(Q34433733)

2 August 2017

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title

A review and rationale for the use of genetically engineered animals in the study of traumatic brain injury (English)

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2 August 2017

main subject

traumatic brain injury

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8

Trojanowski JQ

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2 August 2017

Longhi L

1

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2 August 2017

Saatman KE

2

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2 August 2017

Raghupathi R

3

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2 August 2017

Laurer HL

4

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2 August 2017

Lenzlinger PM

5

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2 August 2017

Riess P

6

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2 August 2017

Neugebauer E

7

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2 August 2017

Lee VM

9

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2 August 2017

Grady MS

10

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2 August 2017

Graham DI

11

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2 August 2017

McIntosh TK

12

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2 August 2017

publication date

1 November 2001

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Journal of Cerebral Blood Flow & Metabolism

2 August 2017

published in

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2 August 2017

volume

21

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2 August 2017

issue

11

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2 August 2017

page(s)

1241-1258

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https://scigraph.springernature.com/pub.10.1097/00004647-200111000-00001

2 August 2017

exact match

0 references

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21 January 2018

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Transgenic mice and knockout mutants in the study of oxidative stress in brain injury

21 January 2018

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Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury.

21 January 2018

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Apoptotic morphology of dentate gyrus granule cells following experimental cortical impact injury in rats: possible role in spatial memory deficits

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21 January 2018

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21 January 2018

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

21 January 2018

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Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice

21 January 2018

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Evidence for normal aging of the septo-hippocampal cholinergic system in apoE (-/-) mice but impaired clearance of axonal degeneration products following injury

21 January 2018

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Experimental brain injury induces differential expression of tumor necrosis factor-alpha mRNA in the CNS.

21 January 2018

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Behavioral responses of C57BL/6, FVB/N, and 129/SvEMS mouse strains to traumatic brain injury: implications for gene targeting approaches to neurotrauma

21 January 2018

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Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury

21 January 2018

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

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Expression of insulin-like growth factor I by astrocytes in response to injury.

21 January 2018

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Localization of insulin-like growth factor I (IGF-I)-like immunoreactivity in the developing and adult rat brain

21 January 2018

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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

21 January 2018

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Tau hyperphosphorylation in apolipoprotein E-deficient and control mice after closed head injury.

21 January 2018

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https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

21 January 2018

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Recent advances in neurotrauma

21 January 2018

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Bcl-2 family gene products in cerebral ischemia and traumatic brain injury

21 January 2018

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https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Experimental axonal injury triggers interleukin-6 mRNA, protein synthesis and release into cerebrospinal fluid

21 January 2018

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https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

The biochemistry of apoptosis

21 January 2018

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Intracerebral inflammatory response to experimental brain contusion.

21 January 2018

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Nitric oxide, the enigmatic neuronal messenger: its role in synaptic plasticity.

21 January 2018

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

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Apoptosis and expression of p53 response proteins and cyclin D1 after cortical impact in rat brain.

21 January 2018

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Bax-deficient mice with lymphoid hyperplasia and male germ cell death

21 January 2018

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Impaired immune and acute-phase responses in interleukin-6-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Interleukin-6 released in human cerebrospinal fluid following traumatic brain injury may trigger nerve growth factor production in astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Temporal patterns of poly(ADP-ribose) polymerase activation in the cortex following experimental brain injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Pharmacologic inhibition of poly(ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Experimental models of brain trauma

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Neurodegenerative tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

21 January 2018

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The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

21 January 2018

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https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

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21 January 2018

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21 January 2018

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Attenuation of acute and chronic damage following traumatic brain injury in copper, zinc-superoxide dismutase transgenic mice.

21 January 2018

1 reference

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

1 reference

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Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Cold injury in mice: a model to study mechanisms of brain edema and neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Overexpression of Bcl-2 is neuroprotective after experimental brain injury in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Increased vulnerability of NFH-LacZ transgenic mouse to traumatic brain injury-induced behavioral deficits and cortical damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Temporal profile of apoptotic-like changes in neurons and astrocytes following controlled cortical impact injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Impaired brain development and reduced astrocyte response to injury in transgenic mice expressing IGF binding protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Rehabilitation of Persons With Traumatic Brain Injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Expression of the human beta-amyloid precursor protein gene from a yeast artificial chromosome in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Disruption of the blood-brain interface in neonatal rat neocortex induces a transient expression of metallothionein in reactive astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Workshop on animal models of traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

BCL-2 overexpression attenuates cortical cell loss after traumatic brain injury in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Apoptosis after traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Growth retardation and hyperglycemia in insulin-like growth factor binding protein-1 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Multiple molecular penumbras after focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

The mapping of transgenes by fluorescence in situ hybridization on G-banded mouse chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Closed head injury triggers early production of TNF alpha and IL-6 by brain tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Inhibition of tumor necrosis factor alpha (TNFalpha) activity in rat brain is associated with cerebroprotection after closed head injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Oxidative stress in closed-head injury: brain antioxidant capacity as an indicator of functional outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Dual role of tumor necrosis factor alpha in brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Brain trauma induces massive hippocampal neuron death linked to a surge in beta-amyloid levels in mice overexpressing mutant amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Genetic influences on cellular reactions to CNS injury: the reactive response of astrocytes in denervated neuropil regions in mice carrying a mutation (Wld(S)) that causes delayed Wallerian degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Genetic approaches to neurotrauma research: opportunities and potential pitfalls of murine models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Association of apolipoprotein E polymorphism with outcome after head injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Re-examination of ex-boxers' brains using immunohistochemistry with antibodies to amyloid ?-protein and tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Parkinson's disease and related neurodegenerative synucleinopathies linked to progressive accumulations of synuclein aggregates in brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

The effect of brain temperature on acute inflammation after traumatic brain injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Soluble adhesion molecules in CSF are increased in children with severe head injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Effect of traumatic brain injury in mice deficient in intercellular adhesion molecule-1: assessment of histopathologic and functional outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Reduction of cognitive and motor deficits after traumatic brain injury in mice deficient in poly(ADP-ribose) polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Effects of pegorgotein on neurologic outcome of patients with severe head injury. A multicenter, randomized controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Apoptosis in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Regional and temporal alterations in DNA fragmentation factor (DFF)-like proteins following experimental brain trauma in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Induction of apoptosis in mature T cells by tumour necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

Increases in bcl-2 protein in cerebrospinal fluid and evidence for programmed cell death in infants and children after severe traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200111000-00001

10.1097/00004647-200111000-00001

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

2 August 2017

1049335183

0 references

1 reference