(Q34330916)

1 August 2017

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title

Targeting telomeres and telomerase. (English)

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1 August 2017

Sun D

1

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1 August 2017

Hurley LH

series ordinal

2

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1 August 2017

language of work or name

English

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publication date

1 January 2001

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1 August 2017

published in

Methods in Enzymology

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1 August 2017

volume

340

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1 August 2017

page(s)

573-592

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Structure and function of telomeres

1 August 2017

cites work

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7 January 2021

Telomeres and their synthesis

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7 January 2021

Structure and function of telomeres

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7 January 2021

Telomeres shorten during ageing of human fibroblasts

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7 January 2021

Telomeres and telomerase in aging and cancer

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7 January 2021

TRF2 Protects Human Telomeres from End-to-End Fusions

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7 January 2021

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7 January 2021

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

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7 January 2021

Telomere reduction in human colorectal carcinoma and with ageing

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7 January 2021

In vivo loss of telomeric repeats with age in humans

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7 January 2021

Telomere end-replication problem and cell aging

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7 January 2021

The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

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7 January 2021

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

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7 January 2021

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

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7 January 2021

Telomere terminal transferase activity from Euplotes crassus adds large numbers of TTTTGGGG repeats onto telomeric primers

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7 January 2021

The RNA component of human telomerase

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7 January 2021

Functional characterization and developmental regulation of mouse telomerase RNA.

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7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

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7 January 2021

Reverse transcriptase motifs in the catalytic subunit of telomerase

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7 January 2021

Human telomerase contains evolutionarily conserved catalytic and structural subunits

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7 January 2021

TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family

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7 January 2021

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Role of telomerase in cellular proliferation and cancer

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7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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7 January 2021

Essential role of mouse telomerase in highly proliferative organs

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7 January 2021

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

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7 January 2021

A survey of telomerase activity in human cancer

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7 January 2021

The biology of replicative senescence

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https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

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7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

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7 January 2021

Myc activates telomerase

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7 January 2021

Telomerase activity does not always imply telomere maintenance

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7 January 2021

Creation of human tumour cells with defined genetic elements

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7 January 2021

Inhibition of telomerase limits the growth of human cancer cells.

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https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow

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https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Changes in telomerase activity and telomere length during human T lymphocyte senescence

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7 January 2021

Telomere elongation in immortal human cells without detectable telomerase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

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https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Agents that target telomerase and telomeres

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7 January 2021

The effects of nucleoside analogs on telomerase and telomeres in Tetrahymena

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7 January 2021

Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines

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7 January 2021

Treatment of prostate cancer in vitro and in vivo with 2-5A-anti-telomerase RNA component.

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7 January 2021

2-5A antisense directed against telomerase RNA produces apoptosis in ovarian cancer cells

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7 January 2021

Detection of telomerase activity in Chinese hamster V79 cells and its inhibition by 7-deaza-deoxy guanosine triphosphate and (TTAGGG)4 in vitro

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7 January 2021

Inhibition of telomerase activity of melanoma cells in vitro by antisense oligonucleotides.

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7 January 2021

Cellular delivery of peptide nucleic acids and inhibition of human telomerase

1 reference

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7 January 2021

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

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https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

BCL-2 antisense therapy in patients with non-Hodgkin lymphoma

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7 January 2021

Altering specific telomerase RNA template residues affects active site function

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7 January 2021

Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase

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7 January 2021

Template boundary in a yeast telomerase specified by RNA structure

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7 January 2021

A nucleic acid triple helix formed by a peptide nucleic acid-DNA complex

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7 January 2021

Identification of determinants for inhibitor binding within the RNA active site of human telomerase using PNA scanning

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https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Hsp90 chaperones protein folding in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Hsp90 & Co. - a holding for folding

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Functional requirement of p23 and Hsp90 in telomerase complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Modular folding and evidence for phosphorylation-induced stabilization of an hsp90-dependent kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Telomerase activity in human breast tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP).

1 reference

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7 January 2021

Non-radioisotopic and semi-quantitative procedure for terminal repeat amplification protocol.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Telomerase assay using biotinylated-primer extension and magnetic separation of the products

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Inhibition of human telomerase by a G-quadruplex-interactive compound

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Regulation of catalytic activity and processivity of human telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Mammalian telomeres end in a large duplex loop

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Discovering new ADP-ribose polymer cycles: protecting the genome and more

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Sequence-specific DNA recognition by the myb-like domain of the human telomere binding protein TRF1: a model for the protein-DNA complex

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

G-quadruplex DNA: a potential target for anti-cancer drug design

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Preclinical and clinical strategies for development of telomerase and telomere inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

G-quadruplexes as targets for drug design

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Anthracene-9,10-diones as potential anticancer agents. Synthesis, DNA-binding, and biological studies on a series of 2,6-disubstituted derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Molecular Anchoring of Duplex and Triplex DNA by Disubstituted Anthracene-9,10-diones: Calorimetric, UV Melting, and Competition Dialysis Studies

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Substituent position dictates the intercalative DNA-binding mode for anthracene-9,10-dione antitumor drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

2,7-Disubstituted amidofluorenone derivatives as inhibitors of human telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Photodynamic therapy: a promising new modality for the treatment of cancer.

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7 January 2021

Porphyrin binding to quadrupled T4G4.

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7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

NMR-Based model of a telomerase-inhibiting compound bound to G-quadruplex DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Accelerated assembly of G-quadruplex structures by a small molecule

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

DNA molecules can drive the assembly of other DNA molecules into specific four-stranded structures

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Characterization of a G-quartet formation reaction promoted by the beta-subunit of the Oxytricha telomere-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Inhibition of unwinding of G-quadruplex structures by Sgs1 helicase in the presence of N,N'-bis[2-(1-piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic diimide, a G-quadruplex-interactive ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Poly(ADP-ribose) polymerase: a molecular nick-sensor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

A DNA polymerase stop assay for G-quadruplex-interactive compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

Sequence and structural selectivity of nucleic acid binding ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2801%2940443-5

7 January 2021

10.1016/S0076-6879(01)40443-5

Identifiers

DOI

1 reference

release_oogpydswxrglrj6ajlm76njtpm

1 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/oogpydswxrglrj6ajlm76njtpm

24 November 2022

mapped directly with Wikidata item

1 reference