(Q34446012)

2 August 2017

1 reference

title

Gene therapy against neurological insults: sparing neurons versus sparing function (English)

1 reference

2 August 2017

0 references

Dumas TC

1

1 reference

PubMed ID

11718873

2 August 2017

Sapolsky RM

series ordinal

2

1 reference

2 August 2017

1 December 2001

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2 August 2017

Trends in Neurosciences

1 reference

2 August 2017

24

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2 August 2017

695-700

1 reference

2 August 2017

12

1 reference

Calcium: still center-stage in hypoxic-ischemic neuronal death

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Etiology and pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Corticospinal tract regrowth

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Energetics in the pathogenesis of neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Gene therapy using viral vectors for acute neurologic insults

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Gene therapies that enhance hippocampal neuron survival after an excitotoxic insult are not equivalent in their ability to maintain synaptic transmission

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

An adenoviral vector expressing the glucose transporter protects cultured striatal neurons from 3-nitropropionic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Sparing of neuronal function postseizure with gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Genetically modified fibroblasts producing NGF protect hippocampal neurons after ischemia in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Inhibition of caspases prevents cell death of hippocampal CA1 neurons, but not impairment of hippocampal long-term potentiation following global ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Caspase-3 mediated neuronal death after traumatic brain injury in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Limitations in the neuroprotective potential of gene therapy with Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Neuroprotection with herpes simplex vectors expressing virally derived anti-apoptotic agents.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Herpes simplex virus vectors overexpressing the glucose transporter gene protect against seizure-induced neuron loss

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Gene transfer of calbindin D28k cDNA via herpes simplex virus amplicon vector decreases cytoplasmic calcium ion response and enhances neuronal survival following glutamatergic challenge but not following cyanide

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Calbindin overexpression buffers hippocampal cultures from the energetic impairments caused by glutamate

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Viral gene delivery selectively restores feeding and prevents lethality of dopamine-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Herpes simplex virus vector-mediated expression of Bcl-2 prevents 6-hydroxydopamine-induced degeneration of neurons in the substantia nigra in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Herpes simplex virus vector-mediated expression of Bcl-2 protects spinal motor neurons from degeneration following root avulsion

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

DNA plasmid that codes for human Bcl-2 gene preserves axotomized Clarke's nucleus neurons and reduces atrophy after spinal cord hemisection in adult rats

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Intercostal nerve implants transduced with an adenoviral vector encoding neurotrophin-3 promote regrowth of injured rat corticospinal tract fibers and improve hindlimb function

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Partial functional recovery of paraplegic rat by adenovirus-mediated gene delivery of constitutively active MEK1.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Adenovirus-mediated expression of ciliary neurotrophic factor (CNTF) rescues axotomized rat retinal ganglion cells but does not support axonal regeneration in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Bcl-2 overexpression per se does not promote regeneration of neonatal crushed optic fibers

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Rescue from death but not from functional impairment: caspase inhibition protects dopaminergic cells against 6-hydroxydopamine-induced apoptosis but not against the loss of their terminals

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Selective reduction of hippocampal dentate frequency-potentiation in striatally lesioned rats with impaired place learning.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Memories of NMDA receptors and LTP.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Metaplasticity of mossy fiber synaptic transmission involves altered release probability

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Neuroprotection with Bcl-2(20-34) peptide against trauma.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Gene therapy effectiveness differs for neuronal survival and behavioral performance

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Multi-site partitioned delivery of human tyrosine hydroxylase gene with phenotypic recovery in Parkinsonian rats

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Delivery of a GDNF gene into the substantia nigra after a progressive 6-OHDA lesion maintains functional nigrostriatal connections

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Adenovirus-mediated transfer of the neurotrophin-3 gene into skeletal muscle of pmn mice: therapeutic effects and mechanisms of action

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

The mitochondrial death/life regulator in apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Neuroprotective potential of a viral vector system induced by a neurological insult

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901956-1

7 January 2021

10.1016/S0166-2236(00)01956-1

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

11718873