(Q34400650)

1 August 2017

1 reference

title

Transmembrane and cytoplasmic domains in integrin activation and protein-protein interactions (review). (English)

1 reference

protein-protein interaction

1 August 2017

main subject

transmembrane protein

0 references

1 reference

Kate L Wegener

1

1 reference

1 August 2017

Iain D Campbell

series ordinal

2

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1 August 2017

publication date

1 August 2008

1 reference

Molecular Membrane Biology

1 August 2017

published in

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1 August 2017

volume

25

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1 August 2017

issue

5

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1 August 2017

page(s)

376-387

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Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles

1 August 2017

cites work

1 reference

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Kindlin-3 is essential for integrin activation and platelet aggregation

6 July 2018

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Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent beta1-integrin affinity

6 July 2018

1 reference

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Coarse-grained simulation: a high-throughput computational approach to membrane proteins

6 July 2018

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An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding

6 July 2018

1 reference

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Structure and mechanics of integrin-based cell adhesion.

6 July 2018

1 reference

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Integrin cytoskeletal interactions.

6 July 2018

1 reference

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Structural basis of integrin activation by talin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Structural basis of integrin regulation and signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Integrin structures and conformational signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

The molecular basis of filamin binding to integrins and competition with talin

6 July 2018

1 reference

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The mechanisms and dynamics of (alpha)v(beta)3 integrin clustering in living cells

6 July 2018

1 reference

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Flexible nets. The roles of intrinsic disorder in protein interaction networks.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

A push-pull mechanism for regulating integrin function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Structural and evolutionary division of phosphotyrosine binding (PTB) domains.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Regulation of integrin function through conformational complexity: not simply a knee-jerk reaction?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

A specific interface between integrin transmembrane helices and affinity for ligand

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Membrane-mediated structural transitions at the cytoplasmic face during integrin activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Determination of N- and C-terminal borders of the transmembrane domain of integrin subunits

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Involvement of transmembrane domain interactions in signal transduction by alpha/beta integrins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Structural determinants of integrin recognition by talin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Characterization of the monomeric form of the transmembrane and cytoplasmic domains of the integrin beta 3 subunit by NMR spectroscopy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Three-dimensional model of the human platelet integrin alpha IIbbeta 3 based on electron cryomicroscopy and x-ray crystallography

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Integrins: bidirectional, allosteric signaling machines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Transmembrane signal transduction of the alpha(IIb)beta(3) integrin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

The phosphotyrosine binding-like domain of talin activates integrins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Oligomerization of the integrin alphaIIbbeta3: roles of the transmembrane and cytoplasmic domains

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Function and interactions of integrins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Crystal structure of the extracellular segment of integrin alpha Vbeta3

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Integrin cytoplasmic domain-binding proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

A structural basis for integrin activation by the cytoplasmic tail of the alpha IIb-subunit

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

The preference of tryptophan for membrane interfaces.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

A transmembrane helix dimer: structure and implications

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

MOLMOL: a program for display and analysis of macromolecular structures

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

The conserved membrane-proximal region of an integrin cytoplasmic domain specifies ligand binding affinity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Integrin cytoplasmic domains mediate inside-out signal transduction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

The crystal structure of the plexin-semaphorin-integrin domain/hybrid domain/I-EGF1 segment from the human integrin beta2 subunit at 1.8-A resolution.

6 July 2018

1 reference

https://api.crossref.org/works/10.1080%2F09687680802269886

Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09687680802269886

Evidence for hetero-association of transmembrane helices of integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09687680802269886

A coiled-coil structure of the alphaIIbbeta3 integrin transmembrane and cytoplasmic domains in its resting state

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09687680802269886

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09687680802269886

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09687680802269886

The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09687680802269886

Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09687680802269886

Paxillin binding to the alpha 4 integrin subunit stimulates LFA-1 (integrin alpha L beta 2)-dependent T cell migration by augmenting the activation of focal adhesion kinase/proline-rich tyrosine kinase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09687680802269886

The MIG-2/integrin interaction strengthens cell-matrix adhesion and modulates cell motility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09687680802269886

Kindlin-2 (Mig-2): a co-activator of beta3 integrins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09687680802269886

Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09687680802269886

A point mutation in the integrin beta 3 cytoplasmic domain (S752-->P) impairs bidirectional signaling through alpha IIb beta 3 (platelet glycoprotein IIb-IIIa).

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000922

Divalent Cations Differentially Regulate Integrin αIIbCytoplasmic Tail Binding to β3and to Calcium- and Integrin-binding Protein

27 October 2018

1 reference

https://api.crossref.org/works/10.1080%2F09687680802269886

The alpha subunit cytoplasmic domain regulates the assembly and adhesiveness of integrin lymphocyte function-associated antigen-1

21 January 2018

1 reference

12 December 2020

Mutation of the cytoplasmic domain of the integrin beta 3 subunit. Differential effects on cell spreading, recruitment to adhesion plaques, endocytosis, and phagocytosis

1 reference

12 December 2020

The cytoplasmic domain of alphaIIb beta3. A ternary complex of the integrin alpha and beta subunits and a divalent cation

1 reference

12 December 2020

The inner world of cell adhesion: integrin cytoplasmic domains

1 reference

12 December 2020

10.1080/09687680802269886

Identifiers

DOI

1 reference

1 August 2017

1 reference

1 August 2017

1 reference