(Q34340593)

1 August 2017

Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia (English)

1 reference

acute promyelocytic leukemia

1 August 2017

1 reference

1 reference

16

Michelle M Le Beau

1 reference

1 August 2017

Letetia Jones

1

1 reference

1 August 2017

Guangwei Wei

2

1 reference

1 August 2017

Sabina Sevcikova

3

1 reference

1 August 2017

Vernon Phan

4

1 reference

1 August 2017

Sachi Jain

5

1 reference

1 August 2017

Angell Shieh

6

1 reference

1 August 2017

Jasmine C Y Wong

7

1 reference

1 August 2017

Min Li

8

1 reference

1 August 2017

Joshua Dubansky

9

1 reference

1 August 2017

Mei Lin Maunakea

10

1 reference

1 August 2017

Rachel Ochoa

11

1 reference

1 August 2017

George Zhu

12

1 reference

1 August 2017

Thelma R Tennant

13

1 reference

1 August 2017

Kevin M Shannon

14

1 reference

1 August 2017

Scott W Lowe

15

1 reference

1 August 2017

Scott C Kogan

17

1 reference

1 August 2017

language of work or name

English

0 references

publication date

8 November 2010

1 reference

Journal of Experimental Medicine

1 August 2017

1 reference

1 August 2017

207

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1 August 2017

12

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1 August 2017

2581-2594

1 reference

describes a project that uses

1 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2989761/fullTextXML

inferred from PubMed Central ID database lookup

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Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.

6 July 2018

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Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia

6 July 2018

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Acquired copy number alterations in adult acute myeloid leukemia genomes

6 July 2018

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The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer

6 July 2018

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High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples

6 July 2018

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PML-RARalpha initiates leukemia by conferring properties of self-renewal to committed promyelocytic progenitors

6 July 2018

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Hidden abnormalities and novel classification of t(15;17) acute promyelocytic leukemia (APL) based on genomic alterations

6 July 2018

1 reference

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Distinct thresholds govern Myc's biological output in vivo

6 July 2018

1 reference

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Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency

6 July 2018

1 reference

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Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

6 July 2018

1 reference

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Modelling Myc inhibition as a cancer therapy

6 July 2018

1 reference

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Amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer.

6 July 2018

1 reference

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FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells

6 July 2018

1 reference

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Inhibition of phosphatidylinositol 3-kinase destabilizes Mycn protein and blocks malignant progression in neuroblastoma.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

c-Myc, genome instability, and tumorigenesis: the devil is in the details.

6 July 2018

1 reference

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MYC levels govern hematopoietic tumor type and latency in transgenic mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Transcriptional regulation and transformation by Myc proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Disruption of cooperation between Ras and MycN in human neuroblastoma cells promotes growth arrest

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

A conserved element in Myc that negatively regulates its proapoptotic activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

The life cycle of C-myc: from synthesis to degradation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Direct activation of HSP90A transcription by c-Myc contributes to c-Myc-induced transformation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

CCAAT/Enhancer binding proteins repress the leukemic phenotype of acute myeloid leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

6 July 2018

Focus on acute leukemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the Unite

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Regulation of c-myc expression by PDGF through Rho GTPases.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Reversible tumorigenesis by MYC in hematopoietic lineages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Nonrandom cytogenetic alterations in hepatocellular carcinoma from transgenic mice overexpressing c-Myc and transforming growth factor-alpha in the liver

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Transient excess of MYC activity can elicit genomic instability and tumorigenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Role of the histone deacetylase complex in acute promyelocytic leukaemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

A PMLRARalpha transgene initiates murine acute promyelocytic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Production of high-titer helper-free retroviruses by transient transfection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Role of the v-erbA and v-erbB oncogenes of avian erythroblastosis virus in erythroid cell transformation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Definition of regions in human c-myc that are involved in transformation and nuclear localization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

How do retroviral oncogenes induce transformation in avian erythroid cells?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Definition of the activities and properties of c-myc required to inhibit cell differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Domains of human c-myc protein required for autosuppression and cooperation with ras oncogenes are overlapping

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

Increased frequency of both total and specific monoclonal antibody producing hybridomas using a fusion partner that constitutively expresses recombinant IL-6.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989761

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

6 July 2018

2 references

https://api.crossref.org/works/10.1084%2FJEM.20091071

21 January 2018

12 December 2020

Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091071

Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091071

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091071

Gene expression profiling of pediatric acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091071

c-Myc regulates mammalian body size by controlling cell number but not cell size

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091071

MYC-containing double minutes in hematologic malignancies: evidence in favor of the episome model and exclusion of MYC as the target gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091071

Myc/p53 interactions in transgenic mouse mammary development, tumorigenesis and chromosomal instability

21 January 2018

1 reference

12 December 2020

TRIB1 overexpression in acute myeloid leukemia

1 reference

12 December 2020

Expression profiling reveals fundamental biological differences in acute myeloid leukemia with isolated trisomy 8 and normal cytogenetics

1 reference

12 December 2020

Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia. Leukemia Study Group of the Ministry of Health and Welfare (Kohseisho)

1 reference

12 December 2020

Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20091071

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference