(Q84551753)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19749793%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19749793%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19749793%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Maciej Olszewski

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19749793%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

M Gutkowska

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19749793%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

A Helwak

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19749793%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

M Zylicz

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19749793%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

A Zylicz

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19749793%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

publication date

14 September 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19749793%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19749793%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19749793%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

issue

48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19749793%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

page(s)

4284-4294

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19749793%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2009.281

7 February 2020

exact match

0 references

cites work

Roles of molecular chaperones in cytoplasmic protein folding

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Chaperoning checkpoint kinase 1 (Chk1), an Hsp90 client, with purified chaperones

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

p53 contains large unstructured regions in its native state

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Folding and misfolding mechanisms of the p53 DNA binding domain at physiological temperature

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Solution structure of p53 core domain: structural basis for its instability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Inactive full-length p53 mutants lacking dominant wild-type p53 inhibition highlight loss of heterozygosity as an important aspect of p53 status in human cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

HSP70 binding sites in the tumor suppressor protein p53.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refolding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: implications for "mutant conformation".

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Allosteric regulation of the thermostability and DNA binding activity of human p53 by specific interacting proteins. CRC Cell Transformation Group

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

The assembly and intermolecular properties of the hsp70-Hop-hsp90 molecular chaperone complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Requirement of heat shock protein 90 for human hepatitis B virus reverse transcriptase function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

A single amino acid substitution differentiates Hsp70-dependent effects on alpha-synuclein degradation and toxicity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Transcriptional regulation by p53: one protein, many possibilities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Depletion of GAK/auxilin 2 inhibits receptor-mediated endocytosis and recruitment of both clathrin and clathrin adaptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Escherichia coli DnaJ and GrpE heat shock proteins jointly stimulate ATPase activity of DnaK

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Temperature-dependent switching between "wild-type" and "mutant" forms of p53-Val135.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Stepwise assembly of a glucocorticoid receptor.hsp90 heterocomplex resolves two sequential ATP-dependent events involving first hsp70 and then hsp90 in opening of the steroid binding pocket

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Hsp90 is essential for restoring cellular functions of temperature-sensitive p53 mutant protein but not for stabilization and activation of wild-type p53: implications for cancer therapy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Chaperone-dependent stabilization and degradation of p53 mutants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Dominant-interfering Hsc70 mutants disrupt multiple stages of the clathrin-coated vesicle cycle in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Specific interaction between the p53 cellular tumour antigen and major heat shock proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

CRINEPT-TROSY NMR reveals p53 core domain bound in an unfolded form to the chaperone Hsp90.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Hsp90 as a capacitor for morphological evolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Under cover: causes, effects and implications of Hsp90-mediated genetic capacitance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

MDM2 binding induces a conformational change in p53 that is opposed by heat-shock protein 90 and precedes p53 proteasomal degradation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Reactivation of mutant p53: molecular mechanisms and therapeutic potential

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Heat shock protein 84 forms a complex with mutant p53 protein predominantly within a cytoplasmic compartment of the cell

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Hsp90 isoforms: functions, expression and clinical importance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Interaction between hsp70 and hsp40, eukaryotic homologues of DnaK and DnaJ, in human cells expressing mutant-type p53.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

p53 in health and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Hsp90 chaperones wild-type p53 tumor suppressor protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Phosphorylation and hsp90 binding mediate heat shock stabilization of p53

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Hsp70 and Hsp90--a relay team for protein folding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281

Hsp70 interactions with the p53 tumour suppressor protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.281