(Q34358670)

1 August 2017

title

LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway (English)

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1 August 2017

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6

Donald E Ingber

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1 August 2017

7

Akiko Mammoto

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1 August 2017

1

Tadanori Mammoto

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1 August 2017

5

Lois E Smith

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1 August 2017

3

Elisabeth Jiang

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1 August 2017

4

Amanda Jiang

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1 August 2017

Jing Chen

2

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1 August 2017

language of work or name

English

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publication date

25 July 2012

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1 August 2017

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1 August 2017

volume

7

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1 August 2017

issue

7

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1 August 2017

page(s)

e41596

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Creative Commons Attribution 4.0 International

1 August 2017

copyright license

start time

25 July 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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How do angiopoietins Tie in with vascular endothelial growth factors?

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Hyperoxia-induced neonatal rat lung injury involves activation of TGF-{beta} and Wnt signaling and is protected by rosiglitazone

6 July 2018

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6 July 2018

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Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system

6 July 2018

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6 July 2018

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6 July 2018

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Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo

6 July 2018

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6 July 2018

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6 July 2018

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Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Wnt/beta-catenin signaling in development and disease

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Hyperoxia modulates TGF-beta/BMP signaling in a mouse model of bronchopulmonary dysplasia

6 July 2018

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Structural aspects of postnatal lung development - alveolar formation and growth

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Wnt signalling in lung development and diseases

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Vascular endothelial growth factor co-ordinates proper development of lung epithelium and vasculature

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5.

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Efficiency of transduction of highly purified murine hematopoietic stem cells by lentiviral and oncoretroviral vectors under conditions of minimal in vitro manipulation.

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Lung vascular development: implications for the pathogenesis of bronchopulmonary dysplasia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Developmental biology of the pulmonary circulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Mechanisms and limits of induced postnatal lung growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Wnt signaling and pulmonary fibrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

The role of vascular growth factors in hyperoxia-induced injury to the developing lung

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Respiratory health in a total very low birthweight cohort and their classroom controls

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

Bronchopulmonary dysplasia: "a vascular hypothesis".

6 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041596

Angiogenic factors and alveolar vasculature: development and alterations by injury in very premature baboons

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041596

Expression of genes involved in vascular development and angiogenesis in endothelial cells of adult lung.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041596

Increased expression of angiopoietins and Tie2 in the lungs of chronic asthmatic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041596

Angiopoietins contribute to lung development by regulating pulmonary vascular network formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041596

Inhibition of vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis by the Kruppel-like factor KLF2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041596

The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041596

Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041596

Effects of neonatal high-dose short-term glucocorticoid treatment on the lung: a morphologic and morphometric study in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0041596

Wnt7b regulates mesenchymal proliferation and vascular development in the lung.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

EMAP II: a modulator of neovascularization in the developing lung.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404972

The angiopoietins: Yin and Yang in angiogenesis

27 October 2018

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12 December 2020

Inhibition of vascular endothelial growth factor receptors causes emphysema in rats

1 reference

12 December 2020

Inhibition of angiogenesis decreases alveolarization in the developing rat lung

1 reference

12 December 2020

Role of oxygen and vascular development in epithelial branching morphogenesis of the developing mouse lung

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12 December 2020

Human lung growth in late gestation and in the neonate

1 reference

12 December 2020

Airway angiopoietin-2 in ventilated very preterm infants: association with prenatal factors and neonatal outcome

1 reference

12 December 2020

Increased vascularization in mice overexpressing angiopoietin-1

1 reference

12 December 2020

Angiopoietin 2 concentrations in infants developing bronchopulmonary dysplasia: attenuation by dexamethasone

1 reference

12 December 2020

Evidence for intussusceptive capillary growth in the chicken chorio-allantoic membrane (CAM)

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12 December 2020

Vascular morphogenesis and remodeling in a model of tissue repair: blood vessel formation and growth in the ovarian pedicle after ovariectomy

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0041596

Identifiers

DOI

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1 August 2017

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1 August 2017

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