(Q34335802)

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Apoptosis of osteosarcoma cultures by the combination of the cyclin-dependent kinase inhibitor SCH727965 and a heat shock protein 90 inhibitor.

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27 February 2020

Apoptosis of osteosarcoma cultures by the combination of the cyclin-dependent kinase inhibitor SCH727965 and a heat shock protein 90 inhibitor (English)

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27 February 2020

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27 February 2020

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27 February 2020

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S S Sharma

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27 February 2020

L Ma

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27 February 2020

B Chu

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27 February 2020

M M Bui

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27 February 2020

W J Pledger

7

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27 February 2020

publication date

28 March 2013

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27 February 2020

Cell Death and Disease

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27 February 2020

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27 February 2020

e566

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27 February 2020

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Creative Commons Attribution 3.0 Unported

1 March 2013

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April 2022 Public Data File from Crossref

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0 references

A meta-analysis of osteosarcoma outcomes in the modern medical era

1 reference

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Targeting HSP 90 induces apoptosis and inhibits critical survival and proliferation pathways in multiple myeloma

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6 July 2018

The cyclin-dependent kinase inhibitor SCH 727965 (dinacliclib) induces the apoptosis of osteosarcoma cells

1 reference

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6 July 2018

Pyrazolo[4,3-d]pyrimidine bioisostere of roscovitine: evaluation of a novel selective inhibitor of cyclin-dependent kinases with antiproliferative activity

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High-content, high-throughput analysis of cell cycle perturbations induced by the HSP90 inhibitor XL888

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6 July 2018

Dinaciclib (SCH 727965), a novel and potent cyclin-dependent kinase inhibitor.

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6 July 2018

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

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6 July 2018

Hsp90: a drug target?

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Discovery and development of Hsp90 inhibitors: a promising pathway for cancer therapy

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6 July 2018

Targeting HSP70: the second potentially druggable heat shock protein and molecular chaperone?

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6 July 2018

Involvement of p21Waf1/Cip1 cleavage during roscovitine-induced apoptosis in non-small cell lung cancer cells.

1 reference

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6 July 2018

Impact of roscovitine, a selective CDK inhibitor, on cancer cells: bi-functionality increases its therapeutic potential

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MDM2 acts downstream of p53 as an E3 ligase to promote FOXO ubiquitination and degradation.

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Principles of cancer therapy: oncogene and non-oncogene addiction

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6 July 2018

Osteosarcoma: Conventional treatment vs. gene therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3613821

6 July 2018

A stress protein interface of innate immunity

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6 July 2018

Inhibition of Hsp90 leads to cell cycle arrest and apoptosis in human malignant pleural mesothelioma

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6 July 2018

Current status and perspectives regarding the treatment of osteo-sarcoma: chemotherapy

1 reference

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6 July 2018

Dual targeting of HSC70 and HSP72 inhibits HSP90 function and induces tumor-specific apoptosis

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6 July 2018

4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer

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6 July 2018

HSP90 antagonist, geldanamycin, inhibits proliferation, induces apoptosis and blocks migration of rhabdomyosarcoma cells in vitro and seeding into bone marrow in vivo

1 reference

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Inhibition of Hsp90 function by ansamycins causes downregulation of cdc2 and cdc25c and G(2)/M arrest in glioblastoma cell lines.

1 reference

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The Bcl-2 apoptotic switch in cancer development and therapy

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Necrotic death as a cell fate

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HSP90 and the chaperoning of cancer

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Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6.

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Genes and Proteins Governing the Cellular Sensitivity to HSP90 Inhibitors: A Mechanistic Perspective

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1 reference

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1 reference

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21 January 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23538447

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the oncogene product p185erbB-2 in vitro and in vivo by geldanamycin and dihydrogeldanamycin derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/23538447

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based on heuristic

inferred from PubMed ID database lookup

Alpha1,3 fucosyltransferase VII plays a role in colorectal carcinoma metastases by promoting the carbohydration of glycoprotein CD24.

1 reference

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7 January 2021

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10.1038/CDDIS.2013.101

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23538447%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

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Europe PubMed Central

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27 February 2020

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27 February 2020

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