(Q34460797)

2 August 2017

title

PARP-1 modulation of mTOR signaling in response to a DNA alkylating agent (English)

1 reference

2 August 2017

Chantal Ethier

1

1 reference

2 August 2017

Maxime Tardif

series ordinal

2

1 reference

2 August 2017

Laura Arul

series ordinal

3

1 reference

2 August 2017

Guy G Poirier

series ordinal

4

1 reference

2 August 2017

language of work or name

English

0 references

publication date

24 October 2012

1 reference

2 August 2017

1 reference

2 August 2017

volume

7

1 reference

2 August 2017

issue

10

1 reference

2 August 2017

page(s)

e47978

1 reference

Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

24 October 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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6 July 2018

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AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cells

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mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling

6 July 2018

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6 July 2018

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Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1

6 July 2018

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Parthanatos, a messenger of death

6 July 2018

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The molecular "Jekyll and Hyde" duality of PARP1 in cell death and cell survival

6 July 2018

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LKB1 and AMP-activated protein kinase control of mTOR signalling and growth

6 July 2018

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TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells.

6 July 2018

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A complex interplay between Akt, TSC2 and the two mTOR complexes

6 July 2018

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PARP-1 is involved in autophagy induced by DNA damage.

6 July 2018

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Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

6 July 2018

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6 July 2018

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AMPK phosphorylation of raptor mediates a metabolic checkpoint

6 July 2018

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PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival

6 July 2018

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Regulation of macroautophagy by mTOR and Beclin 1 complexes

6 July 2018

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Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells

6 July 2018

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6 July 2018

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6 July 2018

Expanding mTOR signaling

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Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794.

6 July 2018

1 reference

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Autophagy and cell death.

6 July 2018

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Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

TOR signaling in growth and metabolism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation

6 July 2018

1 reference

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Pivotal role of Akt activation in mitochondrial protection and cell survival by poly(ADP-ribose)polymerase-1 inhibition in oxidative stress.

6 July 2018

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

6 July 2018

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6 July 2018

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The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

6 July 2018

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Alkylating DNA damage stimulates a regulated form of necrotic cell death

6 July 2018

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RAS and RHO GTPases in G1-phase cell-cycle regulation

6 July 2018

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Autophagy as a cell death and tumor suppressor mechanism

6 July 2018

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Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

AMP-activated protein kinase, super metabolic regulator

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

Role of AMP-activated protein kinase in mechanism of metformin action

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

Immunological determination and size characterization of poly(ADP-ribose) synthesized in vitro and in vivo.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

Methods for biochemical study of poly(ADP-ribose) metabolism in vitro and in vivo.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

Poly(ADP-ribose) in the cellular response to DNA damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480502

Poly(ADP-ribose) catabolism triggers AMP-dependent mitochondrial energy failure

6 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047978

Autophagy contributes to caspase-independent macrophage cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047978

Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047978

Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047978

Oxidative stress initiates DNA damager MNNG-induced poly(ADP-ribose)polymerase-1-dependent parthanatos cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047978

Poly (ADP-ribose) polymerase activity regulates apoptosis in HeLa cells after alkylating DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047978

MAPK, phosphatidylinositol 3-kinase, and mammalian target of rapamycin pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic signaling in CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047978

Measurements of ATP in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0047978

Structural and functional analysis of poly(ADP ribose) polymerase: an immunological study

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23110147

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Neither energy collapse nor transcription underlie in vitro neurotoxicity of poly(ADP-ribose) polymerase hyper-activation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23110147

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PARP-1-induced cell death through inhibition of the MEK/ERK pathway in MNNG-treated HeLa cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23110147

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0047978

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference