(Q34384331)

1 August 2017

title

Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses (English)

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1 August 2017

9

Thomas G Ksiazek

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1 August 2017

Bin Gong

1

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1 August 2017

Thomas Shelite

2

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1 August 2017

Fang C Mei

3

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1 August 2017

Tuha Ha

4

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1 August 2017

Yaohua Hu

5

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1 August 2017

Guang Xu

6

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1 August 2017

Qing Chang

7

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1 August 2017

Maki Wakamiya

8

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1 August 2017

Paul J Boor

10

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1 August 2017

Donald H Bouyer

11

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1 August 2017

Vsevolod L Popov

12

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1 August 2017

Ju Chen

13

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1 August 2017

David H Walker

14

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1 August 2017

Xiaodong Cheng

15

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1 August 2017

language of work or name

English

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publication date

11 November 2013

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

110

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1 August 2017

issue

48

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1 August 2017

page(s)

19615-19620

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Exchange protein directly activated by cAMP (epac): a multidomain cAMP mediator in the regulation of diverse biological functions

1 August 2017

cites work

1 reference

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6 July 2018

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6 July 2018

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6 July 2018

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Isoform-specific antagonists of exchange proteins directly activated by cAMP

6 July 2018

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A novel EPAC-specific inhibitor suppresses pancreatic cancer cell migration and invasion

6 July 2018

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Effect of cellular senescence on the albumin permeability of blood-derived endothelial cells

6 July 2018

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Rickettsiae induce microvascular hyperpermeability via phosphorylation of VE-cadherins: evidence from atomic force microscopy and biochemical studies

6 July 2018

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The rickettsial OmpB β-peptide of Rickettsia conorii is sufficient to facilitate factor H-mediated serum resistance

6 July 2018

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Identification and characterization of the mammalian association and actin-nucleating domains in the Rickettsia conorii autotransporter protein, Sca2

6 July 2018

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Systemic treatment with CpG-B after sublethal rickettsial infection induces mouse death through indoleamine 2,3-dioxygenase (IDO).

6 July 2018

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PDE4 regulates tissue plasminogen activator expression of human brain microvascular endothelial cells

6 July 2018

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Rickettsia parkeri invasion of diverse host cells involves an Arp2/3 complex, WAVE complex and Rho-family GTPase-dependent pathway

6 July 2018

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Activation of GPR4 by acidosis increases endothelial cell adhesion through the cAMP/Epac pathway

6 July 2018

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The myriad roles of cyclic AMP in microbial pathogens: from signal to sword

6 July 2018

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New insight into immunity and immunopathology of Rickettsial diseases

6 July 2018

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The extent of desmoglein 3 depletion in pemphigus vulgaris is dependent on Ca(2+)-induced differentiation: a role in suprabasal epidermal skin splitting?

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Cortactin deficiency is associated with reduced neutrophil recruitment but increased vascular permeability in vivo

6 July 2018

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Adherence to and invasion of host cells by spotted Fever group rickettsia species

6 July 2018

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Cyclic AMP phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a vascular endothelial cadherin (VE-Cad)-based signaling complex and controls cAMP-mediated vascular permeability

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Rocky mountain spotted fever in the United States, 2000-2007: interpreting contemporary increases in incidence

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

The Rickettsia conorii autotransporter protein Sca1 promotes adherence to nonphagocytic mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Vascular endothelial-cadherin stabilizes at cell-cell junctions by anchoring to circumferential actin bundles through alpha- and beta-catenins in cyclic AMP-Epac-Rap1 signal-activated endothelial cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

The realities of biodefense vaccines against Rickettsia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Rickettsial outer-membrane protein B (rOmpB) mediates bacterial invasion through Ku70 in an actin, c-Cbl, clathrin and caveolin 2-dependent manner

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Emerging and re-emerging tick-transmitted rickettsial and ehrlichial infections

6 July 2018

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Warmer weather linked to tick attack and emergence of severe rickettsioses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Epac and PKA: a tale of two intracellular cAMP receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Emerging and re-emerging rickettsioses: endothelial cell infection and early disease events

6 July 2018

1 reference

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Role of Epac1, an exchange factor for Rap GTPases, in endothelial microtubule dynamics and barrier function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

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6 July 2018

1 reference

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Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Interplay between exchange protein directly activated by cAMP (Epac) and microtubule cytoskeleton

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Ku70, a component of DNA-dependent protein kinase, is a mammalian receptor for Rickettsia conorii

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Rocky Mountain spotted fever--changing ecology and persisting virulence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Early signaling events involved in the entry of Rickettsia conorii into mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Mediterranean spotted fever in Portugal: risk factors for fatal outcome in 105 hospitalized patients.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

A family of cAMP-binding proteins that directly activate Rap1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Rickettsia australis infection: a murine model of a highly invasive vasculopathic rickettsiosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3845138

Coping strategies moderate the relation of hypothalamus-pituitary-adrenal axis reactivity to self-injurious behavior

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1314400110

Cyclic nucleotide research -- still expanding after half a century

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1314400110

The Epac-Rap1 signaling pathway controls cAMP-mediated exocytosis of Weibel-Palade bodies in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1314400110

Selective inhibition of cytokine-activated extracellular signal-regulated kinase by cyclic AMP via Epac1-dependent induction of suppressor of cytokine signalling-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1314400110

Identification of CCAAT/enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1314400110

Chemical genetics: where genetics and pharmacology meet

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1314400110

Epac1 regulates integrity of endothelial cell junctions through VE-cadherin

21 January 2018

1 reference

12 December 2020

Exchange protein directly activated by cyclic AMP-1-regulated recruitment of CCAAT/enhancer-binding proteins to the suppressor of cytokine signaling-3 promoter

1 reference

12 December 2020

Improved plaque assay for Rickettsia tsutsugamushi

1 reference

12 December 2020

Both protein kinase A and exchange protein activated by cAMP coordinate adhesion of human vascular endothelial cells

1 reference

12 December 2020

Principles of the malicious use of infectious agents to create terror: reasons for concern for organisms of the genus Rickettsia

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1314400110

1 reference

1 August 2017

0 references

1 reference

1 August 2017

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