(Q34456971)

2 August 2017

1 reference

title

Cancer chemoprevention: scientific promise, clinical uncertainty (English)

1 reference

2 August 2017

Michael B Sporn

1

1 reference

PubMed ID

16205771

2 August 2017

Karen T Liby

series ordinal

2

1 reference

2 August 2017

1 October 2005

1 reference

Nature Clinical Practice Oncology

2 August 2017

1 reference

2 August 2017

2

1 reference

2 August 2017

10

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2 August 2017

518-525

1 reference

https://scigraph.springernature.com/pub.10.1038/ncponc0319

2 August 2017

0 references

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The history of cancer epigenetics

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Chemoprevention through the Keap1-Nrf2 signaling pathway by phase 2 enzyme inducers

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Nrf2 as a novel molecular target for chemoprevention

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Regulatory mechanisms controlling gene expression mediated by the antioxidant response element

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Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress

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Control of nitric oxide production by transforming growth factor-beta1: mechanistic insights and potential relevance to human disease.

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TGF-beta1 stimulates HO-1 via the p38 mitogen-activated protein kinase in A549 pulmonary epithelial cells

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Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

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Statins and the risk of colorectal cancer

21 January 2018

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Inflammation, atherosclerosis, and coronary artery disease

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Rosuvastatin upregulates the antioxidant defense protein heme oxygenase-1.

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Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection.

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Simvastatin attenuates expression of cytokine-inducible nitric-oxide synthase in embryonic cardiac myoblasts.

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Targeting the PI3K-Akt pathway in human cancer: rationale and promise

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Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions

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Transcription factors as targets for cancer therapy

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NF-kappaB functions as a tumour promoter in inflammation-associated cancer

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IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

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Roles and regulation of stat family transcription factors in human breast cancer

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The STATs of cancer--new molecular targets come of age

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Retinoid targeting of different D-type cyclins through distinct chemopreventive mechanisms

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The selective estrogen receptor modulator arzoxifene and the rexinoid LG100268 cooperate to promote transforming growth factor beta-dependent apoptosis in breast cancer

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Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein

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Inflammation in atherosclerosis

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Inflammatory processes in Alzheimer's disease

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Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2

21 January 2018

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Cancer: what should be done?

21 January 2018

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7 January 2021

Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study

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7 January 2021

Continuing outcomes relevant to Evista: breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene

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7 January 2021

Cancer statistics, 2005

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7 January 2021

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7 January 2021

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7 January 2021

Epigenetics and cancer

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7 January 2021

Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis

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7 January 2021

The biology and clinical relevance of the PTEN tumor suppressor pathway

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7 January 2021

Validating Stat3 in cancer therapy

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7 January 2021

Cyclin D1 as a target for chemoprevention

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7 January 2021

Mitochondria, Oxidative Damage, and Inflammation in Parkinson's Disease

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7 January 2021

Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1

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7 January 2021

Identifiers

DOI

10.1038/NCPONC0319

1 reference

PubMed ID

16205771

Dimensions Publication ID

2 August 2017

0 references

1 reference

PubMed ID

16205771