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p38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines.
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Europe PubMed Central
PubMed publication ID
11774793
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
review article
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Europe PubMed Central
title
p38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11774793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
main subject
inflammation
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author name string
J L Adams
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1
1 reference
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Europe PubMed Central
PubMed publication ID
11774793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
A M Badger
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2
1 reference
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Europe PubMed Central
PubMed publication ID
11774793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json
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5 December 2019
S Kumar
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3
1 reference
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Europe PubMed Central
PubMed publication ID
11774793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json
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5 December 2019
J C Lee
series ordinal
4
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Europe PubMed Central
PubMed publication ID
11774793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
publication date
1 January 2001
1 reference
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Europe PubMed Central
PubMed publication ID
11774793
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
published in
Progress in medicinal chemistry
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11774793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
volume
38
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11774793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
page(s)
1-60
1 reference
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Europe PubMed Central
PubMed publication ID
11774793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
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7 January 2021
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Inhibition of monocyte IL-1 production by the anti-inflammatory compound, SK&F 86002
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7 January 2021
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Effect of SK&F 86002 on cytokine production by human monocytes
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7 January 2021
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Pyridinyl imidazoles inhibit IL-1 and TNF production at the protein level
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7 January 2021
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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
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7 January 2021
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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
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https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
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7 January 2021
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MAP kinase pathways
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
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7 January 2021
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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
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Crossref
reference URL
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7 January 2021
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A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
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7 January 2021
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Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
1 reference
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Crossref
reference URL
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7 January 2021
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Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.
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7 January 2021
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Interleukin 1 alpha activates two forms of p54 alpha mitogen-activated protein kinase in rabbit liver
1 reference
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7 January 2021
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The stress-activated protein kinase subfamily of c-Jun kinases
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7 January 2021
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Localization of the human stress responsive MAP kinase-like CSAIDs binding protein (CSBP) gene to chromosome 6q21.3/21.2.
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7 January 2021
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Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein
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7 January 2021
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Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)
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7 January 2021
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Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles
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7 January 2021
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p38-2, a novel mitogen-activated protein kinase with distinct properties.
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
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7 January 2021
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inferred from DOI database lookup
Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6
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Crossref
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https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
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7 January 2021
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The primary structure of p38 gamma: a new member of p38 group of MAP kinases
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38)
1 reference
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reference URL
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7 January 2021
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inferred from DOI database lookup
Activation of the novel MAP kinase homologue SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Murine p38-delta mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the MAP kinase homologue RK requires the phosphorylation of Thr-180 and Tyr-182 and both residues are phosphorylated in chemically stressed KB cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
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7 January 2021
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Identification of MAP kinase domains by redirecting stress signals into growth factor responses
