(Q34448655)

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Nuclear orphan receptor TAK1/TR4-deficient mice are protected against obesity-linked inflammation, hepatic steatosis, and insulin resistance

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

Nuclear orphan receptor TAK1/TR4-deficient mice are protected against obesity-linked inflammation, hepatic steatosis, and insulin resistance (English)

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Europe PubMed Central

PubMed publication ID

2 August 2017

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1 reference

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insulin resistance

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Anton M. Jetten

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Anton M Jetten

11

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5

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Carl D Bortner

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Europe PubMed Central

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2 August 2017

author name string

Hong Soon Kang

1

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2 August 2017

Kyoko Okamoto

2

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2 August 2017

Yong-Sik Kim

3

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2 August 2017

Yukimasa Takeda

4

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2 August 2017

Huaixin Dang

6

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2 August 2017

Taira Wada

7

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2 August 2017

Wen Xie

8

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2 August 2017

Xiao-Ping Yang

9

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2 August 2017

Grace Liao

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2 August 2017

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23 September 2010

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2 August 2017

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2 August 2017

60

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2 August 2017

1

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Europe PubMed Central

PubMed publication ID

2 August 2017

177-188

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Europe PubMed Central

PubMed publication ID

2 August 2017

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

27 August 2021

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April 2022 Public Data File from Crossref

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Altered cerebellar development in nuclear receptor TAK1/ TR4 null mice is associated with deficits in GLAST(+) glia, alterations in social behavior, motor learning, startle reactivity, and microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Activation of testicular orphan receptor 4 by fatty acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Genome-wide mRNA expression analysis of hepatic adaptation to high-fat diets reveals switch from an inflammatory to steatotic transcriptional program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Normalization of obesity-associated insulin resistance through immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

CIDE proteins and metabolic disorders.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

SREBPs: physiology and pathophysiology of the SREBP family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

The nuclear orphan receptor COUP-TFII plays an essential role in adipogenesis, glucose homeostasis, and energy metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Hepatic triacylglycerol accumulation and insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Mechanisms of macrophage activation in obesity-induced insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

A functional interaction between RIP140 and PGC-1alpha regulates the expression of the lipid droplet protein CIDEA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Insulin sensitivity: modulation by nutrients and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Lipid droplets: FSP27 knockout enhances their sizzle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Cidea is associated with lipid droplets and insulin sensitivity in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Hepatic steatosis in leptin-deficient mice is promoted by the PPARgamma target gene Fsp27.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Fat-specific protein 27 regulates storage of triacylglycerol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Inflammation and metabolic disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Adipocytokines: mediators linking adipose tissue, inflammation and immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Deficits in motor coordination with aberrant cerebellar development in mice lacking testicular orphan nuclear receptor 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Growth retardation and abnormal maternal behavior in mice lacking testicular orphan nuclear receptor 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Nuclear receptor corepressor RIP140 regulates fat accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Obesity is associated with macrophage accumulation in adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Cidea-deficient mice have lean phenotype and are resistant to obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Prevalence and trends in overweight among US children and adolescents, 1999-2000

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Human and rat TR4 orphan receptors specify a subclass of the steroid receptor superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

TAK1: molecular cloning and characterization of a new member of the nuclear receptor superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Molecular cloning of new human TR2 receptors: a class of steroid receptor with multiple ligand-binding domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

6 July 2018

Activation of TR4 orphan nuclear receptor gene promoter by cAMP/PKA and C/EBP signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

27 October 2018

Loss of testicular orphan receptor 4 impairs normal myelination in mouse forebrain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

27 October 2018

Interleukin-1 receptor antagonist is upregulated during diet-induced obesity and regulates insulin sensitivity in rodents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012170

27 October 2018

Decreased fat mass in interleukin-1 receptor antagonist-deficient mice: impact on adipogenesis, food intake, and energy expenditure

1 reference

https://pubmed.ncbi.nlm.nih.gov/20864514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20864514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of TR4 Orphan Nuclear Receptor Reduces Phosphoenolpyruvate Carboxykinase Mediated Gluconeogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20864514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonalcoholic fatty liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20864514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB10-0628

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Europe PubMed Central

PubMed publication ID

2 August 2017

Internet Archive ID

pubmed-PMC3012170

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

ResearchGate publication ID

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