(Q34361155)

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Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906667%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET (English)

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6 March 2020

pharmacokinetics

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inferred from title

Jacob M. Hooker

2

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6 March 2020

Joanna S. Fowler

11

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Joanna S Fowler

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6 March 2020

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Nora D Volkow

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6 March 2020

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Lisa Muench

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6 March 2020

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Alicia E Reid

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6 March 2020

8

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Payton King

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6 March 2020

7

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Pauline Carter

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6 March 2020

6

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Colleen Shea

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6 March 2020

author name string

Sung Won Kim

1

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6 March 2020

Nicola Otto

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6 March 2020

Khaing Win

4

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6 March 2020

publication date

29 July 2013

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6 March 2020

Nuclear Medicine and Biology

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6 March 2020

40

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6 March 2020

7

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Europe PubMed Central

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6 March 2020

912-918

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906667%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Drug treatment for spinal muscular atrophy types II and III

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Valproic acid and sodium valproate for neuropathic pain and fibromyalgia in adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

The inhibition of histone deacetylases reduces the reinstatement of cocaine-seeking behavior in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Combined treatment with the mood stabilizers lithium and valproate produces multiple beneficial effects in transgenic mouse models of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Sodium butyrate inhibits the self-renewal capacity of endometrial tumor side-population cells by inducing a DNA damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Sodium butyrate improves memory function in an Alzheimer's disease mouse model when administered at an advanced stage of disease progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Posttraining systemic administration of the histone deacetylase inhibitor sodium butyrate ameliorates aging-related memory decline in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Histone H4 acetylation by immunohistochemistry and prognosis in newly diagnosed adult acute lymphoblastic leukemia (ALL) patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Effect of butyrate enemas on inflammation and antioxidant status in the colonic mucosa of patients with ulcerative colitis in remission.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Valproic acid in pregnancy: how much are we endangering the embryo and fetus?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

3,3'-diindolylmethane enhances the efficacy of butyrate in colon cancer prevention through down-regulation of survivin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

HDAC2 negatively regulates memory formation and synaptic plasticity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Reinvestigation of the synthesis and evaluation of [N-methyl-(11)C]vorozole, a radiotracer targeting cytochrome P450 aromatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Recovery of learning and memory is associated with chromatin remodelling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Pulsed-dosing with oral sodium phenylbutyrate increases hemoglobin F in a patient with sickle cell anemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

A randomized, placebo-controlled, multicenter study of divalproex sodium extended release in the treatment of acute mania.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

The histone deacetylase (HDAC) inhibitor valproic acid as monotherapy or in combination with all-trans retinoic acid in patients with acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Depletion of latent HIV-1 infection in vivo: a proof-of-concept study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Treatment of spinal muscular atrophy by sodium butyrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Butyrate inhibits inflammatory responses through NFkappaB inhibition: implications for Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Butyrate production from dietary fibre and protection against large bowel cancer in a rat model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Induction of fetal hemoglobin production in subjects with sickle cell anemia by oral sodium phenylbutyrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

New uses of anticonvulsant drugs in psychosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Dose-dependent inhibition in plasma protein binding of valproic acid during continued treatment in guinea-pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

6 July 2018

Phenylbutyrate suppresses distinct skin reactions that are enhanced by blockade of epidermal growth factor receptor signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Sodium phenylbutyrate ameliorates focal cerebral ischemic/reperfusion injury associated with comorbid type 2 diabetes by reducing endoplasmic reticulum stress and DNA fragmentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Histone deacetylase inhibition decreases preference without affecting aversion for nicotine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Phenylbutyrate ameliorates cognitive deficit and reduces tau pathology in an Alzheimer's disease mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Influence of valproic acid on outcome of high-grade gliomas in children.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Phase 2 study of sodium phenylbutyrate in ALS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Phenylbutyrate interferes with the Fanconi anemia and BRCA pathway and sensitizes head and neck cancer cells to cisplatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Effect of time, injury, age and ethanol on interpatient variability in valproic acid pharmacokinetics after traumatic brain injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Valproic acid-induced hepatopathy: nine new fatalities in Germany from 1994 to 2003.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Valproic acid potentiates both typical and atypical antipsychotic-induced prefrontal cortical dopamine release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Pharmacokinetics of 5-azacitidine administered with phenylbutyrate in patients with refractory solid tumors or hematologic malignancies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Valproic acid and interferon-alpha synergistically inhibit neuroblastoma cell growth in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Valproate unbound fraction and distribution volume following rapid infusions in patients with epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Induction of fetal hemoglobin synthesis in children with sickle cell anemia on low-dose oral sodium phenylbutyrate therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Fatal cardiac malformation in fetal valproate syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Butyrate enema therapy stimulates mucosal repair in experimental colitis in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Butyrate derivatives. New agents for stimulating fetal globin production in the beta-globin disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Transplacental passage and half-life of sodium valproate in infants born to epileptic mothers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3769509

27 October 2018

Increased fetal hemoglobin in patients receiving sodium 4-phenylbutyrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/23906667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral sodium phenylbutyrate therapy in homozygous beta thalassemia: a clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/23906667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of interferon antitumor action by sodium butyrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/23906667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacology of sodium butyrate in patients with acute leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23906667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma concentrations of sodium valproate: their clinical value

1 reference

https://pubmed.ncbi.nlm.nih.gov/23906667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased fetal hemoglobin production in patients receiving valproic acid for epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23906667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human brain, plasma, and cerebrospinal fluid concentration of sodium valproate after 72 hours of therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23906667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valproic acid and augmentation of fetal hemoglobin in individuals with and without sickle cell disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23906667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of butyrate on induction and action of interferon

1 reference

https://pubmed.ncbi.nlm.nih.gov/23906667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of histone deacetylation in vivo and in vitro by sodium butyrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/23906667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/23906667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.NUCMEDBIO.2013.06.007

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906667%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906667%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23906667%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

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