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NUP98 gene fusions in hematologic malignancies.
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Europe PubMed Central
PubMed publication ID
11681408
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681408%20AND%20SRC:MED&resulttype=core&format=json
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2 December 2019
review article
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title
NUP98 gene fusions in hematologic malignancies
(English)
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Europe PubMed Central
PubMed publication ID
11681408
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681408%20AND%20SRC:MED&resulttype=core&format=json
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2 December 2019
author
Peter Aplan
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P D Aplan
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Europe PubMed Central
PubMed publication ID
11681408
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681408%20AND%20SRC:MED&resulttype=core&format=json
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2 December 2019
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D H Lam
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1
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PubMed publication ID
11681408
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2 December 2019
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1 November 2001
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11681408
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2 December 2019
published in
Leukemia
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PubMed publication ID
11681408
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2 December 2019
volume
15
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11681408
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2 December 2019
issue
11
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PubMed publication ID
11681408
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2 December 2019
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1689-1695
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11681408
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2 December 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.leu.2402269
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Translocations, master genes, and differences between the origins of acute and chronic leukemias
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Chromosomal translocations in human cancer.
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Oncogenic transcription factors in the human acute leukemias
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The critical role of chromosome translocations in human leukemias.
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Chromosome banding studies in 106 cases of chronic myelogenous leukemia
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7 January 2021
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Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia
1 reference
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reference URL
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7 January 2021
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The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9
1 reference
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Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins
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reference URL
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7 January 2021
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The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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The vertebrate GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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A conserved biogenesis pathway for nucleoporins: proteolytic processing of a 186-kilodalton precursor generates Nup98 and the novel nucleoporin, Nup96
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import
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7 January 2021
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inferred from DOI database lookup
Disruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and function
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The yeast nuclear pore complex: composition, architecture, and transport mechanism
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7 January 2021
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inferred from DOI database lookup
Transport between the cell nucleus and the cytoplasm
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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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inferred from DOI database lookup
The nucleoporin Nup98 associates with the intranuclear filamentous protein network of TPR.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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inferred from DOI database lookup
RanGTP-mediated nuclear export of karyopherin alpha involves its interaction with the nucleoporin Nup153
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
based on heuristic
inferred from DOI database lookup
Karyopherin beta2 mediates nuclear import of a mRNA binding protein
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7 January 2021
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Reconstituted nuclei depleted of a vertebrate GLFG nuclear pore protein, p97, import but are defective in nuclear growth and replication
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7 January 2021
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TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates
1 reference
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7 January 2021
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The mRNA export in Caenorhabditis elegans is mediated by Ce-NXF-1, an ortholog of human TAP/NXF and Saccharomyces cerevisiae Mex67p
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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Genomic imprinting and cancer
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Potential role for DNA topoisomerase II poisons in the generation of t(11;20)(p15;q11) translocations
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CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity
1 reference
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7 January 2021
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Heterogenous fusion transcripts involving the NUP98 gene and HOXD13 gene activation in a case of acute myeloid leukemia with the t(2;11)(q31;p15) translocation
1 reference
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reference URL
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7 January 2021
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Molecular heterogeneity of the NUP98/HOXA9 fusion transcript in myelodysplastic syndromes associated with t(7;11)(p15;p15)
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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Autoproteolysis in nucleoporin biogenesis
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7 January 2021
based on heuristic
inferred from DOI database lookup
A new family of yeast nuclear pore complex proteins
1 reference
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Crossref
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7 January 2021
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Hox genes in vertebrate development
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7 January 2021
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Paralogous Hox genes: function and regulation
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7 January 2021
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Vertebrate homeobox gene nomenclature
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A rational nomenclature for vertebrate homeobox (HOX) genes
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hox homeobox genes as regulators of normal and leukemic hematopoiesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
based on heuristic
inferred from DOI database lookup
The role of HOX homeobox genes in normal and leukemic hematopoiesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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inferred from DOI database lookup
Lineage and stage specific expression of HOX 1 genes in the human hematopoietic system
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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Synpolydactyly in mice with a targeted deficiency in the HoxD complex
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
based on heuristic
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Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular classification of cancer: class discovery and class prediction by gene expression monitoring
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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inferred from DOI database lookup
Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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Deregulation of a Homeobox Gene, HOX11, by the t(10;14) in T Cell Leukemia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
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inferred from DOI database lookup
A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical, haematological and molecular studies in patients with chromosome translocation t(7;11): a study of four Chinese patients in Taiwan
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic myelomonocytic leukemia with t(7;11)(p15;p15) and NUP98/HOXA9 fusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
based on heuristic
inferred from DOI database lookup
Low frequency of rearrangements of the homeobox gene HOXA9/t(7;11) in adult acute myeloid leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
11p15 translocations involving the NUP98 gene in childhood therapy-related acute myeloid leukemia/myelodysplastic syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the NUP98/HOXA9 fusion transcript in the blast crisis of Philadelphia chromosome-positive chronic myelogenous leukaemia with t(7;11)(p15;p15).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Down's syndrome with myelodysplastic syndrome showing t(7;11)(p13;p14)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generation of the NUP98-HOXD13 fusion transcript by a rare translocation, t(2;11)(q31;p15), in a case of infant leukaemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translocation (1;11)(q23;p15), a novel simple variant of translocation (7;11)(p15;p15), in a patient with AML (M2) accompanied by non-Hodgkin lymphoma and gastric cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fusion of the nucleoporin gene, NUP98, and the putative RNA helicase gene, DDX10, by inversion 11 (p15q22) chromosome translocation in a patient with etoposide-related myelodysplastic syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lens epithelium-derived growth factor (LEDGF/p75) and p52 are derived from a single gene by alternative splicing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
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7 January 2021
based on heuristic
inferred from DOI database lookup
t(4;11)(q21;p15) translocation involving NUP98 and RAP1GDS1 genes: characterization of a new subset of T acute lymphoblastic leukaemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human CAN protein, a putative oncogene product associated with myeloid leukemogenesis, is a nuclear pore complex protein that faces the cytoplasm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of 11p15 and 3q21q26 in therapy-related myeloid leukemia (t-ML) in children. Case reports and review of the literature
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion and duplication sequences induced in CHO cells by teniposide (VM-26), a topoisomerase II targeting drug, can be explained by the processing of DNA nicks produced by the drug-topoisomerase interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2402269
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.LEU.2402269
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11681408
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681408%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
Dimensions Publication ID
1023217175
0 references
PubMed publication ID
11681408
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11681408
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681408%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 December 2019
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