(Q34343025)

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Mutation of tyrosine 470 of human dopamine transporter is critical for HIV-1 Tat-induced inhibition of dopamine transport and transporter conformational transitions.

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29 February 2020

Mutation of tyrosine 470 of human dopamine transporter is critical for HIV-1 Tat-induced inhibition of dopamine transport and transporter conformational transitions (English)

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29 February 2020

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29 February 2020

Rosemarie M Booze

4

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29 February 2020

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Narasimha M Midde

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29 February 2020

Xiaoqin Huang

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29 February 2020

Chang-Guo Zhan

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29 February 2020

Jun Zhu

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29 February 2020

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5 May 2013

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29 February 2020

Journal of Neuroimmune Pharmacology

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29 February 2020

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29 February 2020

4

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29 February 2020

975-987

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29 February 2020

Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding

1 reference

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6 July 2018

HIV-1 Tat protein decreases dopamine transporter cell surface expression and vesicular monoamine transporter-2 function in rat striatal synaptosomes

1 reference

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6 July 2018

Prefrontal dopaminergic and enkephalinergic synaptic accommodation in HIV-associated neurocognitive disorders and encephalitis

1 reference

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6 July 2018

Cocaine and HIV-1 interplay: molecular mechanisms of action and addiction

1 reference

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6 July 2018

Drugs of abuse, dopamine, and HIV-associated neurocognitive disorders/HIV-associated dementia

1 reference

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6 July 2018

fMRI brain activation during a delay discounting task in HIV-positive adults with and without cocaine dependence

1 reference

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6 July 2018

Recombinant human immunodeficiency virus-1 transactivator of transcription1-86 allosterically modulates dopamine transporter activity.

1 reference

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6 July 2018

Current understanding of HIV-associated neurocognitive disorders pathogenesis

1 reference

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6 July 2018

The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Eradication of HIV from the brain: reasons for pause

1 reference

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6 July 2018

Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Neurocognitive impairment and medication adherence in HIV patients with and without cocaine dependence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Hyperdopaminergic tone in HIV-1 protein treated rats and cocaine sensitization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Single-molecule dynamics of gating in a neurotransmitter transporter homologue

1 reference

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6 July 2018

Human immunodeficiency virus-1 evolutionary patterns associated with pathogenic processes in the brain

1 reference

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6 July 2018

Mechanism for cocaine blocking the transport of dopamine: insights from molecular modeling and dynamics simulations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Human immunodeficiency virus (HIV) infection of human macrophages is increased by dopamine: a bridge between HIV-associated neurologic disorders and drug abuse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Attenuated neurotoxicity of the transactivation-defective HIV-1 Tat protein in hippocampal cell cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Role of Tat protein in HIV neuropathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Declined neural efficiency in cognitively stable human immunodeficiency virus patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

HIV-1 Tat protein-induced rapid and reversible decrease in [3H]dopamine uptake: dissociation of [3H]dopamine uptake and [3H]2beta-carbomethoxy-3-beta-(4-fluorophenyl)tropane (WIN 35,428) binding in rat striatal synaptosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Identification of new, well-populated amino-acid sidechain rotamers involving hydroxyl-hydrogen atoms and sulfhydryl-hydrogen atoms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Intra-accumbal Tat1-72 alters acute and sensitized responses to cocaine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Decreased brain dopamine transporters are related to cognitive deficits in HIV patients with or without cocaine abuse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Neurotoxic profiles of HIV, psychostimulant drugs of abuse, and their concerted effect on the brain: current status of dopamine system vulnerability in NeuroAIDS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

How dopamine transporter interacts with dopamine: insights from molecular modeling and simulation

1 reference

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6 July 2018

Glutamate and monoamine transporters: new visions of form and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Mechanisms of neurotransmitter release by amphetamines: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Probing dopamine transporter structure and function by Zn2+-site engineering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

HIV dementia: the role of the basal ganglia and dopaminergic systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

1H-13C nuclear magnetic resonance assignment and structural characterization of HIV-1 Tat protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Selective CXCR4 antagonism by Tat: implications for in vivo expansion of coreceptor use by HIV-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

HIV-1 Tat protein mimicry of chemokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Brownian dynamics simulation of protein-protein diffusional encounter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740080

6 July 2018

[3H]GBR 12935 binding in vivo in mouse brain: labelling of a piperazine acceptor site

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

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6 July 2018

Human immunodeficiency virus infection in the CNS and decreased dopamine availability: relationship with neuropsychological performance

1 reference

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21 January 2018

Human immunodeficiency virus type 1 in the central nervous system leads to decreased dopamine in different regions of postmortem human brains

1 reference

https://api.crossref.org/works/10.1007%2FS11481-013-9464-6

21 January 2018

NMDA receptor activation by HIV-Tat protein is clade dependent

1 reference

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Acceleration of HIV dementia with methamphetamine and cocaine

1 reference

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21 January 2018

Delineation of an endogenous zinc-binding site in the human dopamine transporter

1 reference

https://api.crossref.org/works/10.1007%2FS11481-013-9464-6

21 January 2018

The prevalence and incidence of neurocognitive impairment in the HAART era.

1 reference

https://api.crossref.org/works/10.1007%2FS11481-013-9464-6

21 January 2018

Persistence of neuropsychologic deficits despite long-term highly active antiretroviral therapy in patients with HIV-related neurocognitive impairment: prevalence and risk factors

1 reference

https://api.crossref.org/works/10.1007%2FS11481-013-9464-6

21 January 2018

Decreased brain dopaminergic transporters in HIV-associated dementia patients

1 reference

https://api.crossref.org/works/10.1007%2FS11481-013-9464-6

21 January 2018

Environmental enrichment decreases cell surface expression of the dopamine transporter in rat medial prefrontal cortex

1 reference

https://api.crossref.org/works/10.1007%2FS11481-013-9464-6

21 January 2018

Detection of the human immunodeficiency virus regulatory protein tat in CNS tissues

1 reference

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1 reference

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27 October 2018

Human immunodeficiency virus-associated neurocognitive disorders: Mind the gap

1 reference

https://pubmed.ncbi.nlm.nih.gov/23645138

12 December 2020

based on heuristic

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HOLLOW: generating accurate representations of channel and interior surfaces in molecular structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/23645138

12 December 2020

based on heuristic

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Detection of HIV-1 Tat and JCV capsid protein, VP1, in AIDS brain with progressive multifocal leukoencephalopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23645138

12 December 2020

based on heuristic

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10.1007/S11481-013-9464-6

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Europe PubMed Central

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29 February 2020

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24 November 2022

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29 February 2020

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29 February 2020

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