(Q34473537)

2 August 2017

Selective elimination of mitochondrial mutations in the germline by genome editing (English)

1 reference

Juan Carlos Izpisúa Belmonte

2 August 2017

25

Juan Carlos Izpisua Belmonte

1 reference

2 August 2017

Pradeep Reddy

1

0 references

Jun Wu

Jun Wu

10

0 references

Nuria Montserrat

Nuria Montserrat

13

0 references

Francesc Cardellach

19

Francesc Cardellach

1 reference

2 August 2017

Ignacio Sancho-Martinez

16

Ignacio Sancho-Martinez

1 reference

2 August 2017

9

Yuji Tsunekawa

1 reference

2 August 2017

15

Guang-Hui Liu

1 reference

2 August 2017

8

Daiji Okamura

1 reference

2 August 2017

Alejandro Ocampo

2

1 reference

2 August 2017

Keiichiro Suzuki

3

1 reference

2 August 2017

Jinping Luo

4

1 reference

2 August 2017

Sandra R Bacman

5

1 reference

2 August 2017

Sion L Williams

6

1 reference

2 August 2017

Atsushi Sugawara

7

1 reference

2 August 2017

David Lam

11

1 reference

2 August 2017

Xiong Xiong

12

1 reference

2 August 2017

Concepcion Rodriguez Esteban

14

1 reference

2 August 2017

Dolors Manau

17

1 reference

2 August 2017

Salva Civico

18

1 reference

2 August 2017

Maria Del Mar O'Callaghan

20

1 reference

2 August 2017

Jaime Campistol

21

1 reference

2 August 2017

Huimin Zhao

22

1 reference

2 August 2017

Josep M Campistol

23

1 reference

2 August 2017

Carlos T Moraes

24

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 April 2015

1 reference

2 August 2017

11

1 reference

based on heuristic

inferred from page(s)

published in

Cell

1 reference

2 August 2017

161

1 reference

2 August 2017

3

1 reference

2 August 2017

459-469

1 reference

describes a project that uses

2 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4505837/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Mitochondrial DNA disease-molecular insights and potential routes to a cure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

The maintenance of mitochondrial DNA integrity--critical analysis and update

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Towards germline gene therapy of inherited mitochondrial diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

A transcription activator-like effector toolbox for genome engineering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Manipulation of mtDNA heteroplasmy in all striated muscles of newborn mice by AAV9-mediated delivery of a mitochondria-targeted restriction endonuclease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Targeting DNA double-strand breaks with TAL effector nucleases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Organ-specific shifts in mtDNA heteroplasmy following systemic delivery of a mitochondria-targeted restriction endonuclease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

The role of mitochondrial DNA copy number in mammalian fertility.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

The inheritance of pathogenic mitochondrial DNA mutations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Development of a single-chain, quasi-dimeric zinc-finger nuclease for the selective degradation of mutated human mitochondrial DNA.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Selective elimination of mutant mitochondrial genomes as therapeutic strategy for the treatment of NARP and MILS syndromes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Mitochondrial disease: a practical approach for primary care physicians.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Mitochondrial DNA and the mammalian oocyte.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Sequence-specific modification of mitochondrial DNA using a chimeric zinc finger methylase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Transmission of mitochondrial DNA disorders: possibilities for the future.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Mitochondrial DNA mutations in human disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Ancient Invasions: From Endosymbionts to Organelles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Genome-wide analysis of mRNAs targeted to yeast mitochondria

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

A mitochondrial DNA mutation at nucleotide pair 14459 of the NADH dehydrogenase subunit 6 gene associated with maternally inherited Leber hereditary optic neuropathy and dystonia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Sequence and organization of the human mitochondrial genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Polar body genome transfer for preventing the transmission of inherited mitochondrial diseases.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Assisted reproduction. FDA considers trials of 'three-parent embryos'.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Regulators weigh benefits of 'three-parent' fertilization.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Medicine. Mitochondrial replacement, evolution, and the clinic.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4505837

The inheritance of mitochondrial DNA heteroplasmy: random drift, selection or both?

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25910206

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2015.03.051

1 reference

2 August 2017

1 reference

2 August 2017

1 reference