(Q34417983)

English

Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis

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scholarly article

1 reference

Europe PubMed Central

2 August 2017

Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis (English)

1 reference

Europe PubMed Central

2 August 2017

1 reference

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inferred from title

author name string

Rui Liu

1

1 reference

Europe PubMed Central

2 August 2017

Cai-Xia Wu

2

1 reference

Europe PubMed Central

2 August 2017

Dan Zhou

3

1 reference

Europe PubMed Central

2 August 2017

Fan Yang

4

1 reference

Europe PubMed Central

2 August 2017

Shuo Tian

5

1 reference

Europe PubMed Central

2 August 2017

Li Zhang

6

1 reference

Europe PubMed Central

2 August 2017

Tian-Tai Zhang

7

1 reference

Europe PubMed Central

2 August 2017

Guan-Hua Du

8

1 reference

Europe PubMed Central

2 August 2017

language of work or name

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publication date

18 September 2012

1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

10

1 reference

Europe PubMed Central

2 August 2017

105

1 reference

Europe PubMed Central

2 August 2017

https://scigraph.springernature.com/pub.10.1186/1741-7015-10-105

0 references

Pinocembrin attenuates blood-brain barrier injury induced by global cerebral ischemia-reperfusion in rats.

1 reference

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6 July 2018

Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells

1 reference

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6 July 2018

RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction

1 reference

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6 July 2018

High-throughput automated confocal microscopy imaging screen of a kinase-focused library to identify p38 mitogen-activated protein kinase inhibitors using the GE InCell 3000 analyzer

1 reference

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6 July 2018

RAGE and Alzheimer's disease: a progression factor for amyloid-beta-induced cellular perturbation?

1 reference

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6 July 2018

Abeta-dependent Inhibition of LTP in different intracortical circuits of the visual cortex: the role of RAGE

1 reference

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6 July 2018

Pharmaceutical treatment for cognitive deficits in Alzheimer's disease and other neurodegenerative conditions: exploring new territory using traditional tools and established maps

1 reference

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6 July 2018

Pinocembrin prevents glutamate-induced apoptosis in SH-SY5Y neuronal cells via decrease of bax/bcl-2 ratio

1 reference

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6 July 2018

Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction.

1 reference

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6 July 2018

Study of the functional role of Bcl-2 family proteins in regulating Ca(2+) signals in apoptotic cells

1 reference

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6 July 2018

Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment

1 reference

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6 July 2018

Intracellular amyloid-beta in Alzheimer's disease

1 reference

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6 July 2018

Neuroinflammation in Alzheimer's disease: protector or promoter?

1 reference

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6 July 2018

Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase.

1 reference

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6 July 2018

Protections of pinocembrin on brain mitochondria contribute to cognitive improvement in chronic cerebral hypoperfused rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

RAGE: a journey from the complications of diabetes to disorders of the nervous system - striking a fine balance between injury and repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

Mitochondria: a target for neuroprotective interventions in cerebral ischemia-reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

Evaluation of rage isoforms, ligands, and signaling in the brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

Altered intracellular signaling and reduced viability of Alzheimer's disease neuronal cybrids is reproduced by beta-amyloid peptide acting through receptor for advanced glycation end products (RAGE).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

JNK2 translocates to the mitochondria and mediates cytochrome c release in PC12 cells in response to 6-hydroxydopamine

1 reference

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6 July 2018

RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

Alzheimer's disease is a synaptic failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

Possible mechanisms of APP-mediated oxidative stress in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

Mammalian MAP kinase signalling cascades

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

Neurotoxic Abeta peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

The biology of the receptor for advanced glycation end products and its ligands

1 reference

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6 July 2018

Astroglial expression of human alpha(1)-antichymotrypsin enhances alzheimer-like pathology in amyloid protein precursor transgenic mice

1 reference

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6 July 2018

Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration

1 reference

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6 July 2018

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

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6 July 2018

DNA damage and activated caspase-3 expression in neurons and astrocytes: evidence for apoptosis in frontotemporal dementia

1 reference

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6 July 2018

Repeated intracerebroventricular administration of beta-amyloid(25-35) to rats decreases muscarinic receptors in cerebral cortex

1 reference

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6 July 2018

Review of oxidative stress in brain and spinal cord injury: suggestions for pharmacological and nutritional management strategies

1 reference

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6 July 2018

Amyloid beta-peptide inhibits high-affinity choline uptake and acetylcholine release in rat hippocampal slices.

