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Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6.
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stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
title
Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
main subject
phosphorylation
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inferred from title
author
Jan Mašek
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
Pavel Krejčí
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
Gunnar Schulte
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7
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Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
J. Silvio Gutkind
series ordinal
8
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PMCID
3019858
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
Vítězslav Bryja
series ordinal
9
1 reference
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Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
Alois Kozubík
series ordinal
6
object named as
Alois Kozubík
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
author name string
Igor Červenka
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
Joshua Wolf
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
William R Wilcox
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
language of work or name
English
0 references
publication date
25 October 2010
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Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
published in
Molecular and Cellular Biology
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
volume
31
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
page(s)
179-189
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
cites work
Cell cycle control of wnt receptor activation
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EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin.
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6 July 2018
G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019858
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Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6.
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6 July 2018
Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling
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reference URL
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p38 mitogen-activated protein kinase regulates canonical Wnt-beta-catenin signaling by inactivation of GSK3beta
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Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development
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6 July 2018
LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin
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Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation.
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Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6.
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PubMed Central
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G alpha o mediates WNT-JNK signaling through dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells
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Multiple PPPS/TP motifs act in a combinatorial fashion to transduce Wnt signaling through LRP6.
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Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.
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6 July 2018
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
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PubMed Central
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6 July 2018
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6 July 2018
Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin
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Balancing cell adhesion and Wnt signaling, the key role of beta-catenin
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6 July 2018
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
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6 July 2018
Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction
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6 July 2018
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions
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FGF2 inhibits proliferation and alters the cartilage-like phenotype of RCS cells
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6 July 2018
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FGF-1 and FGF-2 modulate the E-cadherin/catenin system in pancreatic adenocarcinoma cell lines
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LDL-receptor-related proteins in Wnt signal transduction
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6 July 2018
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6 July 2018
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
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6 July 2018
A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function
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6 July 2018
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Casein kinase I transduces Wnt signals
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27 October 2018
Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20974802
retrieved
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based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.00550-10
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
PMCID
3019858
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
PubMed ID
20974802
1 reference
stated in
Europe PubMed Central
PMCID
3019858
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20974802%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
ResearchGate publication ID
47544241
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