(Q34375157)

1 August 2017

title

ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex (English)

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1 August 2017

Mélina L Heuzé

1

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Joan W. Conaway

object named as

Joan W Conaway

4

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author name string

Florence C Guibal

2

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1 August 2017

Charles A Banks

3

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1 August 2017

Ronald C Conaway

5

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1 August 2017

Yvon E Cayre

6

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1 August 2017

Arndt Benecke

7

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1 August 2017

Pierre G Lutz

8

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1 August 2017

language of work or name

English

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publication date

8 December 2004

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Journal of Biological Chemistry

1 August 2017

published in

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1 August 2017

volume

280

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1 August 2017

issue

7

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1 August 2017

page(s)

5468-5474

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Translocations of the RARalpha gene in acute promyelocytic leukemia

1 August 2017

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A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage

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Lymphohematopoietic progenitors immortalized by a retroviral vector harboring a dominant-negative retinoic acid receptor can recapitulate lymphoid, myeloid, and erythroid development

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Role of the histone deacetylase complex in acute promyelocytic leukaemia

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PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells

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ASB-2 inhibits growth and promotes commitment in myeloid leukemia cells

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A function of p21 during promyelocytic leukemia cell differentiation independent of CDK inhibition and cell cycle arrest.

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UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia

21 January 2018

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C/EBPbeta: a major PML-RARA-responsive gene in retinoic acid-induced differentiation of APL cells.

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CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment

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JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells

21 January 2018

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The SOCS box: a tale of destruction and degradation

21 January 2018

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Elongin (SIII): A Multisubunit Regulator of Elongation by RNA Polymerase II

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Inhibition of Transcription Elongation by the VHL Tumor Suppressor Protein

21 January 2018

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Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C

21 January 2018

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Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

21 January 2018

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The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

21 January 2018

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The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

21 January 2018

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Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase

21 January 2018

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Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase

21 January 2018

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Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

21 January 2018

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The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity

21 January 2018

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Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

21 January 2018

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Elongin BC complex prevents degradation of von Hippel-Lindau tumor suppressor gene products

21 January 2018

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Expression of VACM-1 protein in cultured rat adrenal endothelial cells is linked to the cell cycle

21 January 2018

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VACM-1, a cul-5 gene, inhibits cellular growth by a mechanism that involves MAPK and p53 signaling pathways

21 January 2018

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Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

21 January 2018

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Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery

21 January 2018

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CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein

21 January 2018

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Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

21 January 2018

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Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression

21 January 2018

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Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

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Stem cell repopulation efficiency but not pool size is governed by p27(kip1).

21 January 2018

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SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

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p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

21 January 2018

1 reference

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p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

21 January 2018

1 reference

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The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.

21 January 2018

1 reference

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Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M413040200

1 reference

1 August 2017

1 reference