(Q34472013)

2 August 2017

title

A heat-shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair (English)

1 reference

Heat shock protein 90, alpha (cytosolic), class B member 1

2 August 2017

1 reference

1 reference

GOA release 2020-03-11

author

Sreenivasan Ponnambalam

12

Sreenivasan Ponnambalam

0 references

Stephen Wheatcroft

9

Stephen B Wheatcroft

1 reference

2 August 2017

10

Mark T Kearney

1 reference

2 August 2017

Nadira Yuldasheva

2

0 references

Caroline Pellet-Many

Caroline Pellet-Many

5

0 references

Antony M Latham

3

Antony M Latham

1 reference

2 August 2017

11

Ian C Zachary

1 reference

2 August 2017

Alexander F Bruns

1

1 reference

2 August 2017

Leyuan Bao

4

1 reference

2 August 2017

Paul Frankel

6

1 reference

2 August 2017

Sam L Stephen

7

1 reference

2 August 2017

Gareth J Howell

8

1 reference

2 August 2017

language of work or name

English

0 references

publication date

6 November 2012

1 reference

2 August 2017

1 reference

2 August 2017

volume

7

1 reference

2 August 2017

issue

11

1 reference

2 August 2017

page(s)

e48539

1 reference

Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

6 November 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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6 July 2018

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Proposal for a role of the Hsp90/Hsp70-based chaperone machinery in making triage decisions when proteins undergo oxidative and toxic damage

6 July 2018

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6 July 2018

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Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis.

6 July 2018

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Class II histone deacetylases play pivotal roles in heat shock protein 90-mediated proteasomal degradation of vascular endothelial growth factor receptors

6 July 2018

1 reference

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Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces or

6 July 2018

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6 July 2018

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6 July 2018

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A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCgamma1 activation and angiogenesis

6 July 2018

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Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo

6 July 2018

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6 July 2018

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Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2-mediated phosphorylation of FAK on Tyr407 in response to vascular endothelial growth factor

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

1 reference

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Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

6 July 2018

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Antiangiogenic properties of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin: an orally bioavailable heat shock protein 90 modulator

6 July 2018

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6 July 2018

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6 July 2018

Heat shock protein 90.

1 reference

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Integrin alphavbeta3, requirement for VEGFR2-mediated activation of SAPK2/p38 and for Hsp90-dependent phosphorylation of focal adhesion kinase in endothelial cells activated by VEGF

6 July 2018

1 reference

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ErbB2 degradation mediated by the co-chaperone protein CHIP

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491040

Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu

6 July 2018

1 reference

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Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release

6 July 2018

1 reference

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Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinase

6 July 2018

1 reference

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Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery

6 July 2018

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Dynamic activation of endothelial nitric oxide synthase by Hsp90.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491040

Intrinsic tyrosine kinase activity is required for vascular endothelial growth factor receptor 2 ubiquitination, sorting and degradation in endothelial cells.

6 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048539

Endothelial cell confluence regulates Weibel-Palade body formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048539

Activation of cytosolic phospholipase A2-{alpha} as a novel mechanism regulating endothelial cell cycle progression and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048539

Vascular endothelial growth factor-dependent down-regulation of Flk-1/KDR involves Cbl-mediated ubiquitination. Consequences on nitric oxide production from endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048539

Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048539

Dominant-negative Hsp90 reduces VEGF-stimulated nitric oxide release and migration in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048539

Chaperone-dependent regulation of endothelial nitric-oxide synthase intracellular trafficking by the co-chaperone/ubiquitin ligase CHIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048539

Geldanamycin enhances hepatocyte growth factor stimulation of eNOS phosphorylation in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048539

Heat shock cognate protein 70 is essential for Akt signaling in endothelial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048539

Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3491040

VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment

27 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048539

HSP90 and Akt modulate Ang-1-induced angiogenesis via NO in coronary artery endothelium

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23139789

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23139789

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Signal transduction by vascular endothelial growth factor receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23139789

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0048539

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference