(Q34747237)

4 August 2017

title

A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas (English)

1 reference

4 August 2017

1 reference

S Balasubramanian

1

1 reference

4 August 2017

J Ramos

2

1 reference

4 August 2017

W Luo

3

1 reference

4 August 2017

M Sirisawad

4

1 reference

4 August 2017

E Verner

5

1 reference

4 August 2017

J J Buggy

6

1 reference

4 August 2017

publication date

7 February 2008

1 reference

4 August 2017

1 reference

4 August 2017

volume

22

1 reference

4 August 2017

issue

5

1 reference

4 August 2017

page(s)

1026-1034

1 reference

https://scigraph.springernature.com/pub.10.1038/leu.2008.9

4 August 2017

exact match

0 references

cites work

Histone deacetylases (HDACs): characterization of the classical HDAC family

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Acetylation and deacetylation of non-histone proteins

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Class II histone deacetylases: versatile regulators

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Drug insight: Histone deacetylase inhibitors--development of the new targeted anticancer agent suberoylanilide hydroxamic acid

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Histone deacetylase inhibitors: molecular mechanisms of action

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

HDAC inhibitors overcome first hurdle

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Anticancer activities of histone deacetylase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Histone deacetylase inhibitors in clinical development

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Identification of novel isoform-selective inhibitors within class I histone deacetylases

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Will broad-spectrum histone deacetylase inhibitors be superseded by more specific compounds?

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Toward selective histone deacetylase inhibitor design: homology modeling, docking studies, and molecular dynamics simulations of human class I histone deacetylases

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Cloning and characterization of a novel human histone deacetylase, HDAC8

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Histone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Negative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase A

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Kinetics and comparative reactivity of human class I and class IIb histone deacetylases

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Early features of apoptosis detected by four different flow cytometry assays

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Apoptosis induced by histone deacetylase inhibitors in leukemic cells is mediated by Bim and Noxa.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell line

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Phospholipase C-gamma: diverse roles in receptor-mediated calcium signaling

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Phospholipase cgamma1 is required for activation of store-operated channels in human keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Modulation of intracellular calcium concentrations and T cell activation by prickly pear polyphenols

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Depletion of intracellular Ca2+ store itself may be a major factor in thapsigargin-induced ER stress and apoptosis in PC12 cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Basiliolides, a class of tetracyclic C19 dilactones from Thapsia garganica, release Ca(2+) from the endoplasmic reticulum and regulate the activity of the transcription factors nuclear factor of activated T cells, nuclear factor-kappaB, and activato

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Requirement of biphasic calcium release from the endoplasmic reticulum for Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Participation of endoplasmic reticulum and mitochondrial calcium handling in apoptosis: more than just neighborhood?

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Regulation of phospholipase C gamma isoforms in haematopoietic cells: why one, not the other?

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Phospholipase Cgamma2 is essential in the functions of B cell and several Fc receptors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Selective Itk inhibitors block T-cell activation and murine lung inflammation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Recruitment and activation of PLCgamma1 in T cells: a new insight into old domains

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Families of phosphoinositide-specific phospholipase C: structure and function

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

A spectrophotometric assay for histone deacetylase 8.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.9

7 January 2021

Identifiers

DOI

10.1038/LEU.2008.9

1 reference

Dimensions Publication ID

4 August 2017

1032266708

0 references

1 reference