1 reference

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1 reference

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1 reference

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6 July 2018

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

Normal and abnormal biology of the beta-amyloid precursor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

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Developments of a water-maze procedure for studying spatial learning in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

6 July 2018

Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide.

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

21 January 2018

Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism.

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

21 January 2018

RAGE is expressed in pyramidal cells of the hippocampus following moderate hypoxic-ischemic brain injury in rats.

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

21 January 2018

Identification of metabolites in plasma and urine of Uruguayan propolis-treated rats

1 reference

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21 January 2018

Uptake characteristics of pinocembrin and its effect on p-glycoprotein at the blood-brain barrier in in vitro cell experiments.

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

21 January 2018

Pinocembrin protects rat brain against oxidation and apoptosis induced by ischemia-reperfusion both in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

21 January 2018

Acute neurovascular unit protective action of pinocembrin against permanent cerebral ischemia in rats

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

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Delayed treatment with nimesulide reduces measures of oxidative stress following global ischemic brain injury in gerbils

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1 reference

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21 January 2018

beta-Amyloid protein-induced Alzheimer's disease animal model.

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

21 January 2018

Nontoxic amyloid beta peptide 1-42 suppresses acetylcholine synthesis. Possible role in cholinergic dysfunction in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

21 January 2018

The effects of Tabernaemontana divaricata root extract on amyloid beta-peptide 25-35 peptides induced cognitive deficits in mice.

1 reference

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21 January 2018

Abeta(25-35) and Abeta(1-40) act on different calcium channels in CA1 hippocampal neurons

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

21 January 2018

Differential neuroimmune markers to the onset of Alzheimer's disease neurodegeneration and dementia: autoantibodies to Abeta((25-35)) oligomers, S100b and neurotransmitters.

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

21 January 2018

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

21 January 2018

Receptor for Advanced Glycation Endproducts (RAGE): a formidable force in the pathogenesis of the cardiovascular complications of diabetes & aging

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

21 January 2018

Assessment of the anti-inflammatory activity and free radical scavenger activity of tiliroside.

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

21 January 2018

The small heat shock protein Hsp27 protects cortical neurons against the toxic effects of beta-amyloid peptide.

1 reference

https://api.crossref.org/works/10.1186%2F1741-7015-10-105

21 January 2018

Initial studies with high resolution TEM and electron energy loss spectroscopy studies of ferritin cores extracted from brains of patients with progressive supranuclear palsy and Alzheimer disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542580

27 October 2018

RAGE: a potential target for Abeta-mediated cellular perturbation in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22989295

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Luteolin isolated from the medicinal plant Elsholtzia rugulosa (Labiatae) prevents copper-mediated toxicity in β-amyloid precursor protein Swedish mutation overexpressing SH-SY5Y cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22989295

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The characteristics of therapeutic effect of pinocembrin in transient global brain ischemia/reperfusion rats

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https://pubmed.ncbi.nlm.nih.gov/22989295

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https://pubmed.ncbi.nlm.nih.gov/22989295

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Changes in mitochondrial membrane potential during oxidative stress-induced apoptosis in PC12 cells

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https://pubmed.ncbi.nlm.nih.gov/22989295

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Alzheimer's APP mangles mitochondria

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Identifiers

10.1186/1741-7015-10-105

1 reference

Europe PubMed Central

2 August 2017

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1 reference

Europe PubMed Central

2 August 2017

1 reference

Europe PubMed Central

2 August 2017

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