(Q34466530)

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Src-family kinases stabilize the neuromuscular synapse in vivo via protein interactions, phosphorylation, and cytoskeletal linkage of acetylcholine receptors.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16280586%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Src-family kinases stabilize the neuromuscular synapse in vivo via protein interactions, phosphorylation, and cytoskeletal linkage of acetylcholine receptors (English)

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Europe PubMed Central

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9 January 2020

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phosphorylation

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Christian Fuhrer

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9 January 2020

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Gayathri Sadasivam

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9 January 2020

Raffaella Willmann

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9 January 2020

Shuo Lin

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9 January 2020

Susanne Erb-Vögtli

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9 January 2020

Xian Chu Kong

5

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9 January 2020

Markus A Rüegg

6

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9 January 2020

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1 November 2005

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9 January 2020

Journal of Neuroscience

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9 January 2020

25

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9 January 2020

45

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9 January 2020

10479-10493

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9 January 2020

Phosphorylation and cytoskeletal anchoring of the acetylcholine receptor by Src class protein-tyrosine kinases. Activation by rapsyn

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of rapsyn and agrin in interaction of postsynaptic proteins with acetylcholine receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The intracellular domain of the nicotinic acetylcholine receptor alpha subunit mediates its coclustering with rapsyn

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The organization of the Golgi complex and microtubules in skeletal muscle is fiber type-dependent.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synapse elimination and indelible memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin--glycoprotein complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of rapsyn inhibits agrin-induced acetylcholine receptor clustering in muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agrin-induced acetylcholine receptor clustering is mediated by the small guanosine triphosphatases Rac and Cdc42

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dystrophin complex forms a mechanically strong link between the sarcolemma and costameric actin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dystroglycan complex is necessary for stabilization of acetylcholine receptor clusters at neuromuscular junctions and formation of the synaptic basement membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agrin-induced activation of acetylcholine receptor-bound Src family kinases requires Rapsyn and correlates with acetylcholine receptor clustering.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agrin-induced phosphorylation of the acetylcholine receptor regulates cytoskeletal anchoring and clustering

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src, Fyn, and Yes are not required for neuromuscular synapse formation but are necessary for stabilization of agrin-induced clusters of acetylcholine receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of the rapsyn RING-H2 domain with dystroglycan

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src-class kinases act within the agrin/MuSK pathway to regulate acetylcholine receptor phosphorylation, cytoskeletal anchoring, and clustering.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction, assembly, maturation and maintenance of a postsynaptic apparatus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholine receptors are required for agrin-induced clustering of postsynaptic proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C induces actin reorganization via a Src- and Rho-dependent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laminin-1 redistributes postsynaptic proteins and requires rapsyn, tyrosine phosphorylation, and Src and Fyn to stably cluster acetylcholine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuromuscular synaptogenesis: clustering of acetylcholine receptors revisited

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time course of skeletal muscle repair and gene expression following acute hind limb ischemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperative regulation by Rac and Rho of agrin-induced acetylcholine receptor clustering in muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapsyn-mediated clustering of acetylcholine receptor subunits requires the major cytoplasmic loop of the receptor subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New insights into the roles of agrin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of agrin-induced acetylcholine receptor aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of Src family kinases inhibits angiogenesis in vivo: implications for a mechanism involving organization of the actin cytoskeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling complexes for postsynaptic differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cortactin signalling and dynamic actin networks

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single pulse of agrin triggers a pathway that acts to cluster acetylcholine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased ratio of rapsyn to ACh receptor stabilizes postsynaptic receptors at the mouse neuromuscular synapse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphatase regulation of MuSK-dependent acetylcholine receptor clustering

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholine receptor clustering and triton solubility: Neural effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the postsynaptic 43-kDa protein from muscle cells that differ in acetylcholine receptor clustering activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mobility and detergent extractability of acetylcholine receptors on cultured rat myotubes: a correlation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of the neuromuscular junction: inductive interactions between cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural influence on the postnatal changes in acetylcholine receptor distribution at nerve-muscle junctions in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of the cytoskeletal framework with acetylcholine receptor on th surface of embryonic muscle cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific and redundant roles of Src and Fyn in organizing the cytoskeleton.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapsyn may function as a link between the acetylcholine receptor and the agrin-binding dystrophin-associated glycoprotein complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of the 43-kD protein disrupts acetylcholine receptor clustering in myotubes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation of α-tubulin is an early response to NGF and pp60v-src in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Utrophin actin binding domain: analysis of actin binding and cellular targeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assembly of the postsynaptic apparatus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the interaction of nicotinic acetylcholine receptors with the cytoskeleton by agrin-activated protein tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of two abundant protein tyrosine kinases in Torpedo electric organ that associate with the acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of the 43 kd postsynaptic protein with all subunits of the muscle nicotinic acetylcholine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agrin-induced acetylcholine receptor clustering in mammalian muscle requires tyrosine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional interaction of Src family kinases with the acetylcholine receptor in C2 myotubes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of muscle-specific kinase MuSK with the acetylcholine receptor in mammalian muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular functions regulated by Src family kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for in situ and in vitro association between beta-dystroglycan and the subsynaptic 43K rapsyn protein. Consequence for acetylcholine receptor clustering at the synapse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16280586

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.2103-05.2005

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16280586%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16280586%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16280586%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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