(Q34468798)

2 August 2017

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title

Cell transformation by the middle T-antigen of polyoma virus (English)

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2 August 2017

Ichaso N

1

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2 August 2017

Dilworth SM

series ordinal

2

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2 August 2017

language of work or name

English

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publication date

1 November 2001

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2 August 2017

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2 August 2017

20

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2 August 2017

7908-7916

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2 August 2017

54

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204859

2 August 2017

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cites work

Mechanism of activation and function of protein kinase B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

The role of the Shc phosphotyrosine interaction/phosphotyrosine binding domain and tyrosine phosphorylation sites in polyoma middle T antigen-mediated cell transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Retinoic acid inhibits transformation by preventing phosphatidylinositol 3-kinase dependent activation of the c-fos promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

The carboxy terminus of pp60c-src is a regulatory domain and is involved in complex formation with the middle-T antigen of polyomavirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Characterization of pp85, a target of oncogenes and growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Tyrosine phosphorylation is a signal for the trafficking of pp85, an 85-kDa phosphorylated polypeptide associated with phosphatidylinositol kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Polyoma virus transforming protein associates with the product of the c-src cellular gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Functional asymmetry of the regions juxtaposed to the membrane-binding sequence of polyomavirus middle T antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Signal transduction in mammary tumorigenesis: a transgenic perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Polyoma virus middle T antigen: meddler or mimic?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Monoclonal antibodies against polyoma virus tumor antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Ras signalling and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Signalling by Src family kinases: lessons learnt from DNA tumour viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Regulation of cytoskeletal association by a basic amino acid motif in polyoma virus middle T antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Src family protein tyrosine kinases and cellular signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Association between src-kinases and the polyoma virus oncogene middle T-antigen requires PP2A and a specific sequence motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

A filterable agent, recovered from Ak leukemic extracts, causing salivary gland carcinomas in C3H mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Chaperones in cell cycle regulation and mitogenic signal transduction: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Akt signaling: linking membrane events to life and death decisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Polyomavirus middle T antigen as a probe for T cell antigen receptor-coupled signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Src tyrosine kinase is a novel direct effector of G proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Regulation of protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Protein kinase B/Akt is activated by polyomavirus middle-T antigen via a phosphatidylinositol 3-kinase-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

DNA tumor viruses and Src family tyrosine kinases, an intimate relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Regulation by tumour antigens defines a role for PP2A in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Association of polyomavirus middle tumor antigen with 14-3-3 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

The roles of individual polyoma virus early proteins in oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Expression of the large T protein of polyoma virus promotes the establishment in culture of "normal" rodent fibroblast cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Identification of binding sites on the regulatory A subunit of protein phosphatase 2A for the catalytic C subunit and for tumor antigens of simian virus 40 and polyomavirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Association of Polyomavirus middle tumor antigen with phospholipase C-gamma 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Polyoma middle T antigen activates the Ser/Thr kinase Akt in a PI3-kinase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Phosphorylation of middle T by pp60c-src: a switch for binding of phosphatidylinositol 3-kinase and optimal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Construction and Expression of a Recombinant DNA Gene Encoding a Polyomavirus Middle-Size Tumor Antigen with the Carboxyl Terminus of the Vesicular Stomatitis Virus Glycoprotein G

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

A role for the small GTPase Rac in polyomavirus middle-T antigen-mediated activation of the serum response element and in cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Phosphoinositide 3-kinases: a conserved family of signal transducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Association of protein phosphatase 2A with polyoma virus medium tumor antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Three-dimensional structure of the tyrosine kinase c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Detection of phosphotyrosine-containing proteins in polyomavirus middle tumor antigen-transformed cells after treatment with a phosphotyrosine phosphatase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

At the onset of transformation polyomavirus middle-T recruits shc and src to a perinuclear compartment coincident with condensation of endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

Association of the polyomavirus middle-T antigen with c-yes protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

pp60c-src binding to polyomavirus middle T-antigen (MT) requires residues 185 to 210 of the MT sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Peptide antibodies to the human c-fyn gene product demonstrate pp59c-fyn is capable of complex formation with the middle-T antigen of polyomavirus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Identification and characterization of the hamster polyomavirus middle T antigen.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

An 81 kd protein complexed with middle T antigen and pp60c-src: a possible phosphatidylinositol kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Serine 257 phosphorylation regulates association of polyomavirus middle T antigen with 14-3-3 proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Novel monoclonal antibodies that differentiate between the binding of pp60c-src or protein phosphatase 2A by polyomavirus middle T antigen.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Polyomavirus middle-T antigen associates with the kinase domain of Src-related tyrosine kinases.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Cytopathogenicity in tissue culture by a tumor virus from mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Oncogenic properties of the middle T antigens of polyomaviruses.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Characterization of polyoma mutants with altered middle and large T-antigens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Site-directed mutagenesis of polyomavirus middle-T antigen sequences encoding tyrosine 315 and tyrosine 250.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Mutants of polyomavirus middle-T antigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Catalytically inactive protein phosphatase 2A can bind to polyomavirus middle tumor antigen and support complex formation with pp60(c-src).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

The cellular proteins which can associate specifically with polyomavirus middle T antigen in human 293 cells include the major human 70-kilodalton heat shock proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Polyoma middle T antigen in HL-60 cells accelerates hematopoietic myeloid and monocytic cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Interactions of polyomavirus middle T with the SH2 domains of the pp85 subunit of phosphatidylinositol-3-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204859

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204859

1 reference

Dimensions Publication ID

2 August 2017

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1 reference