(Q34353587)

1 August 2017

title

Induction of nitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells (English)

1 reference

1 August 2017

Sarah A Compton

1

1 reference

1 August 2017

Lynne W Elmore

2

1 reference

1 August 2017

Kimberly Haydu

3

1 reference

1 August 2017

Colleen K Jackson-Cook

4

1 reference

1 August 2017

Shawn E Holt

5

1 reference

1 August 2017

language of work or name

English

0 references

publication date

1 February 2006

1 reference

Molecular and Cellular Biology

1 August 2017

published in

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1 August 2017

volume

26

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1 August 2017

issue

4

1 reference

1 August 2017

page(s)

1452-1462

1 reference

describes a project that uses

1 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1367181/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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A DNA damage checkpoint response in telomere-initiated senescence

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THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

6 July 2018

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The Hsp90 chaperone complex as a novel target for cancer therapy

6 July 2018

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Inhibition of telomerase activity by geldanamycin and 17-allylamino, 17-demethoxygeldanamycin in human melanoma cells

6 July 2018

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Inhibition of heat shock protein 90 (hsp90) in proliferating endothelial cells uncouples endothelial nitric oxide synthase activity

6 July 2018

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6 July 2018

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Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert.

6 July 2018

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The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

6 July 2018

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Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis.

6 July 2018

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Stable association of hsp90 and p23, but Not hsp70, with active human telomerase

6 July 2018

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Hydroxyl radical-induced apoptosis in human tumor cells is associated with telomere shortening but not telomerase inhibition and caspase activation

6 July 2018

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Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase

6 July 2018

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Clonal heterogeneity in telomerase activity and telomere length in tumor-derived cell lines

6 July 2018

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Telomerase inhibition by peptide nucleic acids reverses 'immortality' of transformed human cells

6 July 2018

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Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

6 July 2018

1 reference

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DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90

6 July 2018

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Functional requirement of p23 and Hsp90 in telomerase complexes

6 July 2018

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6 July 2018

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Metastatic sublines of an SV40 large T antigen immortalized human prostate epithelial cell line

6 July 2018

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Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

6 July 2018

1 reference

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A survey of telomerase activity in human cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

Neuronal nitric oxide synthase, a modular enzyme formed by convergent evolution: structure studies of a cysteine thiolate-liganded heme protein that hydroxylates L-arginine to produce NO. as a cellular signal.

6 July 2018

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Tumorigenicity of SV40 T antigen immortalized human prostate epithelial cells: association with decreased epidermal growth factor receptor (EGFR) expression

6 July 2018

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Heat-shock protein hsp90 governs the activity of pp60v-src kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

The RNA component of human telomerase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

Origin of Concatemeric T7DNA

6 July 2018

1 reference

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Nucleotide sequence and regulation of a human 90-kDa heat shock protein gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

Reduced levels of hsp90 compromise steroid receptor action in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

Replicative senescence: the human fibroblast comes of age.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

The two-stage mechanism controlling cellular senescence and immortalization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

Adriamycin-induced senescence in breast tumor cells involves functional p53 and telomere dysfunction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

Perferryl complex of nitric oxide synthase: role in secondary free radical formation

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

A novel mechanism for chaperone-mediated telomerase regulation during prostate cancer progression

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

Telomerase activity reconstituted in vitro with purified human telomerase reverse transcriptase and human telomerase RNA component.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

Inhibition of telomerase limits the growth of human cancer cells.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1367181

Site-specific oxidation at GG and GGG sequences in double-stranded DNA by benzoyl peroxide as a tumor promoter

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16449656

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Telomere amount and length assay

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16449656

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.26.4.1452-1462.2006

1 reference

1 August 2017

1 reference

1 August 2017

1 reference