(Q34336500)

1 August 2017

title

3-Hydroxypyridin-2-thione as novel zinc binding group for selective histone deacetylase inhibition (English)

1 reference

1 August 2017

4

Milan Mrksich

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author name string

Vishal Patil

1

1 reference

1 August 2017

Quaovi H Sodji

2

1 reference

1 August 2017

James R Kornacki

3

1 reference

1 August 2017

Adegboyega K Oyelere

5

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1 August 2017

language of work or name

English

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publication date

18 April 2013

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Journal of Medicinal Chemistry

1 August 2017

published in

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1 August 2017

volume

56

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1 August 2017

issue

9

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1 August 2017

page(s)

3492-3506

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Targeted cancer therapy: giving histone deacetylase inhibitors all they need to succeed

1 August 2017

cites work

1 reference

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Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors

6 July 2018

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Molecular basis for the actions of Hsp90 inhibitors and cancer therapy

6 July 2018

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Selective inhibition of histone deacetylase 6 (HDAC6) induces DNA damage and sensitizes transformed cells to anticancer agents

6 July 2018

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HDAC Inhibition Attenuates Inflammatory, Hypertrophic, and Hypertensive Responses in Spontaneously Hypertensive Rats

6 July 2018

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Non-peptide macrocyclic histone deacetylase inhibitors derived from tricyclic ketolide skeleton

6 July 2018

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Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin A

6 July 2018

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Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group

6 July 2018

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Multiple roles of HDAC inhibition in neurodegenerative conditions.

6 July 2018

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Non-cancer uses of histone deacetylase inhibitors: effects on infectious diseases and beta-hemoglobinopathies

6 July 2018

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HDAC expression and clinical prognosis in human malignancies

6 July 2018

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6 July 2018

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In vitro solubility assays in drug discovery

6 July 2018

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The activity of HDAC8 depends on local and distal sequences of its peptide substrates

6 July 2018

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A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas

6 July 2018

1 reference

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Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

6 July 2018

1 reference

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Cancer epigenomics: DNA methylomes and histone-modification maps

6 July 2018

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The design of inhibitors for medicinally relevant metalloproteins

6 July 2018

1 reference

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Antitumor effects of a novel phenylbutyrate-based histone deacetylase inhibitor, (S)-HDAC-42, in prostate cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Non-hydroxamate histone deacetylase inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Acetylation and deacetylation of non-histone proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Histone deacetylase inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

The design, structure, and clinical update of small molecular weight matrix metalloproteinase inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Prediction of intestinal permeability

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Design and therapeutic application of matrix metalloproteinase inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Histone acetylation in chromatin structure and transcription

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

High-throughput screening of small molecule libraries using SAMDI mass spectrometry

6 July 2018

1 reference

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Synthesis, structure and spectroscopy of new thiopyrone and hydroxypyridinethione transition-metal complexes

27 October 2018

1 reference

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Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

New beginnings for matrix metalloproteinase inhibitors: identification of high-affinity zinc-binding groups

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Pyran-containing sulfonamide hydroxamic acids: potent MMP inhibitors that spare MMP-1.

27 October 2018

1 reference

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Carbamoylphosphonate-based matrix metalloproteinase inhibitor metal complexes: solution studies and stability constants. Towards a zinc-selective binding group

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Histone Deacetylase Inhibitors

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Trifluoromethyl ketones as inhibitors of histone deacetylase

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3657749

Metal complexes of salicylhydroxamic acid (H2Sha), anthranilic hydroxamic acid and benzohydroxamic acid. Crystal and molecular structure of [Cu(phen)2(Cl)]Cl x H2Sha, a model for a peroxidase-inhibitor complex

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23547652

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM301769U

1 reference

1 August 2017

1 reference

1 August 2017

1 reference