(Q34479725)

2 August 2017

title

Heat shock proteins and Drosophila aging (English)

1 reference

2 August 2017

0 references

John Tower

1

1 reference

2 August 2017

publication date

16 September 2010

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2 August 2017

published in

Experimental Gerontology

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2 August 2017

volume

46

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2 August 2017

issue

5

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2 August 2017

page(s)

355-362

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ATP binding to Hsp90 is sufficient for effective chaperoning of p53 protein

2 August 2017

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Reduced expression of alpha-1,2-mannosidase I extends lifespan in Drosophila melanogaster and Caenorhabditis elegans

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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The Hsp27 gene is not required for Drosophila development but its activity is associated with starvation resistance

6 July 2018

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Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes

6 July 2018

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Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila.

6 July 2018

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Remarkable longevity and stress resistance of nematode PI3K-null mutants

6 July 2018

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Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila

6 July 2018

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Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis

6 July 2018

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Structure, properties, and functions of the human small heat-shock protein HSP22 (HspB8, H11, E2IG1): a critical review.

6 July 2018

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Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice

6 July 2018

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Aging and regulated protein degradation: who has the UPPer hand?

6 July 2018

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Heat shock responses for understanding diseases of protein denaturation

6 July 2018

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Aging perturbs 26S proteasome assembly in Drosophila melanogaster

6 July 2018

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Structure, function, property, and role in neurologic diseases and other diseases of the sHsp22.

6 July 2018

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Chaperone regulation of the heat shock protein response

6 July 2018

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6 July 2018

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Longevity and the stress response in Drosophila

6 July 2018

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Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties

6 July 2018

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6 July 2018

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Serum heat shock protein 70 level as a biomarker of exceptional longevity

6 July 2018

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Sex-specific regulation of aging and apoptosis

6 July 2018

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Differences in the chaperone-like activities of the four main small heat shock proteins of Drosophila melanogaster

6 July 2018

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Protein synthesis upon acute nutrient restriction relies on proteasome function

6 July 2018

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Age-specific and lifetime behavior patterns in Drosophila melanogaster and the Mediterranean fruit fly, Ceratitis capitata

6 July 2018

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Menin is a regulator of the stress response in Drosophila melanogaster

6 July 2018

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Loss of Hsp70 in Drosophila is pleiotropic, with effects on thermotolerance, recovery from heat shock and neurodegeneration

6 July 2018

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A Drosophila model of mitochondrial DNA replication: proteins, genes and regulation.

6 July 2018

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A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans

6 July 2018

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Functional senescence in Drosophila melanogaster

6 July 2018

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JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling

6 July 2018

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JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.

6 July 2018

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On mechanisms that control heat shock transcription factor activity in metazoan cells

6 July 2018

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Evolutionary and mechanistic theories of aging.

6 July 2018

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Multiple-stress analysis for isolation of Drosophila longevity genes

6 July 2018

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Sex-specific effects of interventions that extend fly life span.

6 July 2018

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Mitochondrial "swirls" induced by oxygen stress and in the Drosophila mutant hyperswirl

6 July 2018

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Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

6 July 2018

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6 July 2018

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Heat shock proteins and aging in Drosophila melanogaster

6 July 2018

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Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones

6 July 2018

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Expression of the Hsp23 chaperone during Drosophila embryogenesis: association to distinct neural and glial lineages

6 July 2018

1 reference

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JNK Signaling Confers Tolerance to Oxidative Stress and Extends Lifespan in Drosophila

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Proteasomes and molecular chaperones: cellular machinery responsible for folding and destruction of unfolded proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Cancer and ageing: rival demons?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

On the role of Hsp27 in regulating apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Actin cytoskeleton and small heat shock proteins: how do they interact?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Dynamic remodeling of transcription complexes by molecular chaperones

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Stress response genes protect against lethal effects of sleep deprivation in Drosophila

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Drosophila small heat shock proteins: cell and organelle-specific chaperones?

6 July 2018

1 reference

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Molecular chaperones in the cytosol: from nascent chain to folded protein

6 July 2018

1 reference

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Stress resistance as a determinate of C. elegans lifespan

6 July 2018

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Neural-specific overexpression of drosophila plenty of SH3s (DPOSH) extends the longevity of adult flies

6 July 2018

1 reference

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Life extension in Drosophila by feeding a drug.

