(Q34431070)

2 August 2017

title

Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity (English)

1 reference

2 August 2017

main subject

Caenorhabditis elegans

0 references

neurotoxicity

1 reference

Putative RNA exonuclease pqe-1 CELE_F52C9.8

inferred from title

1 reference

GOA release 2020-03-11

1 reference

Peter W Faber

1

1 reference

2 August 2017

Cindy Voisine

2

1 reference

2 August 2017

Daphne C King

3

1 reference

2 August 2017

Emily A Bates

4

1 reference

2 August 2017

Anne C Hart

5

1 reference

2 August 2017

language of work or name

English

0 references

publication date

16 December 2002

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

published in

1 reference

2 August 2017

volume

99

1 reference

2 August 2017

issue

26

1 reference

2 August 2017

page(s)

17131-17136

1 reference

The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans

2 August 2017

cites work

1 reference

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Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

6 July 2018

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A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila

6 July 2018

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Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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CREB-binding protein sequestration by expanded polyglutamine

6 July 2018

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Transcriptional dysregulation in Huntington's disease

6 July 2018

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6 July 2018

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Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans

6 July 2018

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Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast

6 July 2018

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Genetic suppression of polyglutamine toxicity in Drosophila

6 July 2018

1 reference

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Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila

6 July 2018

1 reference

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Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

6 July 2018

1 reference

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Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone

6 July 2018

1 reference

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Glutamine repeats and neurodegenerative diseases: molecular aspects

6 July 2018

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Distinct signaling pathways mediate touch and osmosensory responses in a polymodal sensory neuron.

6 July 2018

1 reference

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Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation

6 July 2018

1 reference

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Genome sequence of the nematode C. elegans: a platform for investigating biology

6 July 2018

1 reference

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Huntingtin interacts with a family of WW domain proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

The genetic defect causing Huntington's disease: repeated in other contexts?

6 July 2018

1 reference

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Genotypes at the GluR6 kainate receptor locus are associated with variation in the age of onset of Huntington disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

Glutamine repeats and inherited neurodegenerative diseases: molecular aspects

6 July 2018

1 reference

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Transposon Tc1-derived, sequence-tagged sites in Caenorhabditis elegans as markers for gene mapping

6 July 2018

1 reference

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Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

A dual mechanosensory and chemosensory neuron in Caenorhabditis elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

Neuropathological classification of Huntington's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

Huntington's disease. Pathogenesis and management

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

Mutant sensory cilia in the nematode Caenorhabditis elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

The Caenorhabditis elegans rol-6 gene, which interacts with the sqt-1 collagen gene to determine organismal morphology, encodes a collagen

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

Evidence for the GluR6 gene associated with younger onset age of Huntington's disease

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.262544899

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.262544899

Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.262544899

Identification of genes that modify ataxin-1-induced neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.262544899

Phagocytosis promotes programmed cell death in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.262544899

Genomic analysis of gene expression in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.262544899

Caenorhabditis elegans rab-3 mutant synapses exhibit impaired function and are partially depleted of vesicles.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139281

Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease

27 October 2018

1 reference

12 December 2020

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

1 reference

12 December 2020

Regulation of Caenorhabditis elegans degenerin proteins by a putative extracellular domain

1 reference

12 December 2020

Lethal mutations defining 112 complementation groups in a 4.5 Mb sequenced region of Caenorhabditis elegans chromosome III

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.262544899

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference