(Q34375208)

1 August 2017

title

The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation (English)

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1 August 2017

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Swee Heng Milon Pang

5

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Michael Inouye

Michael Inouye

4

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Philip D Hodgkin

Philip D Hodgkin

14

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David M Tarlinton

David M Tarlinton

12

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Stephen L. Nutt

Stephen L Nutt

15

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Herbert C. Morse

Herbert C Morse

11

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Lynn M. Corcoran

13

Lynn M Corcoran

1 reference

1 August 2017

Sebastian Carotta

1

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1 August 2017

Simon N Willis

2

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1 August 2017

Jhagvaral Hasbold

3

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1 August 2017

Dianne Emslie

6

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1 August 2017

Amanda Light

7

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1 August 2017

Michael Chopin

8

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1 August 2017

Wei Shi

9

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1 August 2017

Hongsheng Wang

10

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1 August 2017

language of work or name

English

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publication date

6 October 2014

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Journal of Experimental Medicine

1 August 2017

published in

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1 August 2017

volume

211

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1 August 2017

issue

11

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1 August 2017

page(s)

2169-2181

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describes a project that uses

1 August 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4203955

inferred from PubMed Central ID database lookup

cites work

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A reporter mouse reveals lineage-specific and heterogeneous expression of IRF8 during lymphoid and myeloid cell differentiation

6 July 2018

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Transcription factor IRF4 regulates germinal center cell formation through a B cell-intrinsic mechanism

6 July 2018

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Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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IRF8 governs expression of genes involved in innate and adaptive immunity in human and mouse germinal center B cells

6 July 2018

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Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus

6 July 2018

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The genetic network controlling plasma cell differentiation

6 July 2018

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6 July 2018

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6 July 2018

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Association of a functional polymorphism in the 3'-untranslated region of SPI1 with systemic lupus erythematosus

6 July 2018

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IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools

6 July 2018

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Regulation of follicular B cell differentiation by the related E26 transformation-specific transcription factors PU.1, Spi-B, and Spi-C.

6 July 2018

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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

6 July 2018

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Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors

6 July 2018

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XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

TopHat: discovering splice junctions with RNA-Seq

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

IRF8 regulates myeloid and B lymphoid lineage diversification

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

IRF8 regulates B-cell lineage specification, commitment, and differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Plasma cell development: from B-cell subsets to long-term survival niches.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

PU.1 and ICSBP control constitutive and IFN-gamma-regulated Tlr9 gene expression in mouse macrophages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Polycomb complexes repress developmental regulators in murine embryonic stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Regulation of plasma-cell development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Plasma cell ontogeny defined by quantitative changes in blimp-1 expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Control of inflammation, cytokine expression, and germinal center formation by BCL-6

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

PU.1 is a component of a multiprotein complex which binds an essential site in the murine immunoglobulin lambda 2-4 enhancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203955

Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis.

6 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140425

Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140425

Activation-induced B cell fates are selected by intracellular stochastic competition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140425

Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140425

Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140425

A role for Blimp1 in the transcriptional network controlling natural killer cell maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140425

Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140425

Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140425

A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140425

BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140425

Blimp-1 Is Required for the Formation of Immunoglobulin Secreting Plasma Cells and Pre-Plasma Memory B Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140425

Deletion of genes encoding PU.1 and Spi-B in B cells impairs differentiation and induces pre-B cell acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140425

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20140425

Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation

21 January 2018

1 reference

12 December 2020

The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

1 reference

12 December 2020

High Rate of Antibody Secretion Is not Integral to Plasma Cell Differentiation as Revealed by XBP-1 Deficiency

1 reference

12 December 2020

Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function

1 reference

12 December 2020

Switching to IgG3, IgG2b, and IgA is division linked and independent, revealing a stochastic framework for describing differentiation

1 reference

12 December 2020

The development of functional B lymphocytes in conditional PU.1 knock-out mice

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20140425

1 reference

1 August 2017

1 reference

1 August 2017

1 reference