(Q34354025)

1 August 2017

title

Accumulation of true single strand breaks and AP sites in base excision repair deficient cells (English)

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1 August 2017

Shunichi Takeda

5

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author name string

April M Luke

1

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1 August 2017

Paul D Chastain

2

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1 August 2017

Brian F Pachkowski

3

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1 August 2017

Valeriy Afonin

4

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1 August 2017

David G Kaufman

6

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1 August 2017

James A Swenberg

7

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1 August 2017

Jun Nakamura

8

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1 August 2017

language of work or name

English

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publication date

17 September 2010

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1 August 2017

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1 August 2017

volume

694

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1 August 2017

issue

1-2

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1 August 2017

page(s)

65-71

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Direct detection and quantification of abasic sites for in vivo studies of DNA damage and repair

1 August 2017

cites work

1 reference

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Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS.

6 July 2018

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PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.

6 July 2018

1 reference

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JWA regulates XRCC1 and functions as a novel base excision repair protein in oxidative-stress-induced DNA single-strand breaks

6 July 2018

1 reference

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Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair

6 July 2018

1 reference

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Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde

6 July 2018

1 reference

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Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks

6 July 2018

1 reference

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Base damage and single-strand break repair: mechanisms and functional significance of short- and long-patch repair subpathways

6 July 2018

1 reference

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Role for DNA polymerase beta in response to ionizing radiation

6 July 2018

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Mammalian single-strand break repair: mechanisms and links with chromatin

6 July 2018

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Fourth International Workgroup on Genotoxicity testing: results of the in vivo Comet assay workgroup

6 July 2018

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Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage

6 July 2018

1 reference

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Potentiation of gene targeting in human cells by expression of Saccharomyces cerevisiae Rad52

6 July 2018

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Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study

6 July 2018

1 reference

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Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time

6 July 2018

1 reference

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Measurement of DNA oxidation in human cells by chromatographic and enzymic methods

6 July 2018

1 reference

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Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress

6 July 2018

1 reference

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Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

6 July 2018

1 reference

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Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

Highly sensitive apurinic/apyrimidinic site assay can detect spontaneous and chemically induced depurination under physiological conditions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

The comet assay: a comprehensive review

6 July 2018

1 reference

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Repair of N-methylpurines in specific DNA sequences in Chinese hamster ovary cells: absence of strand specificity in the dihydrofolate reductase gene

6 July 2018

1 reference

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Formation, detection and repair of AP sites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

Selective inhibition by methoxyamine of the apurinic/apyrimidinic endonuclease activity associated with pyrimidine dimer-DNA glycosylases from Micrococcus luteus and bacteriophage T4.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

Evidence for AP site formation related to DNA-oxygen alkylation in CHO cells treated with ethylating agents

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

Principles and practice of DNA filter elution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

Factors influencing DNA migration from individual cells subjected to gel electrophoresis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

Repair of MMS-induced DNA double-strand breaks in haploid cells of Saccharomyces cerevisiae, which requires the presence of a duplicate genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

Role of DNA polymerase theta in tolerance of endogenous and exogenous DNA damage in mouse B cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

Modulation of the 5'-deoxyribose-5-phosphate lyase and DNA synthesis activities of mammalian DNA polymerase beta by apurinic/apyrimidinic endonuclease 1.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

Sensitivity of the FPG protein towards alkylation damage in the comet assay.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

Synthesis and characterization of oligodeoxynucleotides containing formamidopyrimidine lesions and nonhydrolyzable analogues

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

5'-nicked apurinic/apyrimidinic sites are resistant to beta-elimination by beta-polymerase and are persistent in human cultured cells after oxidative stress.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

The International Comet Assay Workshop.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992575

Selective reaction of methoxyamine with cytosine bases in tyrosine transfer ribonucleic acid

27 October 2018

1 reference

12 December 2020

Mechanism of DNA strand breakage by piperidine at sites of N7-alkylguanines

1 reference

12 December 2020

Protocol for the quantitative assessment of DNA concentration and damage (fragmentation and nicks)

1 reference

12 December 2020

Two expressed human genes sustain slightly more DNA damage after alkylating agent treatment than an inactive gene

1 reference

12 December 2020

Protection against methylation-induced cytotoxicity by DNA polymerase beta-dependent long patch base excision repair

1 reference

12 December 2020

DNA excision repair profiles of normal and leukemic human lymphocytes: functional analysis at the single-cell level

1 reference

12 December 2020

10.1016/J.MRFMMM.2010.08.008

Identifiers

DOI

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1 August 2017

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1 August 2017

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