(Q34368617)

1 August 2017

title

Randomized phase I trials of the safety/tolerability of anti-LINGO-1 monoclonal antibody BIIB033 (English)

1 reference

1 August 2017

main subject

phase I clinical trial

0 references

1 reference

1 reference

3

Frederik Barkhof

1 reference

1 August 2017

Jonathan Q Tran

1

1 reference

1 August 2017

Jitesh Rana

2

1 reference

1 August 2017

Isaac Melamed

4

1 reference

1 August 2017

Hakop Gevorkyan

5

1 reference

1 August 2017

Mike P Wattjes

6

1 reference

1 August 2017

Remko de Jong

7

1 reference

1 August 2017

Kristin Brosofsky

8

1 reference

1 August 2017

Soma Ray

9

1 reference

1 August 2017

Lei Xu

10

1 reference

1 August 2017

Jim Zhao

11

1 reference

1 August 2017

Edward Parr

12

1 reference

1 August 2017

Diego Cadavid

13

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1 August 2017

publication date

21 August 2014

1 reference

Neurology(R) neuroimmunology & neuroinflammation

1 August 2017

published in

1 reference

1 August 2017

volume

1

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1 August 2017

issue

2

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1 August 2017

page(s)

e18

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Blocking LINGO-1 as a therapy to promote CNS repair: from concept to the clinic

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4202679

Methodology of diffusion-weighted, diffusion tensor and magnetisation transfer imaging

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4202679

Monoclonal antibodies: what are the pharmacokinetic and pharmacodynamic considerations for drug development?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4202679

Emerging functions of myelin-associated proteins during development, neuronal plasticity, and neurodegeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4202679

Population Pharmacokinetics of Therapeutic Monoclonal Antibodies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4202679

Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4202679

LINGO-1 negatively regulates myelination by oligodendrocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4202679

LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4202679

Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4202679

Exposure levels of anti-LINGO-1 Li81 antibody in the central nervous system and dose-efficacy relationships in rat spinal cord remyelination models after systemic administration.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4202679

Rituximab levels in cerebrospinal fluid of patients with neurological autoimmune disorders.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4202679

LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4202679

NGF regulates the expression of axonal LINGO-1 to inhibit oligodendrocyte differentiation and myelination

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25340070

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

LINGO-1 antagonists as therapy for multiple sclerosis: in vitro and in vivo evidence

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25340070

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1212/NXI.0000000000000018

1 reference

1 August 2017

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1 August 2017

1 reference