(Q34383447)

1 August 2017

title

Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons (English)

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1 August 2017

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mitochondrial fission

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1

Berthet A

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1 August 2017

2

Margolis EB

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1 August 2017

3

Zhang J

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1 August 2017

4

Hsieh I

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1 August 2017

5

Zhang J

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6

Hnasko TS

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7

Ahmad J

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8

Edwards RH

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9

Sesaki H

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10

Huang EJ

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Nakamura K

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ORCID Public Data File 2021

1 August 2017

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language of work or name

English

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publication date

1 October 2014

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1 August 2017

published in

Journal of Neuroscience

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1 August 2017

volume

34

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1 August 2017

issue

43

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1 August 2017

page(s)

14304-14317

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Energy failure: does it contribute to neurodegeneration?

1 August 2017

cites work

1 reference

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α-Synuclein and mitochondria: partners in crime?

6 July 2018

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Vesicular glycolysis provides on-board energy for fast axonal transport

6 July 2018

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Mitochondrial dynamics in neurodegeneration

6 July 2018

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Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit

6 July 2018

1 reference

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Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage

6 July 2018

1 reference

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Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

6 July 2018

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6 July 2018

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LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

6 July 2018

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v-SNARE composition distinguishes synaptic vesicle pools.

6 July 2018

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Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli

6 July 2018

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Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein

6 July 2018

1 reference

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PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease

6 July 2018

1 reference

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Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease

6 July 2018

1 reference

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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

6 July 2018

1 reference

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Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1.

6 July 2018

1 reference

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Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

6 July 2018

1 reference

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In vitro identification and electrophysiological characterization of dopamine neurons in the ventral tegmental area

6 July 2018

1 reference

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Clinical progression in Parkinson disease and the neurobiology of axons.

6 July 2018

1 reference

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Pacemaking in dopaminergic ventral tegmental area neurons: depolarizing drive from background and voltage-dependent sodium conductances

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo.

6 July 2018

1 reference

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A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Conversion of red fluorescent protein into a bright blue probe

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

The PINK1/Parkin pathway regulates mitochondrial morphology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

'Rejuvenation' protects neurons in mouse models of Parkinson's disease

6 July 2018

1 reference

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Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons

6 July 2018

1 reference

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Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons

6 July 2018

1 reference

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Cre recombinase-mediated restoration of nigrostriatal dopamine in dopamine-deficient mice reverses hypophagia and bradykinesia

6 July 2018

1 reference

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Kappa opioids selectively control dopaminergic neurons projecting to the prefrontal cortex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Ca(2+) homeostasis during mitochondrial fragmentation and perinuclear clustering induced by hFis1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Immunochemical analysis of dopamine transporter protein in Parkinson's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Midbrain dopaminergic neurons in the mouse: co-localization with Calbindin-D28K and calretinin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Intracellular transport in neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Ultrastructure of spared dopamine terminals in caudate-putamen nuclei of adult rats neonatally treated with intranigral 6-hydroxydopamine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Pharmacological analysis demonstrates dramatic alteration of D1 dopamine receptor neuronal distribution in the rat analog of L-DOPA-induced dyskinesia

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Single nigrostriatal dopaminergic neurons form widely spread and highly dense axonal arborizations in the neostriatum.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Bax/Bak-dependent release of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and mitoptosis during programmed cell death

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Poor and protracted myelination as a contributory factor to neurodegenerative disorders

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

I(h) channels contribute to the different functional properties of identified dopaminergic subpopulations in the midbrain.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Dopamine-deficient mice are hypersensitive to dopamine receptor agonists.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Haloperidol induces persistent down-regulation of tyrosine hydroxylase immunoreactivity in substantia nigra but not ventral tegmental area in the rat.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Internalization of D1 dopamine receptor in striatal neurons in vivo as evidence of activation by dopamine agonists.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Monoamine innervation of the forebrain: Collateralization

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205554

Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25339743

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.0930-14.2014

1 reference

1 August 2017

1 reference

1 August 2017

1 reference