(Q34430268)

2 August 2017

title

Low-dose paclitaxel synergizes with oncolytic adenoviruses via mitotic slippage and apoptosis in ovarian cancer (English)

1 reference

2 August 2017

1 reference

1 reference

1 reference

1 reference

6

I. A. McNeish

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20729921

20 June 2024

author name string

C. K. Ingemarsdotter

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20729921

20 June 2024

S. K. Baird

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20729921

20 June 2024

C. M. Connell

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20729921

20 June 2024

D. Öberg

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20729921

20 June 2024

G. Halldén

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20729921

20 June 2024

language of work or name

English

0 references

publication date

23 August 2010

1 reference

full work available at URL

2 August 2017

https://www.nature.com/articles/onc2010335.pdf

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20729921

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20729921/pdf/?tool=EBI

20 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20729921

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20729921/?tool=EBI

20 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20729921

https://europepmc.org/articles/PMC3007619

20 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20729921

https://europepmc.org/articles/PMC3007619?pdf=render

20 June 2024

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20729921

http://www.nature.com/articles/onc2010335.pdf

20 June 2024

https://api.crossref.org/works/10.1038/ONC.2010.335

1 reference

http://www.nature.com/articles/onc2010335

20 June 2024

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.335

20 June 2024

1 reference

2 August 2017

volume

29

1 reference

2 August 2017

issue

45

1 reference

2 August 2017

page(s)

6051-6063

1 reference

describes a project that uses

2 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3007619/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/onc.2010.335

0 references

cites work

p21 Promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker

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Mechanism of G1-like arrest by low concentrations of paclitaxel: next cell cycle p53-dependent arrest with sub G1 DNA content mediated by prolonged mitosis

6 July 2018

1 reference

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GEF-H1 couples nocodazole-induced microtubule disassembly to cell contractility via RhoA.

6 July 2018

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Survival of aneuploid, micronucleated and/or polyploid cells: crosstalk between ploidy control and apoptosis

6 July 2018

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Oncolytic adenoviral mutants induce a novel mode of programmed cell death in ovarian cancer

6 July 2018

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E1A-expressing adenoviral E3B mutants act synergistically with chemotherapeutics in immunocompetent tumor models

6 July 2018

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Intracellular trafficking of adenovirus: many means to many ends

6 July 2018

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Quantifying the activity of adenoviral E1A CR2 deletion mutants using renilla luciferase bioluminescence and 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography imaging.

6 July 2018

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E1B55K-deleted adenovirus (ONYX-015) overrides G1/S and G2/M checkpoints and causes mitotic catastrophe and endoreduplication in p53-proficient normal cells

6 July 2018

1 reference

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Retinoblastoma family proteins as key targets of the small DNA virus oncoproteins.

6 July 2018

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Drug insight: cancer therapy strategies based on restoration of endogenous cell death mechanisms

6 July 2018

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Infection with replication-deficient adenovirus induces changes in the dynamic instability of host cell microtubules

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3007619

Mitosis: a matter of getting rid of the right protein at the right time

6 July 2018

1 reference

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CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex

6 July 2018

1 reference

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Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.

6 July 2018

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Fluorescently labeled adenovirus with pIX-EGFP for vector detection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3007619

Post-translational modifications regulate microtubule function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3007619

Adenovirus ADP protein (E3-11.6K), which is required for efficient cell lysis and virus release, interacts with human MAD2B

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3007619

E1A deregulates the centrosome cycle in a Ran GTPase-dependent manner.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3007619

The RB and p53 pathways in cancer

6 July 2018

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Differential mitotic responses to microtubule-stabilizing and -destabilizing drugs

6 July 2018

1 reference

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Adenovirus E4orf4 protein induces PP2A-dependent growth arrest in Saccharomyces cerevisiae and interacts with the anaphase-promoting complex/cyclosome

6 July 2018

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Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts

6 July 2018

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Induction of apoptosis by adenovirus E4orf4 protein is specific to transformed cells and requires an interaction with protein phosphatase 2A.

6 July 2018

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The adenovirus death protein (E3-11.6K) is required at very late stages of infection for efficient cell lysis and release of adenovirus from infected cells

6 July 2018

1 reference

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6 July 2018

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Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer

6 July 2018

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Processing of vimentin occurs during the early stages of adenovirus infection

6 July 2018

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6 July 2018

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6 July 2018

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Paclitaxel and vincristine potentiate adenoviral oncolysis that is associated with cell cycle and apoptosis modulation, whereas they differentially affect the viral life cycle in non-small-cell lung cancer cells.

6 July 2018

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Nuclear survivin abrogates multiple cell cycle checkpoints and enhances viral oncolysis.

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.335

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21 January 2018

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The adenovirus E4orf4 protein induces growth arrest and mitotic catastrophe in H1299 human lung carcinoma cells

21 January 2018

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Activity of the adenoviral E1A deletion mutant dl922-947 in ovarian cancer: comparison with E1A wild-type viruses, bioluminescence monitoring, and intraperitoneal delivery in icodextrin.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.335

Phase II trial of weekly single-agent paclitaxel in platinum/paclitaxel-refractory ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.335

Use of adenovirus protein IX (pIX) to display large polypeptides on the virion--generation of fluorescent virus through the incorporation of pIX-GFP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.335

Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycle

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.335

A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3007619

Combinations of paclitaxel and vinblastine and their effects on tubulin polymerization and cellular cytotoxicity: characterization of a synergistic schedule

27 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.335

Dose-dense paclitaxel once a week in combination with carboplatin every 3 weeks for advanced ovarian cancer: a phase 3, open-label, randomised controlled trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.335

Altered cell cycle progression and aberrant mitosis in adenovirus-infected rodent cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.335

An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20729921

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pulse treatment of interphasic HeLa cells with nanomolar doses of docetaxel affects centrosome organization and leads to catastrophic exit of mitosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20729921

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2010.335

1 reference

Dimensions Publication ID

2 August 2017

0 references

1 reference

2 August 2017

1 reference