod photoreceptors of lead-exposed mice (English)

1 reference

1 August 2017

main subject

photoreceptor protein

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1 reference

1 reference

1 reference

Lihua He

1

1 reference

1 August 2017

Guy A Perkins

2

1 reference

1 August 2017

Ann T Poblenz

3

1 reference

1 August 2017

Jeffrey B Harris

4

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1 August 2017

Michael Hung

5

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1 August 2017

Mark H Ellisman

6

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1 August 2017

Donald A Fox

7

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1 August 2017

language of work or name

English

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publication date

22 January 2003

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

100

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1 August 2017

issue

3

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1 August 2017

page(s)

1022-1027

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Bax releases cytochrome c preferentially from a complex between porin and adenine nucleotide translocator. Hexokinase activity suppresses this effect

1 August 2017

cites work

1 reference

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Contact sites between the outer and inner membrane of mitochondria-role in protein transport

6 July 2018

1 reference

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Biphasic translocation of Bax to mitochondria

6 July 2018

1 reference

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Topology of the mitochondrial inner membrane: dynamics and bioenergetic implications.

6 July 2018

1 reference

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A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis

6 July 2018

1 reference

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Transgenic Bcl-2 expressed in photoreceptor cells confers both death-sparing and death-inducing effects

6 July 2018

1 reference

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The pro-apoptotic Bcl-2 family member tBid localizes to mitochondrial contact sites

6 July 2018

1 reference

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

A mitochondrial perspective on cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Synergistic effect of Bcl-2 and BAG-1 on the prevention of photoreceptor cell death.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Cytochrome c release from isolated rat liver mitochondria can occur independently of outer-membrane rupture: possible role of contact sites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Biochemical pathways of caspase activation during apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Recent structural insight into mitochondria gained by microscopy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Mitochondrial transport of cations: channels, exchangers, and permeability transition.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Retinitis pigmentosa: defined from a molecular point of view

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Cytochrome c release from brain mitochondria is independent of the mitochondrial permeability transition.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Apoptotic cell death in retinal degenerations.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Immortalization of osteoclast precursors by targeting Bcl -XL and Simian virus 40 large T antigen to the osteoclast lineage in transgenic mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Dual-axis tomography: an approach with alignment methods that preserve resolution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Electron tomography of large, multicomponent biological structures

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Electron tomography of neuronal mitochondria: three-dimensional structure and organization of cristae and membrane contacts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Dopamine inhibits mammalian photoreceptor Na+,K+-ATPase activity via a selective effect on the alpha3 isozyme

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Cancer-associated retinopathy.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Opsin, G-protein and 48-kDa protein in normal and rd mouse retinas: developmental expression of mRNAs and proteins and light/dark cycling of mRNAs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Lead and calcium produce rod photoreceptor cell apoptosis by opening the mitochondrial permeability transition pore.

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

A one-hit model of cell death in inherited neuronal degenerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

Substrate-dependent effects of calcium on rat retinal mitochondrial respiration: physiological and toxicological studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

Rate-limiting step preceding cytochrome c release in cells primed for Fas-mediated apoptosis revealed by analysis of cellular mosaicism of respiratory changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

Modulation of mitochondrial Ca(2+) homeostasis by Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

Cytochrome c release occurs via Ca2+-dependent and Ca2+-independent mechanisms that are regulated by Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

Bax is not the heterodimerization partner necessary for sustained anti-photoreceptor-cell-death activity of Bcl-2.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

The retina of c-fos-/- mice: electrophysiologic, morphologic and biochemical aspects.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Functional alterations and apoptotic cell death in the retina following developmental or adult lead exposure.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=298719

Rods are selectively altered by lead: II. Ultrastructure and quantitative histology

27 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

A pathologic study of photoreceptor cell death in retinal photic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

Calcium overload triggers rod photoreceptor apoptotic cell death in chemical-induced and inherited retinal degenerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

Oxygen consumption in the rat outer and inner retina: light- and pharmacologically-induced inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

Influence of Ca2+ on the isolation from rat brain mitochondria of a fraction enriched of boundary membrane contact sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0333594100

Possible role of non-bilayer lipids in the structure of mitochondria. A freeze-fracture electron microscopy study

21 January 2018

1 reference

12 December 2020

Increased ERG a- and b-wave amplitudes in 7- to 10-year-old children resulting from prenatal lead exposure

1 reference

12 December 2020

Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation

1 reference

12 December 2020

The effect of calcium on mitochondrial contact sites: a study on isolated rat hearts

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0333594100

1 reference

1 August 2017

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1 August 2017

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