(Q34402549)

1 August 2017

title

Use of pseudoracemic nitrendipine to elucidate the metabolic steps responsible for stereoselective disposition of nitrendipine enantiomers (English)

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1 August 2017

1 reference

1 reference

3

G. Mikus

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1540491

6 October 2022

author name string

V. Mast

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1540491

6 October 2022

C. Fischer

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1540491

6 October 2022

M. Eichelbaum

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1540491

6 October 2022

language of work or name

English

0 references

publication date

1 January 1992

1 reference

full work available at URL

1 August 2017

https://europepmc.org/articles/PMC1381199

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1540491

https://europepmc.org/articles/PMC1381199?pdf=render

6 October 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1540491

British Journal of Clinical Pharmacology

6 October 2022

published in

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1 August 2017

volume

33

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1 August 2017

issue

1

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1 August 2017

page(s)

51-59

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Stereoselective first-pass metabolism of highly cleared drugs: studies of the bioavailability of L- and D-verapamil examined with a stable isotope technique

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

6 July 2018

On chiral drug action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Mode of antihypertensive action of nitrendipine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Importance of drug enantiomers in clinical pharmacology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Nitrendipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of hypertension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Application of stable isotope methodology to study the pharmacokinetics, bioavailability and metabolism of nitrendipine after i.v. and p.o. administration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Cytochrome P-450-catalyzed hydroxylation and carboxylic acid ester cleavage of Hantzsch pyridine esters

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Stereoselectivity of bioactive xenobiotics. A pre-Pasteur attitude in medicinal chemistry, pharmacokinetics and clinical pharmacology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Nitrendipine kinetics in normal and impaired renal function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Stereoselectivity: an issue of significant importance in clinical pharmacology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Oral absorption profile of nitrendipine in healthy subjects: a kinetic and dynamic study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Stereoselectivity at the calcium channel: opposite action of the enantiomers of a 1,4-dihydropyridine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Enantiomer specific pharmacokinetics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Stereoselective inhibition of thromboxane-induced coronary vasoconstriction by 1,4-dihydropyridine calcium channel antagonists

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Nonlinear least-squares regression programs for microcomputers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381199

Studies on the relationship between chemical constitution and physiological action: Molecular dissymmetry and physiological activity

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1992.TB04000.X

The effects of nimodipine, its optical isomers and metabolites on isolated vascular smooth muscle

21 January 2018

1 reference

12 December 2020

Quantification of nitrendipine by stable isotope dilution and electron-capture negative ion chemical ionization

1 reference

12 December 2020

Stereoselective oxidation and plasma protein binding of nilvadipine, a new dihydropyridine calcium antagonist, in man

1 reference

12 December 2020

Pharmacodynamic and pharmacokinetic differences between drug enantiomers in humans: an overview

1 reference

12 December 2020

Steady-state pharmacokinetics of nitrendipine in hepatic insufficiency

1 reference

12 December 2020

Elimination and haemodynamic effects of nitrendipine in patients with chronic renal failure

1 reference

12 December 2020

Oxidative cleavage of carboxylic esters by cytochrome P-450

1 reference

12 December 2020

Bioavailability and elimination of nitrendipine in liver disease

1 reference

12 December 2020

Pharmacokinetics and metabolism of calcium-blocking agents nifedipine, nitrendipine, and nimodipine

1 reference

12 December 2020

Bioequivalence and metabolism of nitrendipine administered orally to healthy volunteers

1 reference

12 December 2020

High-performance liquid chromatography of the metabolites of nitrendipine and investigation into the metabolic pathways of this dihydropyridine

1 reference

12 December 2020

10.1111/J.1365-2125.1992.TB04000.X

Identifiers

DOI

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1 August 2017

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1 August 2017

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