(Q34355252)

1 August 2017

1 reference

title

Gene identification in Alzheimer's disease (English)

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1 August 2017

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Saunders AM

1

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1 August 2017

publication date

1 August 2001

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1 August 2017

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1 August 2017

volume

2

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1 August 2017

issue

3

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1 August 2017

page(s)

239-249

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Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset.

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

A familial Alzheimer's disease locus on chromosome 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Alzheimer's disease and apolipoprotein E-4 allele in an Amish population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Complete genomic screen in late-onset familial Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

A full genome scan for late onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Molecular genetics of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Alzheimer's disease: a central role for amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Mapping of a gene predisposing to early-onset Alzheimer's disease to chromosome 14q24.3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Presenilins and Alzheimer's disease: biological functions and pathogenic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Skeletal and CNS defects in Presenilin-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Apolipoprotein E alleles as risk factors in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Alzheimer's disease and possible gene interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Onset of dementia is associated with apolipoprotein E epsilon4 in Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Relation of age and apolipoprotein E to cognitive function in Down syndrome adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

ApoE genotype and Alzheimer's disease in adults with Down syndrome: meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Amyloid angiopathy in a Volga German family with Alzheimer's disease and a presenilin-2 mutation (N141I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Apolipoprotein E and Alzheimer disease: an update on genetic and functional analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Tau pathology in two Dutch families with mutations in the microtubule-binding region of tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Genetic dissection of complex traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Association and linkage: complementary strategies for complex disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Genetic studies on chromosome 12 in late-onset Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Genetic association studies between dementia of the Alzheimer's type and three receptors for apolipoprotein E in a Caucasian population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Alpha-2 macroglobulin is genetically associated with Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Susceptibility locus for Alzheimer's disease on chromosome 10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Alzheimer's disease and HLA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

HLA-DR antigens associated with major genetic risk for late-onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Evidence for association of HLA-A2 allele with onset age of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Computerized self-assessment in psychiatric in-patients: acceptability, feasibility and influence of computer attitude.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

HLA A2 allele is associated with age at onset of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Risk for Alzheimer's disease in older late-onset cases is associated with HLA-DRB1*03.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Association of interleukin-1 gene polymorphisms with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Lack of association of the interleukin-1alpha gene polymorphism with Alzheimer's disease in a Korean population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Inflammation and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Frontotemporal dementia and parkinsonism linked to chromosome 17: a consensus conference. Conference Participants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

A stop-codon mutation in the BRI gene associated with familial British dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

CADASIL: hereditary arteriopathy leading to multiple brain infarcts and dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Prions and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Epidemiology. Tracking the human fallout from 'mad cow disease'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Signal transduction through prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Binding partners of Alzheimer's disease proteins: are they physiologically relevant?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Reelin is a ligand for lipoprotein receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

The use of single nucleotide polymorphisms in the isolation of common disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Apolipoprotein E genotype and gender influence response to tacrine therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Effect of gender and apolipoprotein E genotype on response to anticholinesterase therapy in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

The apolipoprotein E epsilon4 allele and the response to tacrine therapy in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Donepezil therapy in clinical practice: a randomized crossover study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

Identification of Novel Genes in Late-Onset Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.2.3.239

21 January 2018

Identifiers

DOI

10.1517/14622416.2.3.239

1 reference

1 August 2017

1 reference