(Q48357472)

10 February 2018

review article

1 reference

title

Transgenic mouse models of Alzheimer's disease and amyotrophic lateral sclerosis. (English)

1 reference

10 February 2018

amyotrophic lateral sclerosis

main subject

Alzheimer's disease

0 references

0 references

author name string

Borchelt DR

1

1 reference

10 February 2018

Wong PC

2

1 reference

10 February 2018

Sisodia SS

3

1 reference

10 February 2018

Price DL

4

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10 February 2018

publication date

1 October 1998

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10 February 2018

published in

Brain Pathology

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10 February 2018

volume

8

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10 February 2018

issue

4

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10 February 2018

page(s)

735-757

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10 February 2018

Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Cognitive and neurobiologic markers of early Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Choline acetyltransferase immunoreactivity in neuritic plaques of Alzheimer brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Incidence of dementia and probable Alzheimer's disease in a general population: the Framingham Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Role of excitotoxicity in human neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Reduced numbers of somatostatin receptors in the cerebral cortex in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Loss of neurons of origin of the adrenergic projection to cerebral cortex (nucleus locus ceruleus) in senile dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Choline acetyltransferase activity and histopathology of frontal neocortex from biopsies of demented patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Alzheimer's disease affects limbic nuclei of the thalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Neuropathological stageing of Alzheimer-related changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Age, neurofibrillary changes, A beta-amyloid and the onset of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Pattern of brain destruction in Parkinson's and Alzheimer's diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

The central nervous system in motor neurone disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Expression of APP in brains of transgenic mice containing the entire human APP gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Mutations of the presenilin I gene in families with early-onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Proximal axonal enlargement in motor neuron disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Aminergic systems in Alzheimer's disease and Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Reciprocal changes in corticotropin-releasing factor (CRF)-like immunoreactivity and CRF receptors in cerebral cortex of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Cortical biopsy in Alzheimer's disease: diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations. Intraventricular Bethanecol Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Aging and the brain: a new frontier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Dyslexia: automated diagnosis by computerized classification of brain electrical activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Inflammatory mechanisms in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Cleavage of amyloid beta peptide during constitutive processing of its precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Neuropeptides in Alzheimer type dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Neurochemical studies of early-onset Alzheimer's disease. Possible influence on treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Excitatory amino acids and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Synaptic loss in Alzheimer's disease and other dementias

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Region-specific loss of glutamate innervation in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Natural history of amyotrophic lateral sclerosis in a database population. Validation of a scoring system and a model for survival prediction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Regional localization of human extracellular superoxide dismutase gene to 4pter-q21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Transgenic mouse brain histopathology resembles early Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Familial amyotrophic lateral sclerosis. A subgroup characterized by posterior and spinocerebellar tract involvement and hyaline inclusions in the anterior horn cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Alzheimer's disease: cell-specific pathology isolates the hippocampal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Perforant pathway changes and the memory impairment of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Complement mRNA in the mammalian brain: responses to Alzheimer's disease and experimental brain lesioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Lewy body-like hyaline inclusions in sporadic motor neuron disease are ubiquitinated

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Sporadic lower motor neuron disease with Lewy body-like inclusions: a new subgroup?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

The aging brain. Limitations in our knowledge and future approaches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Development of dementing illnesses in an 80-year-old volunteer cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Differential expression of amyloid precursor protein mRNAs in cases of Alzheimer's disease and in aged nonhuman primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Epitopes that span the tau molecule are shared with paired helical filaments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Glutamate-, glutaminase-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Altered metabolism of familial Alzheimer's disease-linked amyloid precursor protein variants in yeast artificial chromosome transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Neurofilament function and dysfunction: involvement in axonal growth and neuronal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Disruption of the cytoskeleton in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Regional heterogeneity of choline acetyltransferase activity in primate neocortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Evidence for a six-transmembrane domain structure of presenilin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

A familial Alzheimer's disease locus on chromosome 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Identification and expression analysis of a potential familial Alzheimer disease gene on chromosome 1 related to AD3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

New pathological findings in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Ubiquitin in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Tau as a marker for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

The progression of the pathological changes of Alzheimer's disease in frontal and temporal neocortex examined both at biopsy and at autopsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Immunoelectron microscopic study of synaptic pathology in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Quantitative immunohistochemistry of synaptophysin in human neocortex: an alternative method to estimate density of presynaptic terminals in paraffin sections

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Amyloid plaque core protein in Alzheimer disease and Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Basophilic inclusions in sporadic juvenile amyotrophic lateral sclerosis: an immunocytochemical and ultrastructural study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Acetylcholinesterase-rich pyramidal neurons in the human neocortex and hippocampus: absence at birth, development during the life span, and dissolution in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Butyrylcholinesterase reactivity differentiates the amyloid plaques of aging from those of dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Cholinesterases in the amyloid angiopathy of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Neuropathologic assessment of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Cerebral amyloid deposition and diffuse plaques in "normal" aging: Evidence for presymptomatic and very mild Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Life and death of neurons in the aging brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Accumulation of phosphorylated neurofilaments in anterior horn motoneurons of amyotrophic lateral sclerosis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Mis-sense mutation Val&rarr;Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Brain transplants of cells expressing the carboxyl-terminal fragment of the Alzheimer amyloid protein precursor cause specific neuropathology in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

The endosomal-lysosomal system of neurons: new roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

The beta-amyloid protein precursor of Alzheimer disease has soluble derivatives found in human brain and cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Soluble derivatives of the beta amyloid protein precursor of Alzheimer's disease are labeled by antisera to the beta amyloid protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Persistence of cholinergic neurons in the basal nucleus in a brain with senile dementia of the Alzheimer's type demonstrated by immunohistochemical staining for choline acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Convergent cholinergic activities in aging and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Extensive loss of choline acetyltransferase activity is not reflected by neuronal loss in the nucleus of Meynert in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Toxicity of synthetic A beta peptides and modeling of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Cellular and molecular biology of Alzheimer's disease and animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Endoproteolytic processing and stabilization of wild-type and mutant presenilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Deletions in the survival motor neuron gene on 5q13 in autosomal recessive spinal muscular atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of Alzheimer type

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Correlation between scores for dementia and counts of 'senile plaques' in cerebral grey matter of elderly subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Human aging: usual and successful

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Amyotrophic lateral sclerosis: human challenge for neuroscience

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Synapse loss in the temporal lobe in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Amygdala cell loss and atrophy in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Skeletal and CNS defects in Presenilin-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Beta-amyloid precursor protein cleavage by a membrane-bound protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

The genetic defect causing familial Alzheimer's disease maps on chromosome 21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Protein oxidation and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Basal forebrain neurons provide major cholinergic innervation of primate neocortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Amyotrophic lateral sclerosis: Part 1. Clinical features, pathology, and ethical issues in management.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Observations on the brains of non-demented old people

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Observations on the brains of demented old people

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Cell loss in the locus coeruleus in senile dementia of Alzheimer type.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

In situ labeling of dying cortical neurons in normal aging and in Alzheimer's disease: correlations with senile plaques and disease progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Cell loss and shrinkage in the nucleus basalis Meynert complex in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Familial Alzheimer's chromosome 14 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Nicotinic acetylcholine binding sites in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Astroglial overproduction of TGF-beta 1 enhances inflammatory central nervous system disease in transgenic mice .

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Mechanisms of neuronal degeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

The neuropathology of aminergic nuclei in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Presenilin Proteins Undergo Heterogeneous Endoproteolysis between Thr291and Ala299and Occur as Stable N- and C-Terminal Fragments in Normal and Alzheimer Brain Tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Analysis of the functional effects of a mutation in SOD1 associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Heparan sulfate-like immunoreactivity in the spinal cord in motor neuron disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

Toxic mutants in Charcot's sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00198.X

10.1111/J.1750-3639.1998.TB00198.X

21 January 2018

Identifiers

DOI

1 reference

10 February 2018

PubMed ID

9804381

1 reference

10 February 2018