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structure-function studies of p38 mitogen-activated protein kinase. Loop 12 influences substrate specificity and autophosphorylation, but not upstream kinase selection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular determinants that mediate selective activation of p38 MAP kinase isoforms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MEK kinase 3 directly activates MKK6 and MKK7, specific activators of the p38 and c-Jun NH2-terminal kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein modification: docking sites for kinases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of two distinct regions of p38 MAPK required for substrate binding and phosphorylation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
3pK, a new mitogen-activated protein kinase-activated protein kinase located in the small cell lung cancer tumor suppressor gene region
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MAPKAPK5, a novel mitogen-activated protein kinase (MAPK)-activated protein kinase, is a substrate of the extracellular-regulated kinase (ERK) and p38 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of actin dynamics during stress and physiological stimulation by a signaling pathway involving p38 MAP kinase and heat-shock protein 27.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MAPKAP kinase 2 phosphorylates serum response factor in vitro and in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PRAK, a novel protein kinase regulated by the p38 MAP kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 Mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the MEF2 family of transcription factors by p38
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Convergence of MAP kinase pathways on the ternary complex factor Sap-1a
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic mechanism for p38 MAP kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic mechanism of the p38-alpha MAP kinase: phosphoryl transfer to synthetic peptides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytosolic Phospholipase A2 Is Phosphorylated in Collagen- and Thrombin-stimulated Human Platelets Independent of Protein Kinase C and Mitogen-activated Protein Kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The activation state of p38 mitogen-activated protein kinase determines the efficiency of ATP competition for pyridinylimidazole inhibitor binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
5,6-Diaryl-2,3-dihydroimidazo[2,1-b]thiazoles: a new class of immunoregulatory antiinflammatory agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antiinflammatory activity of 5,6-diaryl-2,3-dihydroimidazo[2,1-b]thiazoles. Isomeric 4-pyridyl and 4-substituted phenyl derivatives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SK&F 86002: a structurally novel anti-inflammatory agent that inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ovarian effects of SK&F 86002-A2 in the rat: site of action.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative biochemical and morphometric changes associated with induction of the hepatic mixed function oxidase system in the rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacology of the pyrroloimidazole, SK&F 105809--I. Inhibition of inflammatory cytokine production and of 5-lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pyrimidinylimidazole inhibitors of CSBP/p38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pyrroles and other heterocycles as inhibitors of p38 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of suppressive effects of a new anti-inflammatory compound, FR167653, on production of PGE2 and inflammatory cytokines, human monocytes, and alveolar macrophages in response to endotoxin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of FR167653, a cytokine suppressive agent, on endotoxin-induced disseminated intravascular coagulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Paradoxical activation of Raf by a novel Raf inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 mitogen-activated protein kinase inhibitors--mechanisms and therapeutic potentials
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structure of mitogen-activated protein kinase p38 at 2.1-A resolution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of p38 mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis of inhibitor selectivity in MAP kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonopsonic binding of type III Group B Streptococci to human neutrophils induces interleukin-8 release mediated by the p38 mitogen-activated protein kinase pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PAF-induced RANTES production by human airway smooth muscle cells requires both p38 MAP kinase and Erk
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RAC1/P38 MAPK signaling pathway controls beta1 integrin-induced interleukin-8 production in human natural killer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin 1 (IL1) and tumour necrosis factor (TNF) signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for p38 mitogen-activated protein kinase in platelet aggregation caused by collagen or a thromboxane analogue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective activation of JNK/SAPK by interleukin-1 in rabbit liver is mediated by MKK7
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of tumor necrosis factor mRNA translation by a rationally designed immunomodulatory peptide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of transcription by MAP kinase cascades
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas induces cytoplasmic apoptotic responses and activation of the MKK7-JNK/SAPK and MKK6-p38 pathways independent of CPP32-like proteases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis signaling pathway in T cells is composed of ICE/Ced-3 family proteases and MAP kinase kinase 6b
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Rb and E2F by signal transduction cascades: divergent effects of JNK1 and p38 kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor-alpha mediates antiapoptotic signals partially via p38 MAP kinase activation in human eosinophils
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of p38 mitogen-activated protein kinase by insulin in cultured fetal neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of p38 mitogen-activated protein kinase promote neuronal survival in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid and long-lasting suppression of the ATF-2 transcription factor is a common response to neuronal injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis of cerebellar granule cells induced by serum withdrawal, glutamate or beta-amyloid, is independent of Jun kinase or p38 mitogen activated protein kinase activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An inhibitor of p38 and JNK MAP kinases prevents activation of caspase and apoptosis of cultured cerebellar granule neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 kinase is activated in the Alzheimer's disease brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCaT cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis signal regulating kinase 1 (ASK1) after spinal cord injury in rats: possible involvement of ASK1-JNK and -p38 pathways in neuronal apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SB203580 reverses adrenomedullin's effect on proliferation and apoptosis in cultured mesangial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the p38 mitogen-activated protein kinase pathway