(Q34467710)

2 August 2017

1 reference

title

Conformational display: a role for switch polymorphism in the superfamily of regulatory GTPases (English)

1 reference

2 August 2017

S R Sprang

1

1 reference

2 August 2017

publication date

19 September 2000

1 reference

Science's STKE : signal transduction knowledge environment

2 August 2017

published in

1 reference

2 August 2017

volume

2000

1 reference

2 August 2017

issue

50

1 reference

2 August 2017

page(s)

pe1

1 reference

Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

G protein mechanisms: insights from structural analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Structural view of the Ran-Importin beta interaction at 2.3 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Conformational transitions in p21ras and in its complexes with the effector protein Raf-RBD and the GTPase activating protein GAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Helix unwinding in the effector region of elongation factor EF-Tu-GDP

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

An alpha to beta conformational switch in EF-Tu

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Regional polysterism in the GTP-bound form of the human c-Ha-Ras protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Structure of Gialpha1.GppNHp, autoinhibition in a galpha protein-substrate complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Crystal structure of active elongation factor Tu reveals major domain rearrangements

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Structure of Cdc42 bound to the GTPase binding domain of PAK

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Definition of the switch surface in the solution structure of Cdc42Hs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Structural Basis for Activation of ARF GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Conformational states of the nuclear GTP-binding protein Ran and its complexes with the exchange factor RCC1 and the effector protein RanBP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

An NMR comparison of the changes produced by different guanosine 5'-triphosphate analogs in wild-type and oncogenic mutant p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Conformational and dynamic differences between N-ras P21 bound to GTPgammaS and to GMPPNP as studied by NMR

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

Backbone dynamics of inactive, active, and effector-bound Cdc42Hs from measurements of (15)N relaxation parameters at multiple field strengths

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.50.PE1

21 January 2018

Identifiers

DOI

10.1126/STKE.2000.50.PE1

1 reference

2 August 2017

1 reference