(Q46162286)

20 December 2017

title

Phenylbutyrate ameliorates cognitive deficit and reduces tau pathology in an Alzheimer's disease mouse model (English)

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20 December 2017

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2

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20 December 2017

Ana García-Osta

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20 December 2017

Alberto Pérez-Mediavilla

object named as

Alberto Pérez-Mediavilla

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author name string

Ana Ricobaraza

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20 December 2017

Diana Frechilla

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20 December 2017

Joaquin Del Río

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20 December 2017

language of work or name

English

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publication date

14 January 2009

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20 December 2017

published in

Neuropsychopharmacology

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20 December 2017

volume

34

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20 December 2017

page(s)

1721-1732

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20 December 2017

issue

7

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20 December 2017

https://scigraph.springernature.com/pub.10.1038/npp.2008.229

exact match

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cites work

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Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses

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Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals.

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The persistence of long-term memory: a molecular approach to self-sustaining changes in learning-induced synaptic growth

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Pharmacokinetics and cerebrospinal fluid penetration of phenylacetate and phenylbutyrate in the nonhuman primate

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Neuropathological stageing of Alzheimer-related changes

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The histone deacetylase inhibitor valproic acid enhances acquisition, extinction, and reconsolidation of conditioned fear

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Treatment of spinal muscular atrophy by sodium butyrate

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Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

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Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice

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Recovery of learning and memory is associated with chromatin remodelling

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Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease.

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Histone deacetylase inhibitors improve learning consolidation in young and in KA-induced-neurodegeneration and SAMP-8-mutant mice

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Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease

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Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment

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Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau

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7 January 2021

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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7 January 2021

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

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7 January 2021

Pyrrolidine dithiocarbamate activates Akt and improves spatial learning in APP/PS1 mice without affecting beta-amyloid burden.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

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7 January 2021

Sodium 4-phenylbutyrate protects against cerebral ischemic injury.

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7 January 2021

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7 January 2021

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

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7 January 2021

Sodium 4-phenylbutyrate downregulates Hsc70: implications for intracellular trafficking of DeltaF508-CFTR

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https://api.crossref.org/works/10.1038%2FNPP.2008.229

7 January 2021

Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice

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https://api.crossref.org/works/10.1038%2FNPP.2008.229

7 January 2021

Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation

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7 January 2021

The language of covalent histone modifications

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7 January 2021

Targeting the CREB pathway for memory enhancers

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https://api.crossref.org/works/10.1038%2FNPP.2008.229

7 January 2021

Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation

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https://api.crossref.org/works/10.1038%2FNPP.2008.229

7 January 2021

Gene expression profile analysis of 4-phenylbutyrate treatment of IB3-1 bronchial epithelial cell line demonstrates a major influence on heat-shock proteins

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7 January 2021

Identifiers

DOI

10.1038/NPP.2008.229

1 reference

20 December 2017

PubMed ID

19145227

1 reference

20 December 2017