by estrogen or by 4-hydroxytamoxifen is coupled to estrogen receptor-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 MAP kinase regulates TNF alpha-, IL-1 alpha- and PAF-induced RANTES and GM-CSF production by human bronchial epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 mitogen-activated protein kinase inhibition attenuates intercellular adhesion molecule-1 up-regulation on human pulmonary microvascular endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Models and mechanisms of exercise-induced asthma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hyperosmolarity-induced interleukin-8 expression in human bronchial epithelial cells through p38 mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidants and antioxidants as therapeutic targets in chronic obstructive pulmonary disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxic Stimulation of the Stress-activated Protein Kinases in Pulmonary Artery Fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MAP kinases, phosphatidylinositol 3-kinase, and p70 S6 kinase mediate the mitogenic response of human endothelial cells to vascular endothelial growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 mitogen-activated protein kinase activation is required for fibroblast growth factor-2-stimulated cell proliferation but not differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the signal transduction of basic fibroblast growth factor in endothelial cells during angiogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Role for p38MAPK/HSP27 Pathway in Smooth Muscle Cell Migration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the HIV-1 long terminal repeat by cytokines and environmental stress requires an active CSBP/p38 MAP kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of NF-kappa B and p38 MAP kinase is not sufficient for triggering efficient HIV gene expression in response to stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The critical role of p38 MAP kinase in T cell HIV-1 replication.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of p38 mitogen-activated protein kinase in HIV type 1 production in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 mitogen-activated protein kinase and c-jun-NH2-terminal kinase regulate RANTES production by influenza virus-infected human bronchial epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of p38 mitogen-activated protein kinase in rhinovirus-induced cytokine production by bronchial epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the mitogen-activated protein kinase p38 by human cytomegalovirus infection through two distinct pathways: a novel mechanism for activation of p38.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epstein-Barr virus immediate-early proteins BZLF1 and BRLF1 activate the ATF2 transcription factor by increasing the levels of phosphorylated p38 and c-Jun N-terminal kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of p38 mitogen-activated protein kinase and c-Jun NH(2)-terminal kinase by double-stranded RNA and encephalomyocarditis virus: involvement of RNase L, protein kinase R, and alternative pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Herpes simplex virus type 1 infection stimulates p38/c-Jun N-terminal mitogen-activated protein kinase pathways and activates transcription factor AP-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acute infection of Sindbis virus induces phosphorylation and intracellular translocation of small heat shock protein HSP27 and activation of p38 MAP kinase signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of ERK2 by respiratory syncytial virus in A549 cells is linked to the production of interleukin 8.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokine suppressive anti-inflammatory compounds inhibit bone resorption in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective activation of the mitogen-activated protein kinase subgroups c-Jun NH2 terminal kinase and p38 by IL-1 and TNF in human articular chondrocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immortalized human adult articular chondrocytes maintain cartilage-specific phenotype and responses to interleukin-1beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of nitric oxide and prostaglandin E2 production by CSAIDS (SB203580) in murine macrophages and bovine chondrocytes stimulated with LPS.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of MAP kinase cascades in inducing arginine transporters and nitric oxide synthetase in RAW264 macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of p38 mitogen-activated protein kinase in IL-6 and IL-8 production from the TNF-alpha- or IL-1beta-stimulated rheumatoid synovial fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of collagenase-3 (MMP-13) expression in human skin fibroblasts by three-dimensional collagen is mediated by p38 mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacologic characterization of the antiinflammatory properties of a new dual inhibitor of lipoxygenase and cyclooxygenase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
6-Amino-2-(4-fluorophenyl)-4-methoxy-3- (4-pyridyl)-1H-pyrrolo[2, 3-b]pyridine (RWJ 68354): a potent and selective p38 kinase inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of inhibitors of eicosanoid metabolism in murine collagen-induced arthritis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inflammatory mediators and stroke: new opportunities for novel therapeutics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of p38 MAP kinase in myocardial stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A p38 MAP kinase inhibitor SB203580 inhibits CD28-dependent T cell proliferation and IL-2 production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pyridinyl imidazoles inhibit the inflammatory phase of delayed type hypersensitivity reactions without affecting T-dependent immune responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pyridinyl imidazole inhibitor SB203580 blocks phosphoinositide-dependent protein kinase activity, protein kinase B phosphorylation, and retinoblastoma hyperphosphorylation in interleukin-2-stimulated T cells independently of p38 mitogen-activate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Raf-1 is activated by the p38 mitogen-activated protein kinase inhibitor, SB203580.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potent inhibitors of the MAP kinase p38
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A synthetic inhibitor of the mitogen-activated protein kinase cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of MAP kinase kinase (MEK) results in an anti-inflammatory response in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bicyclic imidazoles as a novel class of cytokine biosynthesis inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor-beta induces collagenase-3 expression by human gingival fibroblasts via p38 mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970091-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0079-6468(08)70091-2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11774793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
PubMed publication ID
11774793
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11774793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11774793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
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