(Q34446281)

2 August 2017

title

Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia (English)

1 reference

2 August 2017

1 reference

18

Xiaole Shirley Liu

1 reference

2 August 2017

Chongzhi Zang

3

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Katherine S Forsyth

object named as

Katherine S Forsyth

10

0 references

Bradley Bernstein

16

object named as

Bradley E Bernstein

1 reference

2 August 2017

7

Birgit Knoechel

1 reference

2 August 2017

Yumi Yashiro-Ohtani

1

1 reference

2 August 2017

Hongfang Wang

2

1 reference

2 August 2017

Kelly L Arnett

4

1 reference

2 August 2017

Will Bailis

5

1 reference

2 August 2017

Yugong Ho

6

1 reference

2 August 2017

Claudia Lanauze

8

1 reference

2 August 2017

Lumena Louis

9

1 reference

2 August 2017

Sujun Chen

11

1 reference

2 August 2017

Yoonjie Chung

12

1 reference

2 August 2017

Jonathan Schug

13

1 reference

2 August 2017

Gerd A Blobel

14

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2 August 2017

Stephen A Liebhaber

15

1 reference

2 August 2017

Stephen C Blacklow

17

1 reference

2 August 2017

Jon C Aster

19

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2 August 2017

Warren S Pear

20

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2 August 2017

language of work or name

English

0 references

publication date

4 November 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

published in

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2 August 2017

volume

111

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2 August 2017

issue

46

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2 August 2017

page(s)

E4946-53

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An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Notch signaling at a glance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Selective inhibition of tumor oncogenes by disruption of super-enhancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Master transcription factors and mediator establish super-enhancers at key cell identity genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Whole-genome sequencing identifies recurrent somatic NOTCH2 mutations in splenic marginal zone lymphoma.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Recent advances on NOTCH signaling in T-ALL.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Notch dimerization is required for leukemogenesis and T-cell development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

A beta-catenin/TCF-coordinated chromatin loop at MYC integrates 5' and 3' Wnt responsive enhancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Modulation of gamma-secretase specificity using small molecule allosteric inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

A clustering approach for identification of enriched domains from histone modification ChIP-Seq data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Model-based analysis of ChIP-Seq (MACS)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246292

SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes.

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1407079111

The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1407079111

The Tumor Suppressor Ikaros Shapes the Repertoire of Notch Target Genes in T Cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25369933

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1407079111

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference