(Q34351633)

1 August 2017

title

Clinically approved iron chelators influence zebrafish mortality, hatching morphology and cardiac function (English)

1 reference

Jayachandran N Kizhakkedathu

1 August 2017

0 references

6

object named as

Jayachandran N Kizhakkedathu

1 reference

1 August 2017

Jasmine L Hamilton

1

1 reference

1 August 2017

Azadeh Hatef

2

1 reference

1 August 2017

Muhammad Imran ul-Haq

3

1 reference

1 August 2017

Neelima Nair

4

1 reference

1 August 2017

Suraj Unniappan

5

1 reference

1 August 2017

language of work or name

English

0 references

publication date

16 October 2014

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1 August 2017

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1 August 2017

volume

9

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1 August 2017

issue

10

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1 August 2017

page(s)

e109880

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Creative Commons Attribution 4.0 International

1 August 2017

copyright license

start time

16 October 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Design of iron chelators with therapeutic application

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Deferasirox: pharmacokinetics and clinical experience

6 July 2018

1 reference

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Systematic approaches to toxicology in the zebrafish

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Effects of deferasirox on renal function and renal epithelial cell death.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Fanconi syndrome in a patient with β-thalassemia major after using deferasirox for 27 months

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Safety issues of iron chelation therapy in patients with normal range iron stores including thalassaemia, neurodegenerative, renal and infectious diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Objectives and mechanism of iron chelation therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Ferroportin1 is required for normal iron cycling in zebrafish

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Iron-chelating therapy with the new oral agent ICL670 (Exjade).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Zebrafish as a model vertebrate for investigating chemical toxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

In vivo drug discovery in the zebrafish

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Iron acquisition by teleost fish

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Role of deferiprone in chelation therapy for transfusional iron overload

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Transfusional iron overload and chelation therapy with deferoxamine and deferiprone (L1).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Sensorimotor neurotoxicity associated with high-dose deferoxamine treatment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Iron-chelating therapy and the treatment of thalassemia.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Assessment of the developmental toxicity of deferoxamine in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Acute iron poisoning. A review

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Permeability of small nonelectrolytes through lipid bilayer membranes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Effective chelation of iron in beta thalassaemia with the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Deferasirox in iron-overloaded patients with transfusion-dependent myelodysplastic syndromes: Results from the large 1-year EPIC study

6 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109880

Exploring the "iron shuttle" hypothesis in chelation therapy: effects of combined deferoxamine and deferiprone treatment in hypertransfused rats with labeled iron stores and in iron-loaded rat heart cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109880

Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109880

Developmental toxicity of metal chelating agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109880

Organization and expression analysis of the zebrafish hepcidin gene, an antimicrobial peptide gene conserved among vertebrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109880

Complex Formation of ICL670 and Related Ligands with FeIIIand FeII

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109880

Dietary iron alters waterborne copper-induced gene expression in soft water acclimated zebrafish (Danio rerio).

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0109880

Estimation of permeability by passive diffusion through Caco-2 cell monolayers using the drugs' lipophilicity and molecular weight

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4199627

Chemical screening in zebrafish for novel biological and therapeutic discovery

27 October 2018

1 reference

12 December 2020

Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish

1 reference

12 December 2020

Effect of iron on the growth rate of fishes

1 reference

12 December 2020

Long-term desferrioxamine therapy in thalassemia

1 reference

12 December 2020

Toxicity of oral iron chelator L1

1 reference

12 December 2020

Survival in medically treated patients with homozygous beta-thalassemia

1 reference

12 December 2020

The relationship of intracellular iron chelation to the inhibition and regeneration of human ribonucleotide reductase

1 reference

12 December 2020

Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes

1 reference

12 December 2020

Discontinuing prophylactic transfusions used to prevent stroke in sickle cell disease

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0109880

Identifiers

DOI

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1 August 2017

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1 August 2017

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