6 July 2018

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Genome-wide study of aging and oxidative stress response in Drosophila melanogaster

6 July 2018

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Increased hsp22 RNA levels in Drosophila lines genetically selected for increased longevity

6 July 2018

1 reference

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The small heat shock protein Hsp22 of Drosophila melanogaster is a mitochondrial protein displaying oligomeric organization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Sequence requirements for upregulated expression of Drosophila hsp70 transgenes during aging

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Aging-specific expression of Drosophila hsp22.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Hsp90 as a capacitor for morphological evolution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Genealogy of the alpha-crystallin--small heat-shock protein superfamily

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Chaperoning extended life.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Protein import into mitochondria

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Discovery of the heat shock response

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Regulation of heat shock gene induction and expression during Drosophila development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1- and staurosporine-induced cell death.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Constitutive expression of human hsp27, Drosophila hsp27, or human alpha B-crystallin confers resistance to TNF- and oxidative stress-induced cytotoxicity in stably transfected murine L929 fibroblasts.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Response of heat shock element within the human HSP70 promoter to mutated p53 genes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Muscle-specific expression of Drosophila hsp70 in response to aging and oxidative stress

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Age dependent changes in mitochondria.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Iron accumulation during development and ageing of Drosophila

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Aging results in an unusual expression of Drosophila heat shock proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Interaction of Drosophila 27,000 Mr heat-shock protein with the nucleus of heat-shocked and ecdysone-stimulated culture cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

The consequences of expressing hsp70 in Drosophila cells at normal temperatures

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Expression of Drosophila's 27 kDa heat shock protein into rodent cells confers thermal resistance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Predicting death in female Drosophila

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

The effect of neuronal expression of heat shock proteins 26 and 27 on lifespan, neurodegeneration, and apoptosis in Drosophila.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Life span alteration after irradiation in Drosophila melanogaster strains with mutations of Hsf and Hsps.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Chaperone-dependent stabilization and degradation of p53 mutants

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Acquired temperature-sensitive paralysis as a biomarker of declining neuronal function in aging Drosophila.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Sex specific effects of heat induced hormesis in Hsf-deficient Drosophila melanogaster

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Dynamics of the action of dFOXO on adult mortality in Drosophila

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

A conditional pan-neuronal Drosophila model of spinocerebellar ataxia 7 with a reversible adult phenotype suitable for identifying modifier genes.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Heat-induced hormesis in longevity of two sibling Drosophila species

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

POSH, a scaffold protein for JNK signaling, binds to ALG-2 and ALIX in Drosophila

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Visualizing hidden heterogeneity in isogenic populations of C. elegans

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Lifespan extension and elevated hsp gene expression in Drosophila caused by histone deacetylase inhibitors

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Mechanisms of Suppression of {alpha}-Synuclein Neurotoxicity by Geldanamycin in Drosophila.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Doxycycline-regulated over-expression of hsp22 has negative effects on stress resistance and life span in adult Drosophila melanogaster

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

A new method for manipulating transgenes: engineering heat tolerance in a complex, multicellular organism.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Decreased lifespan in the absence of expression of the mitochondrial small heat shock protein Hsp22 in Drosophila

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Long-lived Drosophila with overexpressed dFOXO in adult fat body

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Lifespan extension of Drosophila melanogaster through hormesis by repeated mild heat stress.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Application of the gene search system to screen for longevity genes in Drosophila.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Effects of mild heat shocks at young age on aging and longevity in Drosophila melanogaster.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Oxidative stress and aging reduce COX I RNA and cytochrome oxidase activity in Drosophila.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Stage-specific localization of the small heat shock protein Hsp27 during oogenesis in Drosophila melanogaster

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Mitochondrial DNA remains intact during Drosophila aging, but the levels of mitochondrial transcripts are significantly reduced.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Sequence of the new Drosophila melanogaster small heat-shock-related gene, lethal(2) essential for life [l(2)efl], at locus 59F4,5.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018744

Locomotor activity as a function of age and life span in Drosophila melanogaster overexpressing hsp70

27 October 2018

1 reference

12 December 2020

Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin-like signals

1 reference

12 December 2020

Detection of Inactive Enzyme Molecules in Ageing Organisms

1 reference

12 December 2020

SnapShot: molecular chaperones, Part II

1 reference

12 December 2020

SnapShot: molecular chaperones, Part I

1 reference

12 December 2020

Regulation of the human hsp70 promoter by p53

1 reference

12 December 2020

Protein oxidation and aging

1 reference

12 December 2020

Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions

1 reference

12 December 2020

Mitochondrial changes in flight muscles of normal and flightless Drosophila melanogaster with age

1 reference

12 December 2020

10.1016/J.EXGER.2010.09.002

Identifiers

DOI

1 reference

2 August 2017

1 reference

2 August 2017

1 reference